Introduction: Lightning strike is a rare, deadly natural phenomenon, affecting multiple organ systems with serious complications. Known complications include but are not limited to myocardial infarction, arrhythmias, cardiac contusion, stroke, cutaneous burns, pulmonary disorders, neurological disorders, acute renal failure, and death. Electrophysiological effects of a strike on the heart may result in ventricular fibrillation, asystole, QT prolongation, supraventricular tachycardia, and nonspecific ST-T changes.Case report: Here we report the case of a patient whose medical history revealed syncope due to being struck by lightning, and electrocardiography changes were identified together with positive troponin I value during follow-up.Conclusion: Patients who manifest cardiac and neurological symptoms and signs should be monitored and followed-up for at least 24-48 h with cardiac investigation, neuromuscular evaluation, and supportive treatment (especially rhabdomyolysis).