The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection

KILIÇ, Raşit; ERGÜL, BİLAL; Kurt, Ali

The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection

Raşit KILIÇ, (Ahi Evran Üniversitesi Tıp Fakültesi Göz Hastalıkları Ana Bilim Dalı, Kırşehir)

Ali KURT, (Ahi Evran Üniversitesi Tıp Fakültesi Göz Hastalıkları Ana Bilim Dalı, Kırşehir)

Bilal ERGÜL (Ahi Evran Üniversitesi, Eğitim ve Araştırma Hastanesi, Gastroenteroloji Kliniği, Kırşehir, Türkiye)

Retina-Vitreus

1 0

Yıl: 2018 Cilt: 27 Sayı: 1 Sayfa Aralığı: 38 - 42 Metin Dili: İngilizce İndeks Tarihi: 07-05-2019

The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection

Öz:

Aim: Our aim was to compare the choroidal thickness in patients with chronic hepatitis B virus (HBV) infection and age- and gen-der-matched healthy volunteers.Materials and Methods: A total of 69 chronic HBV infection cases and 64 age- and gender-matched controls were evaluated. The chronicHBV infection cases were divided into two subgroups as inactive carriers (38 cases) and those being treated (31 cases). The right eye wasevaluated in all subjects. The sections were measured horizontally across the fovea at 500-μm intervals using enhanced depth imagingoptical coherence tomography. The measurements were made at a total of 7 measurement points up to 1500 μm nasal and temporal to thefovea.Results: There was no signifi cant difference between the patient and control groups in terms of age, gender, body mass index, intraocularpressure and spherical equivalent (p>0.05). Choroidal thicknesses in chronic HBV patients were thicker than in the controls but thisdifference was not statistically signifi cant (p>0.05). There was no signifi cant correlation between disease duration and choroidal thickness.There was also no signifi cant difference between the subgroups for choroidal thickness (p>0.05).Conclusions: We found that the choroidal thicknesses were higher in chronic HBV patients than in healthy control subjects at allmeasurement points but these differences were not statistically signifi cant. The effect of chronic HBV infection on choroidal vascularstructures is not at a signifi cant level that can be determined with EDI-OCT.

Anahtar Kelime:

Konular: Göz Hastalıkları

Kronik Hepatit B Virus Enfeksiyonu Olan Hastalarda Koroidal Kalınlığın Değerlendirilmesi

Öz:

Amaç: Kronik hepatit B virus (HBV) enfeksiyonu olan hastalar ile yaş ve cinsiyet yönünden benzer sağlıklı gönüllüler arasında koroidal kalınlığı karşılaştırmaktır. Materyal ve Metod: Toplam 69 kronik HBV enfeksiyon olgusu ve 64 yaş ve cinsiyet benzer özellikte kontrol değerlendirildi. Kronik HBV enfeksiyon olguları inaktif taşıyıcılar (38 olgu) ve tedavi olanlar (31 olgu) olarak iki alt gruba ayrıldı. Tüm olgularda sağ göz değerlendirildi. Kesitler, geliştirilmiş derinlemesine görüntüleme optik koherens tomografi kullanılarak 500 μm aralıklarla fovea boyunca horizontal olarak ölçüldü. Foveada ve nazal ve temporalde horizontal olarak foveadan 500 μm aralıklarla 1500 mikrometreye kadar toplam 7 noktada ölçümler yapıldı. Bulgular: Hasta ve kontrol gruplar arasında yaş, cinsiyet, vücut kitle endeksi, göz içi basıncı ve sferik eşdeğer açısından anlamlı farklılık yoktu (p>0.05). Koroidal kalınlık kronik HBV hastalarında daha kalın bulundu, fakat bu farklılık istatistiksel olarak anlamlı değildi (p>0.05). Hastalık süresi ve koroidal kalınlık arasında anlamlı bir korelasyon yoktu. Alt gruplar arasında koroidal kalınlık açısından da anlamlı farklılık yoktu (p>0.05). Sonuç: Kronik HBV hastalarında koroidal kalınlığı tüm ölçüm noktalarında sağlıklı kontrollerden daha kalın bulduk, fakat bu farklılık istatistiksel olarak anlamlı değildi. Kronik HBV enfeksiyonunun koroidal damar yapıları üzerine etkisi EDI-OCT ile saptanabilen anlamlı bir düzeyde değildir.

Anahtar Kelime:

Konular: Göz Hastalıkları

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik

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APA	KILIÇ R, Kurt A, ERGÜL B (2018). The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. , 38 - 42.
Chicago	KILIÇ Raşit,Kurt Ali,ERGÜL BİLAL The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. (2018): 38 - 42.
MLA	KILIÇ Raşit,Kurt Ali,ERGÜL BİLAL The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. , 2018, ss.38 - 42.
AMA	KILIÇ R,Kurt A,ERGÜL B The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. . 2018; 38 - 42.
Vancouver	KILIÇ R,Kurt A,ERGÜL B The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. . 2018; 38 - 42.
IEEE	KILIÇ R,Kurt A,ERGÜL B "The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection." , ss.38 - 42, 2018.
ISNAD	KILIÇ, Raşit vd. "The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection". (2018), 38-42.

APA	KILIÇ R, Kurt A, ERGÜL B (2018). The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. Retina-Vitreus, 27(1), 38 - 42.
Chicago	KILIÇ Raşit,Kurt Ali,ERGÜL BİLAL The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. Retina-Vitreus 27, no.1 (2018): 38 - 42.
MLA	KILIÇ Raşit,Kurt Ali,ERGÜL BİLAL The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. Retina-Vitreus, vol.27, no.1, 2018, ss.38 - 42.
AMA	KILIÇ R,Kurt A,ERGÜL B The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. Retina-Vitreus. 2018; 27(1): 38 - 42.
Vancouver	KILIÇ R,Kurt A,ERGÜL B The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection. Retina-Vitreus. 2018; 27(1): 38 - 42.
IEEE	KILIÇ R,Kurt A,ERGÜL B "The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection." Retina-Vitreus, 27, ss.38 - 42, 2018.
ISNAD	KILIÇ, Raşit vd. "The Evaluation of Choroidal Thickness in Patients With Chronic Hepatitis B Virus Infection". Retina-Vitreus 27/1 (2018), 38-42.