Objective: The aim of the present study was to share our experiences of the use of self-expandable metallic stent forthe upper gastrointestinal tract disease.Material and Methods: We retrospectively reviewed the medical records of 18 patients who underwent self-expandablemetallic stent implantation procedure for anastomosis stricture, anastomosis leak, or spontaneous fistula ofthe upper gastrointestinal tract at two different surgery clinics. Self-expandable metallic stent implantation procedureswere performed while keeping the patient under sedation and the correct stent localization was verified usingfluoroscopy. The stent localization and possible stent migration were checked using X-ray films taken a few daysafter the stenting procedure.Results: Overall, 25 self-expandable metallic stents were implanted in 18 patients (malignant, 13; benign, 5) agedbetween 19 and 89 years. The indications for self-expandable metallic stent implantation were as follows: malignantgastric stricture (inoperable; n=6), malignant esophageal stricture (inoperable; n=4), staple line leak (laparoscopicsleeve gastrectomy; n=4), esophagojejunostomy anastomotic leak (total gastrectomy+Roux-en-Yesophagojejunostomy;n=2), and stricture (total gastrectomy+Roux-en-Yesophagojejunostomy; n=1), and esophagopleural fistula(pulmonary tuberculosis; n=1). A favorable outcome was achieved in a single session in 15 patients, whereas morethan two sessions of stenting were necessary in the remaining three patients. Among the patients who underwentesophagojejunal anastomosis (n=3), self-expandable metallic stents were successfully deployed in a single session intwo patients to relieve anastomosis leak (n=1) and anastomosis stricture (n=1); the remaining patients underwentfour self-expandable metallic stent implantation procedures to relieve anastomosis leak and subsequent recurrentstrictures. No complications developed during the stenting procedure. Three of the four patients who developedmortality had advanced stage esophageal cancer, whereas one patient had morbid obesity and developed stapleline leakage.Conclusion: Endoscopic self-expandable metallic stent implantation under fluoroscopic guidance is a low-morbidityand effective procedure for the management of advanced stage tumors of the gastrointestinal tract and the eliminationof postoperative complications.