The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients

AKGÜL, Gökhan Giray; GÜLÇELİK, Mehmet Ali; özdemir, yılmaz; Colakoglu, Muhammet Kadri

The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients

Muhammet Kadri ÇOLAKOĞLU, (Department of Surgical Oncology, Recep Tayyip Erdogan University School of Medicine, Rize, Turkey)

Yılmaz ÖZDEMİR, (Erzurum Eğitim ve Araştırma Hastanesi, Erzurum, Türkiye)

Gökhan Giray AKGÜL, (Department of Surgical Oncology, Mersin University School of Medicine, Mersin, Turkey)

Mehmet Ali GÜLÇELİK (Department of Surgery, University of Health Science, Gülhane Research and Training Hospital, Ankara, Turkey)

ACTA ONCOLOGICA TURCICA

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Yıl: 2018 Cilt: 51 Sayı: 2 Sayfa Aralığı: 205 - 212 Metin Dili: İngilizce İndeks Tarihi: 26-03-2019

The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients

Öz:

INTRODUCTION: The aim of this study to compare the success rates of radionuclide and methylene blue methods in detecting sentinel lymph nodes and evaluate the success rates of techniques or technique combinations in breast cancer patients. METHODS: In this prospective study we evaluated 287 breast cancer patients referred to Ankara Oncology Training and Research Hospital between February 2006 and March 2010. Patients whom we performed methylene blue method alone was named as Group I, radiocolloid substance method alone as Group II and both methylene blue and radiocolloid method as Group III. Patients dispatched groups randomly. We calculated the overall success rate and success rates of each techniques seperately. RESULTS: When considered for all groups overall sentinel lymph node detecting success rate was 83,3%. When considered for each group, success rate was 80% for group I (methylene blue alone group), 84,9% for group II (radiocolloid substance alone group) and 90,6% for group III (combined group). Statistically there was no difference between group I and group II (p=0,425) but there was a statistical difference between group I and group III (p<0,05). DISCUSSION and CONCLUSION: The usage of vital dyes and radioactive colloidal substances alone has high success rates but combined method increases the success rate obviously.

Anahtar Kelime:

Konular: Onkoloji

Meme Kanserli Hastalarda Aksiller Evreleme Amaçlı İntraoperatif Sentinel Lenf Nosu Saptanmasında Radyokolloid Metilen Mavisi ve Kombine Yöntemlerin Karşılaştırılması

Öz:

GİRİŞ ve AMAÇ: Çalışmanın amacı sentinel lenf nodu saptanmasında radyonüklid ve metilen mevisi metotlarının başarı oranlarını karşılaştırmak ve meme kanseri bulunan hastalarda bu teknik veya teknik kombinasyonlarının başarı oranlarını değerlendirmektir. YÖNTEM ve GEREÇLER: Bu prospektif çalışmada Şubat 2006 ve Mart 2010 tarihleri arasında Ankara Onkoloji Eğitim ve Araştırma Hastanesine başvuran 287 meme kanseri hastası değerlendirilmiştir. Sadece metilen mavisi metodu uygulanan hastalara Grup I, sadece radyokolloid madde metodu uygulanan hastalara Grup II, hem metilen mavisi hem de radyokolloid madde uygulanan hastalara ise Grup II adı verildi. Hastalar gruplara rastgele olarak dağıtıldı. Her bir tekniğin başarı oranları ve toplam başarı oranları karşılaştırıldı. BULGULAR: Tüm gruplar ele alındığında sentinel lenf nodu saptanmasında toplam başarı oranı %83,3 olarak hesaplandı Gruplara ayrı ayrı bakıldığında Grup I (tek başına metilen mavisi) için başarı oranı %80, Grup II (tek başına radyokolloid madde) için %84,9 ve Grup III (kombine grup) için %90.6 başarı oranı hesaplandı. İstatistiksel olarak Grup I ve Grup II arasında fark görülmezken (p=0,425) Grup I ve Grup III arasında istatistiksel olarak anlamlı fark izlendi (p<0,05). TARTIŞMA ve SONUÇ: Vital boyaların ve radyoaktif koloidal maddelerin tek başına kullanımında sentinel lenf nodu saptanması başarı oranları yüksektir ancak metotlar kombine edildiğinde bu başarı oranı anlamlı şekilde artmaktadır.

Anahtar Kelime:

Konular: Onkoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Colakoglu M, özdemir y, AKGÜL G, GÜLÇELİK M (2018). The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. , 205 - 212.
Chicago	Colakoglu Muhammet Kadri,özdemir yılmaz,AKGÜL Gökhan Giray,GÜLÇELİK Mehmet Ali The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. (2018): 205 - 212.
MLA	Colakoglu Muhammet Kadri,özdemir yılmaz,AKGÜL Gökhan Giray,GÜLÇELİK Mehmet Ali The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. , 2018, ss.205 - 212.
AMA	Colakoglu M,özdemir y,AKGÜL G,GÜLÇELİK M The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. . 2018; 205 - 212.
Vancouver	Colakoglu M,özdemir y,AKGÜL G,GÜLÇELİK M The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. . 2018; 205 - 212.
IEEE	Colakoglu M,özdemir y,AKGÜL G,GÜLÇELİK M "The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients." , ss.205 - 212, 2018.
ISNAD	Colakoglu, Muhammet Kadri vd. "The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients". (2018), 205-212.

APA	Colakoglu M, özdemir y, AKGÜL G, GÜLÇELİK M (2018). The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. ACTA ONCOLOGICA TURCICA, 51(2), 205 - 212.
Chicago	Colakoglu Muhammet Kadri,özdemir yılmaz,AKGÜL Gökhan Giray,GÜLÇELİK Mehmet Ali The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. ACTA ONCOLOGICA TURCICA 51, no.2 (2018): 205 - 212.
MLA	Colakoglu Muhammet Kadri,özdemir yılmaz,AKGÜL Gökhan Giray,GÜLÇELİK Mehmet Ali The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. ACTA ONCOLOGICA TURCICA, vol.51, no.2, 2018, ss.205 - 212.
AMA	Colakoglu M,özdemir y,AKGÜL G,GÜLÇELİK M The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. ACTA ONCOLOGICA TURCICA. 2018; 51(2): 205 - 212.
Vancouver	Colakoglu M,özdemir y,AKGÜL G,GÜLÇELİK M The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients. ACTA ONCOLOGICA TURCICA. 2018; 51(2): 205 - 212.
IEEE	Colakoglu M,özdemir y,AKGÜL G,GÜLÇELİK M "The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients." ACTA ONCOLOGICA TURCICA, 51, ss.205 - 212, 2018.
ISNAD	Colakoglu, Muhammet Kadri vd. "The Comparison of Radiocolloid, Methylene Blue and Combined Methods for Detecting Sentinel Lymph Node for Axillary Staging in Breast Cancer Patients". ACTA ONCOLOGICA TURCICA 51/2 (2018), 205-212.