Donors are generally volunteers without any sanitary problems. For this reason, security of the anesthesia practice and ICU admission period is significant. The goal of present study was to determine whether there was any important coalition among different positive end-expiratory pressure (PEEP) level hemodynamics and ICU admission in donor patients. This study was performed with40 patients who underwent general anesthesia. Patients were divided into two groups by their PEEP as0 cm H20 in the first group (group Z), and 10 H20 in the second group (group H). We investigated the data concerning demographical data, perioperative values, hemodynamic parameters, intraoperative blood loss, andICU admission. Patient characteristic,characteristicsand perioperative values were similar among the groups. Mean arterial pressure, and central venous pressure were importantly different among the groups (P<.05). Intraoperative bleeding remained statistically unchanged in both groups. The median ICU admission after surgery was longer in group Z versus the group H (2 and 1 days per patient, respectively; P>.05). We have concluded that our data pool is low and single-centered,we determined that PEEP values (10 cm H2O) may be a decisive element for the ICU admission after donor patients.