The Islamic banking sector which has developed rapidly in the last 50 years in the world is operating especially in the Organization of Islamic Cooperation (OIC) countries. Islamic trading methods have been used since the 6th century, and financial institutions that operate without interest in the economic relations in the modern world perform this task. In the modern sense, the first Islamic banking activities, which started in Egypt in 1963, compete with conventional banks in a striking way and have grown by an average of 20% over the last 50 years and now reach $ 2 trillion. The Islamic banking sector, which operates by risk sharing, partnership principle, is subject to real commercial transactions. Therefore, it is anticipated that the volume of the transactions carried out by banks operating in Islamic manner can increase investment and financing activities, specialization and trading volume in the OIC countries. The purpose of working in this light of information; The result of the increase in Islamic banking activities in the world is to investigate the causality relationship between GDP per capita GDP, Per Capita National Income (PCI), Human Development Index (HDI) and OIC Internal Trade Volume (OICOFTV) data. As a result of the causality test, it is understood that the development of the Islamic banking volume in the world has increased the GDP of the OIC countries. Likewise, the increase in the GDP of OIC countries increases the volume of Islamic banking in the world. It is understood that HDI has increased in OIC countries with the increase of Islamic banking volume. Moreover, the increase in the volume of Islamic banking led to the increase in the PCI countries in the OIC countries and the increase in the intra-organizational foreign trade volume of the OIC countries provided an increase in the volume of Islamic banking.