Yıl: 2018 Cilt: 21 Sayı: 2 Sayfa Aralığı: 240 - 251 Metin Dili: İngilizce DOI: 10.31086/tjgeri.2018240425 İndeks Tarihi: 05-07-2019

DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION

Öz:
Introduction: This study investigated differences in clinical features, types, etiology, andrisk factors for complications between young and older patients with skin and soft tissueinfections. Futhermore, age-related differences in healthcare-associated and complicatedinfections were identified.Materials and Method: This retrospective study included 206 skin and soft tissueinfection patients hospitalized during an 8-year period. Data were collected using a form:patients’ characteristics, clinical features, laboratory values, prior antibiotic use, causativemicroorganisms, and antibiotic treatment. For cases with clinically diagnosed, samples weretaken from the suspected infection sites. Gram staining, deep swab, deep tissue and bloodculture results were evaluated.Results: The incidence of diabetes mellitus was significantly higher among patientsaged ≥65 years. Among these old patients, Escherichia coli (11/31, 35.5%) and Pseudomonasaeruginosa (8/31, 25.8%) were the most frequently isolated pathogens. Approximately halfof the Staphylococcus aureus and Staphylococcus epidermidis strains isolated from patientswith health care-associated infection were resistant to methicillin (8/15, 53.3%), and thesepatients produced higher levels of extended-spectrum beta-lactamase. Venous insufficiency(p=0.008) and prior hospitalization (p=0.001) were identified as risk factors for complicationin patients aged ≥65. The median time- to -clinical response was 7 days in older patients withnon-complicated infection (p=0.007).Conclusion: Diabetes mellitus was the most common co-morbid factor in older patients.Risk factors for complication may differ by age. Gram-negative pathogens were morecommonly isolated in older patients. The time- to -clinical response was significantly longer inolder patients with non-complicated infection than young patients.
Anahtar Kelime:

Konular: Cerrahi

DERİ VE YUMUŞAK DOKU ENFEKSİYONLU GENÇ VE YAŞLI HASTALAR ARASINDA KLİNİK ÖZELLİKLER, TİP, ETİYOLOİ VE KOMPLİKE EDİCİ RİSK FAKTÖRLERİ AÇISINDAN FARKLILIKLAR

Öz:
Giriş: Bu çalışmada, deri ve yumuşak doku enfeksiyonu tanısı alan genç ve yaşlı hastalar arasında klinik özellikler, tip, etiyoloji ve komplike edici risk faktörleri açısından farklılıklar araştırıldı. Ayrıca sağlık bakımı ilişkili ve komplike deri ve yumuşak doku enfeksiyonlu hastalarda yaşla ilişkili farklılıklar belirlendi. Gereç ve Yöntem: Bu retrospektif çalışmaya sekiz yıllık süre içinde deri ve yumuşak doku enfeksiyonu tanısı alıp yatırılan 206 hasta alındı. Hastaların karakteristik ve klinik özelliklerini, laboratuvar değerlerini, öncesinde antibiyotik kullanımlarını, izole edilen etken mikroorganizmaları ve antibiyotik tedavilerini içeren veriler bir forma kaydedildi. Klinik olarak deri ve yumuşak doku enfeksiyonu tanısı koyulanların şüpheli enfeksiyon bölgelerinden örnekler alındı. Gram boyama, derin sürüntü, doku ve kan kültürleri değerlendirildi. Bulgular: Diabetes mellitus, 65 yaş ve üzerindeki hastalarda yüksekti. Bu yaşlı hastalar arasında Escherichia coli (11/31, %35,5) ve Pseudomonas aeruginosa (8/31, %25,8), en sık izole edilen patojenlerdi. Sağlık bakımı ilişkili hastalardan izole edilen Staphylococcus aureus ve Staphylococcus epidermidis suşlarının yaklaşık yarısı (8/15, %53,3) metisiline dirençliydi ve bu hastalarda genişlemiş spektrumlu beta laktamaz üretimi de yüksekti. Venöz yetmezlik (p=0.008) ve önceden hastanede yatış (p=0.001), 65 yaş ve üzerindeki hastalarda komplike edici risk faktörleri olarak belirlendi. Ortalama klinik yanıt alma zamanı, komplike olmayan yaşlı hastalarda ortalama 7 gündü (p=0.007). Sonuç: Diabetes mellitus, yaşlı hastalar arasında en yaygın komorbid faktördü. Komplike edici risk faktörlerinin yaşla ilişkili değişebildiği gözlendi. Yaşlı, deri ve yumuşak doku enfeksiyonlu hastalardan en sık izole edilen etkenler Gram-negatif patojenlerdi. Ortalama klinik yanıt alma zamanı, komplike olmayan yaşlı hastalarda gençlere göre anlamlı olarak yüksekti.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA HORUZ E, AYDEMİR H, PİŞKİN N, ATAKENT D, ÇELEBİ G, KÖKTÜRK F (2018). DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. , 240 - 251. 10.31086/tjgeri.2018240425
Chicago HORUZ Emre,AYDEMİR Hande,PİŞKİN Nihal,ATAKENT Deniz,ÇELEBİ Güven,KÖKTÜRK Fürüzan DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. (2018): 240 - 251. 10.31086/tjgeri.2018240425
MLA HORUZ Emre,AYDEMİR Hande,PİŞKİN Nihal,ATAKENT Deniz,ÇELEBİ Güven,KÖKTÜRK Fürüzan DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. , 2018, ss.240 - 251. 10.31086/tjgeri.2018240425
AMA HORUZ E,AYDEMİR H,PİŞKİN N,ATAKENT D,ÇELEBİ G,KÖKTÜRK F DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. . 2018; 240 - 251. 10.31086/tjgeri.2018240425
Vancouver HORUZ E,AYDEMİR H,PİŞKİN N,ATAKENT D,ÇELEBİ G,KÖKTÜRK F DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. . 2018; 240 - 251. 10.31086/tjgeri.2018240425
IEEE HORUZ E,AYDEMİR H,PİŞKİN N,ATAKENT D,ÇELEBİ G,KÖKTÜRK F "DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION." , ss.240 - 251, 2018. 10.31086/tjgeri.2018240425
ISNAD HORUZ, Emre vd. "DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION". (2018), 240-251. https://doi.org/10.31086/tjgeri.2018240425
APA HORUZ E, AYDEMİR H, PİŞKİN N, ATAKENT D, ÇELEBİ G, KÖKTÜRK F (2018). DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. Türk Geriatri Dergisi, 21(2), 240 - 251. 10.31086/tjgeri.2018240425
Chicago HORUZ Emre,AYDEMİR Hande,PİŞKİN Nihal,ATAKENT Deniz,ÇELEBİ Güven,KÖKTÜRK Fürüzan DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. Türk Geriatri Dergisi 21, no.2 (2018): 240 - 251. 10.31086/tjgeri.2018240425
MLA HORUZ Emre,AYDEMİR Hande,PİŞKİN Nihal,ATAKENT Deniz,ÇELEBİ Güven,KÖKTÜRK Fürüzan DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. Türk Geriatri Dergisi, vol.21, no.2, 2018, ss.240 - 251. 10.31086/tjgeri.2018240425
AMA HORUZ E,AYDEMİR H,PİŞKİN N,ATAKENT D,ÇELEBİ G,KÖKTÜRK F DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. Türk Geriatri Dergisi. 2018; 21(2): 240 - 251. 10.31086/tjgeri.2018240425
Vancouver HORUZ E,AYDEMİR H,PİŞKİN N,ATAKENT D,ÇELEBİ G,KÖKTÜRK F DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION. Türk Geriatri Dergisi. 2018; 21(2): 240 - 251. 10.31086/tjgeri.2018240425
IEEE HORUZ E,AYDEMİR H,PİŞKİN N,ATAKENT D,ÇELEBİ G,KÖKTÜRK F "DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION." Türk Geriatri Dergisi, 21, ss.240 - 251, 2018. 10.31086/tjgeri.2018240425
ISNAD HORUZ, Emre vd. "DIFFERENCES IN CLINICAL FEATURES, ETIOLOGY, TYPES, AND RISK FACTORS FOR COMPLICATIONS BETWEEN YOUNG AND OLDER PATIENTS WITH SKIN AND SOFT TISSUE INFECTION". Türk Geriatri Dergisi 21/2 (2018), 240-251. https://doi.org/10.31086/tjgeri.2018240425