Yıl: 2018 Cilt: 27 Sayı: 1 Sayfa Aralığı: 10 - 18 Metin Dili: İngilizce DOI: 10.4274/mirt.97659 İndeks Tarihi: 12-07-2019

Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests

Öz:
Objective: The aim of the present study was to compare the performance of positron emission tomography (PET) component of PET/computed tomography (CT) with new emerging PET/magnetic resonance (MR) of the same vendor. Methods: According to National Electrical Manufacturers Association NU2-07, five separate experimental tests were performed to evaluate the performance of PET scanner of General Electric GE company; SIGNATM model PET/MR and GE Discovery 710 model PET/CT. The main investigated aspects were spatial resolution, sensitivity, scatter fraction, count rate performance, image quality, count loss and random events correction accuracy. Results: The findings of this study demonstrated superior sensitivity (~ 4 folds) of PET scanner in PET/MR compared to PET/ CT system. Image quality test exhibited higher contrast in PET/MR (~ 9%) compared with PET/CT. The scatter fraction of PET/ MR was 43.4% at noise equivalent count rate (NECR) peak of 218 kcps and the corresponding activity concentration was 17.7 kBq/cc. Whereas the scatter fraction of PET/CT was found as 39.2% at NECR peak of 72 kcps and activity concentration of 24.3 kBq/cc. The percentage error of the random event correction accuracy was 3.4% and 3.1% in PET/MR and PET/CT, respectively. Conclusion: It was concluded that PET/MR system is about 4 times more sensitive than PET/CT, and the contrast of hot lesions in PET/MR was ~ 9% higher than PET/CT. These outcomes also emphasize the possibility to achieve excellent clinical PET images with low administered dose and/or a short acquisition time in PET/MR.
Anahtar Kelime:

Konular: Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme

PET/MR ve PET/BT Sistemlerinde PET Tarayıcının Performanslarının Değerlendirilmesi: NEMA Testleri

Öz:
Amaç: Bu çalışmada son yıllarda nükleer tıpta rutin uygulamaya giren pozitron emisyon tomografisi/manyetik rezonans (PET/ MR) görüntüleme sistemi ile PET/bilgisayarlı tomografi (BT) görüntüleme sistemlerinde ‘National Electrical Manufacturers Association’ (NEMA) testlerinin yapılması ve sonuçların karşılaştırılması amaçlandı. Yöntem: NEMA NU2-07 testlerinden uzaysal ayırma gücü, hassasiyet, saçılma fraksiyonu kayıp sayımlar ve rastgele olay ölçümleri, görüntü kalitesi, sayım kayıpları rastgele olay düzeltme doğruluğu olmak üzere beş ayrı deneysel çalışma yapıldı. Bulgular: Sensitivite testi sonuçları değerlendirildiğinde PET/MR sisteminin PET/BT sistemine göre yaklaşık 4 kat daha üstün olduğu bulundu. Görüntü kalitesi test sonuçlarından sıcak lezyon kontrastının PET/MR’da %9 daha yüksek olduğu bulundu. PET/MR scatter oranı gürültü eşdeğeri sayım hızı (NECR) 218 kcts ve aktivite konsantrasyonunun 17,7 kcts/cc olduğu durumda %43,4 bulundu. Buna karşılık PET/BT scatter oranı NECR 72 kcts ve aktivite konsantrasyonunun 24,3 kcts/cc olduğu durumda %39,2 bulundu. Tesadüfi hataları düzeltme doğruluğu PET/MR’da 3,4 ve PET/BT’de 3,1 bulundu. Sonuç: PET/MR’da sensitivite değerinin PET/BT’ye göre yaklaşık 4 kat daha yüksek olduğu, PET/MR’da sıcak lezyon kontrastının PET/BT’ye göre %9 daha yüksek olduğu ayrıca PET/MR’da PET görüntülerinin daha az aktivite miktarı/veya daha kısa çekim süresinde elde edilebileceği sonucuna varıldı.
Anahtar Kelime:

Konular: Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA DEMİR M, TOKLU T, ABUQBEITAH M, ÇETİN H, SEZGİN H, Yeyin N, SÖNMEZOĞLU K (2018). Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. , 10 - 18. 10.4274/mirt.97659
Chicago DEMİR MUSTAFA,TOKLU Türkay,ABUQBEITAH Mohammad,ÇETİN HÜSEYİN,SEZGİN H. Sezer,Yeyin Nami,SÖNMEZOĞLU Kerim Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. (2018): 10 - 18. 10.4274/mirt.97659
MLA DEMİR MUSTAFA,TOKLU Türkay,ABUQBEITAH Mohammad,ÇETİN HÜSEYİN,SEZGİN H. Sezer,Yeyin Nami,SÖNMEZOĞLU Kerim Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. , 2018, ss.10 - 18. 10.4274/mirt.97659
AMA DEMİR M,TOKLU T,ABUQBEITAH M,ÇETİN H,SEZGİN H,Yeyin N,SÖNMEZOĞLU K Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. . 2018; 10 - 18. 10.4274/mirt.97659
Vancouver DEMİR M,TOKLU T,ABUQBEITAH M,ÇETİN H,SEZGİN H,Yeyin N,SÖNMEZOĞLU K Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. . 2018; 10 - 18. 10.4274/mirt.97659
IEEE DEMİR M,TOKLU T,ABUQBEITAH M,ÇETİN H,SEZGİN H,Yeyin N,SÖNMEZOĞLU K "Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests." , ss.10 - 18, 2018. 10.4274/mirt.97659
ISNAD DEMİR, MUSTAFA vd. "Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests". (2018), 10-18. https://doi.org/10.4274/mirt.97659
APA DEMİR M, TOKLU T, ABUQBEITAH M, ÇETİN H, SEZGİN H, Yeyin N, SÖNMEZOĞLU K (2018). Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. Molecular Imaging and Radionuclide Therapy, 27(1), 10 - 18. 10.4274/mirt.97659
Chicago DEMİR MUSTAFA,TOKLU Türkay,ABUQBEITAH Mohammad,ÇETİN HÜSEYİN,SEZGİN H. Sezer,Yeyin Nami,SÖNMEZOĞLU Kerim Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. Molecular Imaging and Radionuclide Therapy 27, no.1 (2018): 10 - 18. 10.4274/mirt.97659
MLA DEMİR MUSTAFA,TOKLU Türkay,ABUQBEITAH Mohammad,ÇETİN HÜSEYİN,SEZGİN H. Sezer,Yeyin Nami,SÖNMEZOĞLU Kerim Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. Molecular Imaging and Radionuclide Therapy, vol.27, no.1, 2018, ss.10 - 18. 10.4274/mirt.97659
AMA DEMİR M,TOKLU T,ABUQBEITAH M,ÇETİN H,SEZGİN H,Yeyin N,SÖNMEZOĞLU K Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. Molecular Imaging and Radionuclide Therapy. 2018; 27(1): 10 - 18. 10.4274/mirt.97659
Vancouver DEMİR M,TOKLU T,ABUQBEITAH M,ÇETİN H,SEZGİN H,Yeyin N,SÖNMEZOĞLU K Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests. Molecular Imaging and Radionuclide Therapy. 2018; 27(1): 10 - 18. 10.4274/mirt.97659
IEEE DEMİR M,TOKLU T,ABUQBEITAH M,ÇETİN H,SEZGİN H,Yeyin N,SÖNMEZOĞLU K "Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests." Molecular Imaging and Radionuclide Therapy, 27, ss.10 - 18, 2018. 10.4274/mirt.97659
ISNAD DEMİR, MUSTAFA vd. "Evaluation of PET Scanner Performance in PET/MR and PET/CT Systems: NEMA Tests". Molecular Imaging and Radionuclide Therapy 27/1 (2018), 10-18. https://doi.org/10.4274/mirt.97659