Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay
Yıl: 2017 Cilt: 21 Sayı: 3 Sayfa Aralığı: 530 - 536 Metin Dili: İngilizce DOI: 10.12991/marupj.311818 İndeks Tarihi: 18-07-2019
Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay
Öz: The purpose of this study is to investigate the association between DNA damage and blood arsenic levels in individuals occupationally exposed to arsenic (As). A hundred-twenty exposed individuals from silver mining plate workers were monitored in the way of DNA damage in blood lymphocytes using comet assay (single cell gel electrophoresis, SSGE). The DNA damage levels were measured by BAB Bs Comet Assay system and As levels were analyzed by the atomic absorption spectrometer (AAS) system. The mean blood arsenic level was 17.03±10.85 µg/L. A statistically significant positive correlations were found between the arsenic levels and comet parameters (tail intensity, comet length and tail length) (r=0.360, r=0.334, r=0.259, respectively, p<0.01). Our results showed that exposure to arsenic may cause DNA damage in peripheral lymphocytes of Turkish silver mining plate workers.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | SOYLEMEZ E, KAYAALTI Z, KAYA AKYÜZLÜ D, TUTKUN E, Soylemezoglu T (2017). Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. , 530 - 536. 10.12991/marupj.311818 |
| Chicago | SOYLEMEZ Esma,KAYAALTI Zeliha,KAYA AKYÜZLÜ Dilek,TUTKUN Engin,Soylemezoglu Tulin Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. (2017): 530 - 536. 10.12991/marupj.311818 |
| MLA | SOYLEMEZ Esma,KAYAALTI Zeliha,KAYA AKYÜZLÜ Dilek,TUTKUN Engin,Soylemezoglu Tulin Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. , 2017, ss.530 - 536. 10.12991/marupj.311818 |
| AMA | SOYLEMEZ E,KAYAALTI Z,KAYA AKYÜZLÜ D,TUTKUN E,Soylemezoglu T Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. . 2017; 530 - 536. 10.12991/marupj.311818 |
| Vancouver | SOYLEMEZ E,KAYAALTI Z,KAYA AKYÜZLÜ D,TUTKUN E,Soylemezoglu T Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. . 2017; 530 - 536. 10.12991/marupj.311818 |
| IEEE | SOYLEMEZ E,KAYAALTI Z,KAYA AKYÜZLÜ D,TUTKUN E,Soylemezoglu T "Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay." , ss.530 - 536, 2017. 10.12991/marupj.311818 |
| ISNAD | SOYLEMEZ, Esma vd. "Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay". (2017), 530-536. https://doi.org/10.12991/marupj.311818 |
| APA | SOYLEMEZ E, KAYAALTI Z, KAYA AKYÜZLÜ D, TUTKUN E, Soylemezoglu T (2017). Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. Marmara Pharmaceutical Journal, 21(3), 530 - 536. 10.12991/marupj.311818 |
| Chicago | SOYLEMEZ Esma,KAYAALTI Zeliha,KAYA AKYÜZLÜ Dilek,TUTKUN Engin,Soylemezoglu Tulin Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. Marmara Pharmaceutical Journal 21, no.3 (2017): 530 - 536. 10.12991/marupj.311818 |
| MLA | SOYLEMEZ Esma,KAYAALTI Zeliha,KAYA AKYÜZLÜ Dilek,TUTKUN Engin,Soylemezoglu Tulin Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. Marmara Pharmaceutical Journal, vol.21, no.3, 2017, ss.530 - 536. 10.12991/marupj.311818 |
| AMA | SOYLEMEZ E,KAYAALTI Z,KAYA AKYÜZLÜ D,TUTKUN E,Soylemezoglu T Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. Marmara Pharmaceutical Journal. 2017; 21(3): 530 - 536. 10.12991/marupj.311818 |
| Vancouver | SOYLEMEZ E,KAYAALTI Z,KAYA AKYÜZLÜ D,TUTKUN E,Soylemezoglu T Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay. Marmara Pharmaceutical Journal. 2017; 21(3): 530 - 536. 10.12991/marupj.311818 |
| IEEE | SOYLEMEZ E,KAYAALTI Z,KAYA AKYÜZLÜ D,TUTKUN E,Soylemezoglu T "Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay." Marmara Pharmaceutical Journal, 21, ss.530 - 536, 2017. 10.12991/marupj.311818 |
| ISNAD | SOYLEMEZ, Esma vd. "Evaluation of Relationship Between Lymphocyte DNA Damages and Blood Arsenic Levels in Silver Mining Workers using Alkaline Comet Assay". Marmara Pharmaceutical Journal 21/3 (2017), 530-536. https://doi.org/10.12991/marupj.311818 |
