In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines

Ayşe Tansu KOPARAL (Eskişehir Teknik Üniversitesi)
Anadolu Journal of Educational Sciences International
7 1
Yıl: 2019 Cilt: 9 Sayı: 2 Sayfa Aralığı: 549 - 571 Metin Dili: İngilizce DOI: 10.18039/ajesi.577253 İndeks Tarihi: 25-12-2019

In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines

Öz:
The purpose of this study is to investigate the effects of gilaburu juice on cell viability (3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide, MTT) and angiogenesis (tubeformation assay) using different cell lines (human cancer cell lines A549, Caco-2, HeLa andnormal cell lines MDCK and HUVEC) in vitro. In addition, the genotoxic effects of gilaburu juiceis evaluated using COMET assay on HUVEC cells. Our results demonstrate that gilaburu juicecould inhibit the growth of Caco-2 and HeLa cancer cell lines, but could not significantly inhibitnormal cell lines and A549 cancer cell lines. It disrupted tube formation of HUVEC cells. Gilaburujuice appears to have no genotoxic potential to the DNA of HUVEC cells. The results obtained inthis study confirm the potential application of commercial gilaburu juice as a functional food inprevention of cancer.
Anahtar Kelime:

Konular: Eğitim, Eğitim Araştırmaları
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Koparal A (2019). In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. , 549 - 571. 10.18039/ajesi.577253
Chicago Koparal Ayse In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. (2019): 549 - 571. 10.18039/ajesi.577253
MLA Koparal Ayse In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. , 2019, ss.549 - 571. 10.18039/ajesi.577253
AMA Koparal A In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. . 2019; 549 - 571. 10.18039/ajesi.577253
Vancouver Koparal A In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. . 2019; 549 - 571. 10.18039/ajesi.577253
IEEE Koparal A "In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines." , ss.549 - 571, 2019. 10.18039/ajesi.577253
ISNAD Koparal, Ayse. "In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines". (2019), 549-571. https://doi.org/10.18039/ajesi.577253
APA Koparal A (2019). In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. Anadolu Journal of Educational Sciences International , 9(2), 549 - 571. 10.18039/ajesi.577253
Chicago Koparal Ayse In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. Anadolu Journal of Educational Sciences International 9, no.2 (2019): 549 - 571. 10.18039/ajesi.577253
MLA Koparal Ayse In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. Anadolu Journal of Educational Sciences International , vol.9, no.2, 2019, ss.549 - 571. 10.18039/ajesi.577253
AMA Koparal A In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. Anadolu Journal of Educational Sciences International . 2019; 9(2): 549 - 571. 10.18039/ajesi.577253
Vancouver Koparal A In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines. Anadolu Journal of Educational Sciences International . 2019; 9(2): 549 - 571. 10.18039/ajesi.577253
IEEE Koparal A "In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines." Anadolu Journal of Educational Sciences International , 9, ss.549 - 571, 2019. 10.18039/ajesi.577253
ISNAD Koparal, Ayse. "In Vitro Evaluation of Gilaburu (Viburnum Opulus L. ) Juice on Different Cell Lines". Anadolu Journal of Educational Sciences International 9/2 (2019), 549-571. https://doi.org/10.18039/ajesi.577253
Sayfa Oluşturulma Tarihi
17-04-2024 12:44

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