The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study
Yıl: 2018 Cilt: 7 Sayı: 2 Sayfa Aralığı: 47 - 52 Metin Dili: İngilizce İndeks Tarihi: 25-10-2019
The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study
Öz: Aim: Acute respiratory infections are one of the diseases in which antibiotics are inappropriately used. Our study aim was to define the efficacy and safety of the rapid antigen detection test in decreasing the inappropriate use of antibiotics in adults. Methods: This was a retrospective study on patients over 15 years of age who came to our clinic because of sore throat from September 2016 to 2017. Data on culture, rapid antigen detection test results, and the prescribed drugs were recorded from their files and were expressed as frequencies. Statistical analyses were performed by the Chi-square test and Student’s t-test, with p <0.05 accepted as statistically significant. Results: Among a total of 2426 patients, the rapid antigen detection test and culture results had a perfect fit (κ=0.911) and had no statistically significant differences (p=0.125). Using culture as the standard, the rapid antigen detection test had a sensitivity of 86.4%, specificity of 99.9%, positive predictive value of 97.4%, negative predictive value of 99.2%, and correct awareness rate of 99.1%. Conclusion: The use of rapid antigen detection test in cases with pharyngitis could make antibiotic prescription safe and appropriate.
Anahtar Kelime: Konular:
Erişkinlerde Hızlı Antijen Testinin Etkinliği ve Güvenirliği: Retrospektif Bir Çalışma
Öz: Amaç: Akut solunum yolu enfeksiyonları, antibiyotiklerin uygunsuz şekilde kullanıldığı hastalıklardan biridir. Çalışmamızın amacı, yetişkinlerde uygun olmayan antibiyotik kullanımını azaltmada hızlı antijen saptama testinin etkinliğini ve güvenilirliğini araştırmaktır. Yöntem: Bu çalışma Eylül 2016- 2017 tarihleri arasında kliniğimize boğaz ağrısı nedeniyle gelen 15 yaş üstü hastaların retrospektif olarak tarandığı bir çalışmadır. Kültür, hızlı antijen tespit testi sonuçları ve reçete edilen ilaçlarla ilgili veriler dosyalarından kaydedildi. Gerekli olan istatistiksel analizler yapıldı (Ki-kare testi ve Student's t-testi). p<0,05 istatistiksel olarak anlamlı kabul edildi. Bulgular: Toplam 2426 hasta arasında hızlı antijen tespit testi ve kültür sonuçları mükemmel uyum sağlamış (κ=0,911) ve istatistiksel olarak anlamlı fark (p=0,125) göstermedi. Hızlı antijen tespit testinin duyarlılığı %86,4, özgüllüğü %99,9, pozitif prediktif değeri %97,4, negatif prediktif değeri %99,2 ve doğru farkındalık oranı %99,1 idi. Sonuç: Boğaz ağrısı ile gelen olgularda hızlı antijen tespit testinin kullanımı ve sonuca göre antibiyotik reçetelemesi uygunsuz antibiyotik kullanımını azaltacaktır.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ÖZTÜRK G, Toprak D (2018). The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. , 47 - 52. |
| Chicago | ÖZTÜRK Güzin Zeren,Toprak Dilek The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. (2018): 47 - 52. |
| MLA | ÖZTÜRK Güzin Zeren,Toprak Dilek The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. , 2018, ss.47 - 52. |
| AMA | ÖZTÜRK G,Toprak D The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. . 2018; 47 - 52. |
| Vancouver | ÖZTÜRK G,Toprak D The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. . 2018; 47 - 52. |
| IEEE | ÖZTÜRK G,Toprak D "The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study." , ss.47 - 52, 2018. |
| ISNAD | ÖZTÜRK, Güzin Zeren - Toprak, Dilek. "The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study". (2018), 47-52. |
| APA | ÖZTÜRK G, Toprak D (2018). The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. Eurasian Journal of Family Medicine, 7(2), 47 - 52. |
| Chicago | ÖZTÜRK Güzin Zeren,Toprak Dilek The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. Eurasian Journal of Family Medicine 7, no.2 (2018): 47 - 52. |
| MLA | ÖZTÜRK Güzin Zeren,Toprak Dilek The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. Eurasian Journal of Family Medicine, vol.7, no.2, 2018, ss.47 - 52. |
| AMA | ÖZTÜRK G,Toprak D The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. Eurasian Journal of Family Medicine. 2018; 7(2): 47 - 52. |
| Vancouver | ÖZTÜRK G,Toprak D The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study. Eurasian Journal of Family Medicine. 2018; 7(2): 47 - 52. |
| IEEE | ÖZTÜRK G,Toprak D "The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study." Eurasian Journal of Family Medicine, 7, ss.47 - 52, 2018. |
| ISNAD | ÖZTÜRK, Güzin Zeren - Toprak, Dilek. "The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study". Eurasian Journal of Family Medicine 7/2 (2018), 47-52. |
