Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu
Yıl: 2019 Cilt: 25 Sayı: 1 Sayfa Aralığı: 40 - 44 Metin Dili: Türkçe DOI: 10.14744/epilepsi.2018.30092 İndeks Tarihi: 01-11-2019
Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu
Öz: Frontotemporal lob dejenerasyonu sendromlarında nöbetler hem klinik fenotip hem de nöropatolojiye göre heterojen bir grup bozukluğu kapsamaktadır. Her ne kadar frontotemporal lob dejenerasyonu sendromlarında elektroensefalografi anormal olsa da, epileptik nöbetler nadiren rapor edilmiştir. Demans patogenezinin daha iyi anlaşılması, epileptogenezin mekanizmalarına ışık tutabilir ve nöbet tedavisine daha rasyonel yaklaşımları kolaylaştırabilir. Demans sendromlarında nöbetlerin tedavisi halen ampiriktir. Epilepsia parsiyalis kontinua “devamlı olan” bir nöbet tipi olarak 2001 ILAE sınıflamasında yer almaktadır. 2017 ILAE sınıflamasına göre hastamızın nöbeti fokal başlangıçlı, bilincin korunduğu, fokal motor klonik nöbet olarak tanımlanmıştır. Yeni başlayan Epilepsia parsiyalis kontinua progresif hastalığın genelde kötü habercisidir. Ayrıca altta yatan sebebe bakılmaksızın kombine yüksek doz antiepileptiklere yanıt vermemesi Epilepsia parsiyalis kontinuanın kötü prognostik özelliğidir.
Anahtar Kelime: Konular:
A Case of Frontotemporal Dementia with Epilepsia Partialis Continua Responding to Lacosamide Treatment
Öz: Seizures may occur in frontotemporal lobar degeneration syndromes as an element of a heterogeneous group of disorders, according to both clinical phenotype and neuropathology. Although electroencephalography results are abnormal in frontotemporal lobar degeneration syndromes, epileptic seizures are rarely reported. A better understanding of the pathogenesis of dementia may shed light on the mechanisms of epileptogenesis and may facilitate more rational approaches to seizure treatment. The treatment of seizures in dementia syndromes is still empiric. Epilepsia partialis continua (EPC) is included in the 2001 International League Against Epilepsy (ILAE) classification as a continuous type of seizure. According to the 2017 ILAE classification, the present patient’s seizure was defined as a focal onset, preserved consciousness, focal motor, clonic seizure. The onset of epilepsia partialis continua is usually a bad predictor of progressive disease. Furthermore, there is often a failure to respond to combined high dose antiepileptics, regardless of the underlying cause.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | DİNÇ Y, ÇELİK AKDAĞ G (2019). Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. , 40 - 44. 10.14744/epilepsi.2018.30092 |
| Chicago | DİNÇ Yasemin,ÇELİK AKDAĞ Gönül Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. (2019): 40 - 44. 10.14744/epilepsi.2018.30092 |
| MLA | DİNÇ Yasemin,ÇELİK AKDAĞ Gönül Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. , 2019, ss.40 - 44. 10.14744/epilepsi.2018.30092 |
| AMA | DİNÇ Y,ÇELİK AKDAĞ G Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. . 2019; 40 - 44. 10.14744/epilepsi.2018.30092 |
| Vancouver | DİNÇ Y,ÇELİK AKDAĞ G Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. . 2019; 40 - 44. 10.14744/epilepsi.2018.30092 |
| IEEE | DİNÇ Y,ÇELİK AKDAĞ G "Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu." , ss.40 - 44, 2019. 10.14744/epilepsi.2018.30092 |
| ISNAD | DİNÇ, Yasemin - ÇELİK AKDAĞ, Gönül. "Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu". (2019), 40-44. https://doi.org/10.14744/epilepsi.2018.30092 |
| APA | DİNÇ Y, ÇELİK AKDAĞ G (2019). Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. Epilepsi, 25(1), 40 - 44. 10.14744/epilepsi.2018.30092 |
| Chicago | DİNÇ Yasemin,ÇELİK AKDAĞ Gönül Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. Epilepsi 25, no.1 (2019): 40 - 44. 10.14744/epilepsi.2018.30092 |
| MLA | DİNÇ Yasemin,ÇELİK AKDAĞ Gönül Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. Epilepsi, vol.25, no.1, 2019, ss.40 - 44. 10.14744/epilepsi.2018.30092 |
| AMA | DİNÇ Y,ÇELİK AKDAĞ G Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. Epilepsi. 2019; 25(1): 40 - 44. 10.14744/epilepsi.2018.30092 |
| Vancouver | DİNÇ Y,ÇELİK AKDAĞ G Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu. Epilepsi. 2019; 25(1): 40 - 44. 10.14744/epilepsi.2018.30092 |
| IEEE | DİNÇ Y,ÇELİK AKDAĞ G "Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu." Epilepsi, 25, ss.40 - 44, 2019. 10.14744/epilepsi.2018.30092 |
| ISNAD | DİNÇ, Yasemin - ÇELİK AKDAĞ, Gönül. "Lakozamid Tedavisine Yanıtlı Frontotemporal Demansa Bağlı Epilepsia Parsiyalis Kontinua Olgusu". Epilepsi 25/1 (2019), 40-44. https://doi.org/10.14744/epilepsi.2018.30092 |
