Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension

CALIK, Mustafa; ÖZDEMİR, Levent; SÖKMEN, ERDOĞAN

Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension

Erdoğan SÖKMEN, (Kırşehir Ahi Evran Üniversitesi Eğitim ve Araştırma Hastanesi)

Levent ÖZDEMİR, (Kırşehir Ahi Evran Üniversitesi Eğitim ve Araştırma Hastanesi)

Mustafa ÇELİK (Kırşehir Ahi Evran Üniversitesi Eğitim ve Araştırma Hastanesi)

Bozok Tıp Dergisi

1 1

Yıl: 2019 Cilt: 9 Sayı: 2 Sayfa Aralığı: 112 - 119 Metin Dili: İngilizce İndeks Tarihi: 28-01-2020

Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension

Öz:

Background and Aim: Non-dipping circadian pattern and increased aortic stiffness have been linked toincreased morbidity and mortality in patients with hypertension (HT). Our aim in the present study wasto assess whether presystolic wave (PSW) velocity measured by Doppler transthoracic echocardiography(TTE) on left ventricular outflow tract (LVOT) had relationship with circadian pattern and the aortic stiffnessparameters assessed by TTE.Methods: A total of 140 newly-diagnosed essential HT patients admitting to the cardiology outpatientpolyclinic were consecutively included. Data regarding physical examination, laboratory analysis, TTE,and ambulatory blood pressure monitoring (ABPM) were obtained retrospectively from medical records.Patients were divided into dipper (n=75) and non-dipper (n=65) groups on the basis of ABPM. Relationshipof PSW velocity with circadian pattern and aortic stiffness was evaluated.Results: Peak PSW velocity was similar between dipper and non-dipper HT subgroups. Spearman’scorrelation analysis showed a positive correlation of PSW velocity with aortic stiffness index (r=0.286;p=0.007), transmitral A velocity (r=0.260; p=0.017), E/A ratio (r=-0.265; p=0.015), and lateral E’ velocity(r=-0.279; p=0.013). In multivariate lineer regression model, aortic stiffness index (β=0.525, p<0.001), age(β=0.239, p=0.009), lateral E/E’ ratio (β=0.636, p<0.001) and E/A ratio (β=-0.503, p<0.001) emerged assignificant predictors of PSW velocity.Conclusion: Peak velocity of PSW on LVOT, if present, may provide information about the status of aorticstiffness and LV compliance assessed by TTE. However, PSW velocity is not useful in the prediction ofcircadian blood pressure pattern in newly-diagnosed essential HT patients.

Anahtar Kelime:

YENİ TANI ESANSİYEL HİPERTANSİYON HASTALARINDA PRESİSTOLİK DALGA AORTİK SERTLİK DERECESİNİ ÖNGÖRDÜREBİLMEKTE, FAKAT SİRKADİYEN KAN BASINCI PATERNİNİ ÖNGÖREMEMEKTEDİR

Öz:

Arka plan ve Amaç: Hipertansiyon (HT) hastalarında non-dipping sirkadiyen patern ile artmış aortik sertlik derecesi, morbidite ve mortalite artışı ile ilişkilidir. Bu çalışmadaki amacımız sol ventrikül çıkım yolu (SVÇY) üzerinde transtorasik doppler ekokardiyografi (TTE) ile ölçümlenen presistolik dalganın (PSD), TTE ile ölçülen aortik sertlik parametreleri ile ilişkisinin olup olmadığının değerlendirilmesidir. Metot: Kardiyoloji polikliniğine başvuran ve yeni hipertansiyon teşhisi konan ardışık 140 hasta çalışmaya dahil edildi. Fizik muayene, laboratuar analizi, TTE ve ambülatuar kan basınç monitörizasyonu (AKBM) ile ilişkili veriler arşiv taraması yoluyla retrospektif olarak elde edildi. Hastalar, AKBM sonuçlarına göre dipper (75 hasta) ve non-dipper (65 hasta) şeklinde alt gruplara ayrıldı. PSD velositesi ile sirkadiyen patern ve aortik sertlik arasındaki ilişki incelendi. Bulgular: PSD tepe velositesi, dipper ve non-dipper HT hasta alt grupları arasında benzerdi. Spearman kore- lasyon analizinde PSD ile aortik sertlik indeksi (r=0.286; p=0.007), transmitral A velositesi (r=0.260; p=0.017), E/A oranı (r= -0.265; p=0.015) ve lateral E' velositesi (r= -0.279; p=0.013) arasında anlamlı korelasyon izlendi. Çok değişkenli lineer regresyon analizinde aortik sertlik indeksinin (β =0.525, p<0.001), yaşın (β =0.239, p=0.009), lateral E/E’ oranının (β =0.636, p<0.001) ve E/A oranının (β =-0.503, p<0.001), PSD velositesi için önemli öngördürücüler olduğu tespit edilmiştir. Sonuç: Şayet mevcut ise, yeni tanı hipertansiyon hastalarında SVÇY üzerinden ölçülen PSD velositesi, TTE ile değerlendirilen aortik sertlik derecesi ve sol ventrikül kompliansı ile ilgili bilgi sağlayabilmekte olup sirkadi- yen kan basıncı paternini öngördürmede yarar sağlamamaktadır.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SÖKMEN E, ÖZDEMİR L, CALIK M (2019). Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. , 112 - 119.
Chicago	SÖKMEN ERDOĞAN,ÖZDEMİR Levent,CALIK Mustafa Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. (2019): 112 - 119.
MLA	SÖKMEN ERDOĞAN,ÖZDEMİR Levent,CALIK Mustafa Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. , 2019, ss.112 - 119.
AMA	SÖKMEN E,ÖZDEMİR L,CALIK M Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. . 2019; 112 - 119.
Vancouver	SÖKMEN E,ÖZDEMİR L,CALIK M Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. . 2019; 112 - 119.
IEEE	SÖKMEN E,ÖZDEMİR L,CALIK M "Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension." , ss.112 - 119, 2019.
ISNAD	SÖKMEN, ERDOĞAN vd. "Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension". (2019), 112-119.

APA	SÖKMEN E, ÖZDEMİR L, CALIK M (2019). Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. Bozok Tıp Dergisi, 9(2), 112 - 119.
Chicago	SÖKMEN ERDOĞAN,ÖZDEMİR Levent,CALIK Mustafa Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. Bozok Tıp Dergisi 9, no.2 (2019): 112 - 119.
MLA	SÖKMEN ERDOĞAN,ÖZDEMİR Levent,CALIK Mustafa Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. Bozok Tıp Dergisi, vol.9, no.2, 2019, ss.112 - 119.
AMA	SÖKMEN E,ÖZDEMİR L,CALIK M Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. Bozok Tıp Dergisi. 2019; 9(2): 112 - 119.
Vancouver	SÖKMEN E,ÖZDEMİR L,CALIK M Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension. Bozok Tıp Dergisi. 2019; 9(2): 112 - 119.
IEEE	SÖKMEN E,ÖZDEMİR L,CALIK M "Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension." Bozok Tıp Dergisi, 9, ss.112 - 119, 2019.
ISNAD	SÖKMEN, ERDOĞAN vd. "Presystolic Wave Velocity May Predict Aortic Stiffness But Not Circadian Blood Pressure Pattern In Patients With Newly Diagnosed Essential Hypertension". Bozok Tıp Dergisi 9/2 (2019), 112-119.