Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables

KURT, Emine Eda; TUNCAY, FİGEN; BORMAN, Pınar; ERGÜN, Ufuk; KAYGISIZ, Ferda

Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables

Figen TUNCAY, (Ahi Evran University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Kırşehir, Turkey)

Ferda KAYGISIZ, (Physical Medicine and Rehabilitation, Ankara Education Research Hospital, Ankara, Turkey)

Pınar BORMAN, (Department of Physical Medicine and Rehabilitation, Medicine Faculty of Hacettepe University, Ankara, Turkey)

Emine Eda KURT, (Ahi Evran University Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Kırşehir, Turkey)

Ufuk ERGÜN (Department of Neurology, Ankara Education Research Hospital, Ankara, Turkey)

Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi

5 0

Yıl: 2017 Cilt: 20 Sayı: 1 Sayfa Aralığı: 16 - 23 Metin Dili: İngilizce İndeks Tarihi: 03-02-2020

Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables

Öz:

Objective: The aim of this study was to evaluate the the quality of life by a specificQuality of life (QoL) instrument and to determine the related clinical variables with QoL status inpatients with definite Multiple Sclerosis (MS). Material and Methods: Thirty-two MS patients witha mean age of 39±8.7 years were included in this study. Demographic and clinical charcteristics ofthe patients were recorded. QoL was assessed by Multiple Sclerosis International Quality of Life(MusiQoL) scale. Disability, ambulation, coping with stress, depression, anxiety, fatigue and painwere determined respectively by EDSS (Expanded Disability Status Scale), Functional AmbulationClassification (FAC), Coping with the Stress Scale (CWSS), Beck Depression scale (BDS), Beck anxietyscale (BAS), while pain and fatique was determined by Visual Analogue Scale (VAS) pain andfatigue instruments. Results: There were 25 female and 7 male patients with mean disease durationof 8.7±6.7 years and mean score of MusiQoL of 56.5±12.35. Negative correlations were found betweenMusiQoL with disease duration (r= -0.565 p=0.001), BDS (r=-0.459; p=0.008), BAS (r=-0.568;p=0.038), EDSS (r=-0.708; p= 0.021) and VAS fatigue (r=-0.451; p=0.039). Positive correlationswere found between MusiQoL with FAC score (r=0.424; p=0.01) and CWSS (r=0.531; p=0.002).There were no statistically significant correlation between MusiQoL and VAS pain (p>0.05).Conclusion: In this study, it was demonstrated that QoL is significantly associated with depression,anxiety, fatigue, ambulation level and the ability to cope with stress. MS symptoms and clinicalvariables have a negative impact on patients’ QoL. In this study, we emphasize the need for registrationand evaluation of clinical variables in order to improve QoL in patients suffering from MS.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp Rehabilitasyon

Multipl Sklerozlu Hastaların Hayat Kalitesi: İlişkili Klinik Değişkenler

Öz:

Amaç: Bu çalışmanın amacı Multipl Skleroz (MS) tanısı olan hastalarda hastalığa spesifik bir hayat kalitesi değerlendirme ölçeği ile yaşam kalitesini değerlendirmek ve yaşam kalitesi ile klinik değişkenler arasındaki ilişkiyi incelemektir. Gereç ve Yöntemler: Yaş ortalaması 39±8,7 yıl olan 32 MS’li hasta çalışmaya dahil edildi. Demografik ve klinik özellikleri kaydedildi. Yaşam kalitesi Multıple Skleroz Yaşam Kalite İndeksi (MSYKİ) ile değerlendirildi. Disabilite, ambulasyon, stresle başa çıkma, depresyon, anksiyete, yorgunluk ve ağrı, sırasıyla Genişletilmiş Özürlülük Durum Ölçeği (GÖDÖ), Fonksiyonel Ambulasyon Skalası (FAS), Stresle Başa Çıkma Ölçeği (SBÇÖ), Beck Depresyon Skalası (BDS), Beck Anksiyete Skalası (BAS) ile değerlendirilirken, ağrı ve yorgunluk Görsel Analog Skala (GAS) ile değerlendiridi. Bulgular: 25 kadın, 7 erkek hastanın hastalık süresi ortalama 8.7±6.7 yıl ve ortalama MSYKİ skoru 56.5±12.35 idi. MSYKİ skoru ile hastalık süresi (r= - 0,565 p=0,001), BDS (r= -0,459 p=0,008), BAS ( r=-0,568 p=0,038), GÖDÖ (r=-0,708 p= 0,021) ve VAS yorgunluk (r=-0,451 p=0.039) arasında negatif yönde anlamlı korelasyon tespit edildi. MSYKİ ile FAS skoru (r=0,424 p=0,01) ve SBÇÖ (r=0,531 p=0,002) skorları arasında da pozitif yönlü anlamlı korelasyon tespit edildi. MSYKİ skoru ile VAS ağrı skoru arasında korelasyon saptanmadı (p>0,05). Sonuç: Bu çalışmada yaşam kalitesinin, depresyon, anksiyete, yorgunluk, ambulasyon seviyesi, stres ile başa çıkma becerisi ilişkili olduğu gösterilmiştir. MS semptomları ve klinik değişkenlerinin hastaların yaşam kalitesi üzerinde negatif etkileri vardır. Biz bu çalışmada MS li hastalarda yaşam kalitesinin arttırılabilmesi için klinik değişkenlerin kayıt edilmesi ve değerlendirilmesinin gerekliliğini vurgulamayı amaçladık.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp Rehabilitasyon

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	TUNCAY F, KAYGISIZ F, BORMAN P, KURT E, ERGÜN U (2017). Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. , 16 - 23.
Chicago	TUNCAY FİGEN,KAYGISIZ Ferda,BORMAN Pınar,KURT Emine Eda,ERGÜN Ufuk Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. (2017): 16 - 23.
MLA	TUNCAY FİGEN,KAYGISIZ Ferda,BORMAN Pınar,KURT Emine Eda,ERGÜN Ufuk Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. , 2017, ss.16 - 23.
AMA	TUNCAY F,KAYGISIZ F,BORMAN P,KURT E,ERGÜN U Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. . 2017; 16 - 23.
Vancouver	TUNCAY F,KAYGISIZ F,BORMAN P,KURT E,ERGÜN U Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. . 2017; 16 - 23.
IEEE	TUNCAY F,KAYGISIZ F,BORMAN P,KURT E,ERGÜN U "Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables." , ss.16 - 23, 2017.
ISNAD	TUNCAY, FİGEN vd. "Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables". (2017), 16-23.

APA	TUNCAY F, KAYGISIZ F, BORMAN P, KURT E, ERGÜN U (2017). Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, 20(1), 16 - 23.
Chicago	TUNCAY FİGEN,KAYGISIZ Ferda,BORMAN Pınar,KURT Emine Eda,ERGÜN Ufuk Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi 20, no.1 (2017): 16 - 23.
MLA	TUNCAY FİGEN,KAYGISIZ Ferda,BORMAN Pınar,KURT Emine Eda,ERGÜN Ufuk Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, vol.20, no.1, 2017, ss.16 - 23.
AMA	TUNCAY F,KAYGISIZ F,BORMAN P,KURT E,ERGÜN U Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi. 2017; 20(1): 16 - 23.
Vancouver	TUNCAY F,KAYGISIZ F,BORMAN P,KURT E,ERGÜN U Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi. 2017; 20(1): 16 - 23.
IEEE	TUNCAY F,KAYGISIZ F,BORMAN P,KURT E,ERGÜN U "Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables." Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, 20, ss.16 - 23, 2017.
ISNAD	TUNCAY, FİGEN vd. "Quality of Life in Patients with Multiple Sclerosis: Relationship with Clinical Variables". Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi 20/1 (2017), 16-23.