Çiğdem ÇİLİNGİROĞLU
(Clinics of Physical Medicine and Rehabilitation, Health Sciences University Antalya Training and Research Hospital, Antalya, Turkey)
Meral BİLGİLİSOY FİLİZ
(Clinics of Physical Medicine and Rehabilitation, Health Sciences University Antalya Training and Research Hospital, Antalya, Turkey)
İLHAN SEZER
(Clinics of Rheumatology, Health Sciences University Antalya Training and Research Hospital, Antalya, Turkey)
Yıl: 2018Cilt: 21Sayı: 3ISSN: 1309-3843 / 1307-7384Sayfa Aralığı: 147 - 149İngilizce

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Melorheostosis: A Rare Disease
Melorheostosis is a rare nongenetic developmental anomaly first described in 1922 byLeri and Joanny. Its etiology is unknown. Patients present at any age, and both sexes are affectedequally. Onset is usually insidious, with pain, stiffness and limitation of motion at the affected areas.The characteristic radiographic appearance consists of irregular hyperostotic changes of the cortex,generally on one side of the bone, resembling melted wax dripping down one side of a candle. Thereis usually a demarcation line between the affected and normal bone. Dense, sclerotic linear areasare seen mainly in the cortex but also extending into the cancellous bone. Melorheostosis affectsmainly the long bones of the upper and lower limbs, but also the short bones of the hand and footand, rarely, the axial skeleton may be affected. Bone scintigraphy is positive and shows moderatelyincreased uptake of tracer in all three phases. Computed tomography and magnetic resonance imagingcan further characterize the lesion, but rarely contribute to the diagnosis. Treatment of thischronic condition consists of conservative therapies or surgical soft-tissue procedures and even, invery severe cases, amputation. In this case report, a 53 years old male patient with pain and morningstifness in his left hand for 6 months who has been diagnosed as melorheostosis by radiographicappearence is presented.
Fen > Tıp > Genel ve Dahili Tıp
Fen > Tıp > Rehabilitasyon
Dergititle.paper.fact_presentationErişime Açık
  • Freyschmidt J. Melorheostosis: a review of 23 cases. Eur Radiol. 2001;11:474-9.
  • Greenspan A. Sclerosing bone dysplasias--a target-site approach. Skeletal Radiol. 1991;20: 561-83.
  • Fryns JP, Pedersen JC, Vanfleteren L, et al. Melorheostosis in a 3-year-old girl. Acta Paediatr Belg. 1980;33:185-7.
  • Suresh S, Muthukumar T, Saifuddin A. Classical and unusual imaging appearances of melorheostosis. Clin Radiol. 2010;65:593- 600.
  • Saadallaoui Ben Hamida K, Ksontini I, Rahali H, et al. Atypical form of melorheostosis improved by pamidronate. Tunis Med. 2009;87:204-6.
  • Bansal A. The dripping candle wax sign. Radiology. 2008;246:638-40.
  • Donáth J, Poór G, Kiss C, et al. Atypical form of active melorheostosis and its treatment with bisphosphonate. Skeletal Radiol. 2002;31: 709-13.
  • Salman Monte TC, Rotés Sala D, Blanch Rubió J, et al. Melorheostosis, a case report. Reumatol Clin. 2011;7:346-8.
  • Gagliardi GG, Mahan KT. Melorheostosis: a literature review and case report with surgical considerations. J Foot Ankle Surg. 2010;49: 80-5.
  • Fernandes CH, Nakachima LR, Santos JB, et al. Melorheostosis of the thumb and trapezium bone. Hand (N Y). 2011;6:80-4.
  • Garver P, Resnick D, Haghighi P, et al. Melorheostosis of the axial skeleton with associated fibrolipomatous lesions. Skeletal Radiol. 1982;9:41-4.
  • Khurana JS, Ehara S, Rosenberg AE, et al. Case report 510: melorheostosis of ilium, femur, and adjacent soft tissues. Skeletal Radiol. 1988;17:539-41.
  • Resnick D, Niwayama G. Enostosis, hyperostosis, and periostitis. In: Resnick E, ed. Diagnosis of Bone and Joint Disorders. 3rd ed. Vol. 6. Philadelphia: Saunders; 1995. p.4396-466.
  • Salmanzadeh A, Pomeranz SJ,Ramsingh PS, et al. Radiological case of the month: melorheostosis of the left foot. Appl Radiol. 1998;27:36-8.
  • Motimaya AM, Meyers SP. Melorheostosis involving the cervical and upper thoracic spine: radiographic, CT, and MR imaging findings. AJNR Am J Neuroradiol. 2006;27:1198-200.
  • Rozencwaig R, Wilson MR, McFarland GB Jr. Melorheostosis. Am J Orthop (Belle Mead NJ). 1998;26:83-9.

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