Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury
Yıl: 2018 Cilt: 21 Sayı: 3 Sayfa Aralığı: 143 - 146 Metin Dili: İngilizce DOI: 10.31609/jpmrs.2017-54924 İndeks Tarihi: 04-02-2020
Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury
Öz: Orthostatic hypotension (OH) is an important clinical issue that may adversely affectthe rehabilitation process in patients with spinal cord injury (SCI). In some clinical situations whereOH is nonresponsive to non-pharmacological approaches, it may be beneficial to use midodrine forthe treatment of OH, which is a potent vasoconstrictive agent. A 62-year-old male patients with C4AIS C chronic spinal cord injury, he have OH associated with spinal cord injury admitted to hospitalfor the long term rehabilitative care. Rehabilitation program couldn’t be maintained as a resultof OH. Midodrine therapy was started to remove the OH. OH was completely improved withmidodrine therapy and the patient was finally able to sit. During the treatment, rate of AutonomicDysreflexia (AD) was increased, hence, the midodrin dosage was lowered to the level at which theAD was at least seen, and the treatment continued. The patient then was discharged from the hospitalat a wheelchair-dependent level. The midodrine was observed to be effective for the treatmentof OH in patients with SCI. AD, however, should be kept in mind that its frequency may increasesas a side effect of midodrine therapy.
Anahtar Kelime: Konular:
Omurilik Yaralanmasına Bağlı Ortostatik Hipotansiyonlu Bir Hastada Midodrin Tedavisi
Öz: Ortostatik hipotansiyon (OH), omurilik yaralanmalı (OY) hastalarda, rehabilitasyon sürecini olumsuz yönde etkileyebilecek önemli bir sorundur. OH’nun non-farmakolojik yaklaşımlara yanıtsız olduğu bazı klinik durumlarda, tedaviye güçlü bir vazokonstrüktif ajan olan Midodrinin eklenmesi OH tedavisinde faydalı olabilmektedir. Altmışiki yaşında C4 AIS C kronik spinal kord yaralanması olan erkek hastanın, OY’na bağlı gelişmiş olan OH’unun rehabilitasyonu olumsuz yönde etkilediği ve rehabilitasyon programında ilerleme kaydedilemediği görüldü. OH’nu ortadan kaldırmak amacıyla hastaya Midodrin tedavisi başlandı. Midodrin tedavisiyle OH tamamen kayboldu ve hasta oturabilir pozisyonu sağlayabildi. Midodrine bağlı otonomik disrefleksi (OD) sıklığı arttığından dolayı, midodrinin dozu, OD’nin en az görüldüğü seviyeye düşürülerek tedaviye devam edildi. Hasta tekerlekli sandalye seviyesine getirildi ve taburcu edildi. Omurilik yaralanmasına bağlı gelişen OH’nun tedavisinde midodrinin etkili olduğu gözlenmiştir. Bunun yanında, midodrin tedavisinin, OD’nin gelişmesi ya da sıklığının artmasına neden olabileceği akılda tutulmalıdır.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | karataş h, METLİ N, YALÇIN E, AKYÜZ M, İKİZ KAYMAZ T (2018). Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. , 143 - 146. 10.31609/jpmrs.2017-54924 |
| Chicago | karataş hatice gülşah,METLİ Neslihan,YALÇIN ELİF,AKYÜZ Müfit,İKİZ KAYMAZ Tuğba Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. (2018): 143 - 146. 10.31609/jpmrs.2017-54924 |
| MLA | karataş hatice gülşah,METLİ Neslihan,YALÇIN ELİF,AKYÜZ Müfit,İKİZ KAYMAZ Tuğba Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. , 2018, ss.143 - 146. 10.31609/jpmrs.2017-54924 |
| AMA | karataş h,METLİ N,YALÇIN E,AKYÜZ M,İKİZ KAYMAZ T Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. . 2018; 143 - 146. 10.31609/jpmrs.2017-54924 |
| Vancouver | karataş h,METLİ N,YALÇIN E,AKYÜZ M,İKİZ KAYMAZ T Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. . 2018; 143 - 146. 10.31609/jpmrs.2017-54924 |
| IEEE | karataş h,METLİ N,YALÇIN E,AKYÜZ M,İKİZ KAYMAZ T "Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury." , ss.143 - 146, 2018. 10.31609/jpmrs.2017-54924 |
| ISNAD | karataş, hatice gülşah vd. "Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury". (2018), 143-146. https://doi.org/10.31609/jpmrs.2017-54924 |
| APA | karataş h, METLİ N, YALÇIN E, AKYÜZ M, İKİZ KAYMAZ T (2018). Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, 21(3), 143 - 146. 10.31609/jpmrs.2017-54924 |
| Chicago | karataş hatice gülşah,METLİ Neslihan,YALÇIN ELİF,AKYÜZ Müfit,İKİZ KAYMAZ Tuğba Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi 21, no.3 (2018): 143 - 146. 10.31609/jpmrs.2017-54924 |
| MLA | karataş hatice gülşah,METLİ Neslihan,YALÇIN ELİF,AKYÜZ Müfit,İKİZ KAYMAZ Tuğba Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, vol.21, no.3, 2018, ss.143 - 146. 10.31609/jpmrs.2017-54924 |
| AMA | karataş h,METLİ N,YALÇIN E,AKYÜZ M,İKİZ KAYMAZ T Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi. 2018; 21(3): 143 - 146. 10.31609/jpmrs.2017-54924 |
| Vancouver | karataş h,METLİ N,YALÇIN E,AKYÜZ M,İKİZ KAYMAZ T Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury. Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi. 2018; 21(3): 143 - 146. 10.31609/jpmrs.2017-54924 |
| IEEE | karataş h,METLİ N,YALÇIN E,AKYÜZ M,İKİZ KAYMAZ T "Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury." Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi, 21, ss.143 - 146, 2018. 10.31609/jpmrs.2017-54924 |
| ISNAD | karataş, hatice gülşah vd. "Midodrine Treatment in a Patient with Orthostatic Hypotension Associated with Spinal Cord Injury". Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi 21/3 (2018), 143-146. https://doi.org/10.31609/jpmrs.2017-54924 |
