Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity

Sucu, Seyhun; Taysı, Seyithan; BAĞCI, Cahit; KÖMÜRCÜ KARUSERCİ, Özge; ÖRKMEZ, MUSTAFA; Kaplan, Davut Sinan; Celik, Hakim

doi:10.3906/sag-1810-66

Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity

Davut Sinan KAPLAN, (Sakarya Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Sakarya, Türkiye)

Cahit BAĞCI, (Sakarya Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Sakarya, Türkiye)

Mustafa ÖRKMEZ, (Şehitkamil Devlet Hastanesi, Biyokimya Bölümü, Gaziantep, Türkiye)

Özge KÖMÜRCÜ KARUSERCİ, (Gaziantep Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Gaziantep, Türkiye)

Seyhun SUCU, (Cengiz Gökçek Kadın Hastalıkları ve Doğum Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Gaziantep, Türkiye)

Hakim ÇELİK, (Harran Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Şanlıurfa, Türkiye)

Seyithan TAYSI (Gaziantep Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Gaziantep, Türkiye)

Turkish Journal of Medical Sciences

2 0

Yıl: 2019 Cilt: 49 Sayı: 1 Sayfa Aralığı: 87 - 92 Metin Dili: İngilizce DOI: 10.3906/sag-1810-66 İndeks Tarihi: 07-05-2020

Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity

Öz:

Background/aim: The aims of this study were to determine the levels of the total antioxidant status (TAS), the total oxidant status(TOS), the oxidative stress index (OSI), and the concentration of immunoglobulin A (IgA) and M (IgM) in colostrum, and evaluaterelationships between these parameters and maternal age, maternal parity, and infant sex.Materials and methods: The analysis was performed in serum samples of colostrum which were collected from 90 mothers on the firstday of lactation between 10:00 and 12:00 AM.Results: The measurements established that no significant association existed between the TAS level of colostrum and parity, maternalage, or infant sex. However, mothers 18 to 30 years of age had significantly lower colostrum TOS and OSI levels compared withmothers older than 30 years of age. IgA and IgM values of the colostrum of primiparous mothers were significantly higher than those ofmultiparous mothers, whereas no correlations existed with the age of the mother. Additionally, significantly higher colostrum IgA andIgM values were observed in female infants fed colostrum compared with male infants.Conclusion: In conclusion, sex-based hormonal changes in mothers during pregnancy may be associated with the different colostralimmunoglobulin levels for male and female infants.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Szlagatys-Sidorkiewicz A, Zagierski M, Jankowska A, Luczak G, Macur K, Baczek T, Korzon M, Krzykowski G, MartysiakZurowska D, Kaminska B. Longitudinal study of vitamins A, E and lipid oxidative damage in human milk throughout lactation. Early Hum Dev 2012; 88: 421-424.
2. Friel JK, Friesen RW, Harding SV, Roberts LJ. Evidence of oxidative stress in full-term healthy infants. Pediatr Res 2004; 56: 878-882.
3. Riordan J, Wambach K. Breastfeeding and Human Lactation. 4th ed. Sudbury, MA, USA: Jones and Bartlett Publishers; 2010.
4. Castellote C, Casillas R, Ramirez-Santana C, Perez-Cano FJ, Castell M, Moretones MG, Lopez-Sabater MC, Franch A. Premature delivery influences the immunological composition of colostrum and transitional and mature human milk. J Nutr 2011; 141: 1181-1187.
5. Koenig A, de Albuquerque Diniz EM, Barbosa SF, Vaz FA. Immunologic factors in human milk: the effects of gestational age and pasteurization. J Hum Lact 2005; 21: 439-443.
6. Islam SK, Ahmed L, Khan MN, Huque S, Begum A, Yunus AB. Immune components (IgA, IgM, IgG, immune cells) of colostrum of Bangladeshi mothers. Pediatr Int 2006; 48: 543- 548.
7. Striker GA, Casanova LD, Nagao AT. Influence of type of delivery on A, G and M immunoglobulin concentration in maternal colostrum. J Pediatr (Rio J) 2004; 80: 123-128.
8. Ombra MN, Musumeci M, Simpore J, Palano GM, Musumeci S. beta-Endorphin concentration in colostrums of Burkinabe and Sicilian women. Nutrition 2008; 24: 31-36.
9. Erel O. A novel automated method to measure total antioxidant response against potent free radical reactions. Clin Biochem 2004; 37: 112-119.
10. Erel O. A new automated colorimetric method for measuring total oxidant status. Clin Biochem 2005; 38: 1103-1111.
11. Selek S, Aslan M, Horoz M, Gur M, Erel O. Oxidative status and serum PON1 activity in beta-thalassemia minor. Clin Biochem 2007; 40: 287-291.
12. Aycicek A, Erel O, Kocyigit A, Selek S, Demirkol MR. Breast milk provides better antioxidant power than does formula. Nutrition 2006; 22: 616-619.
13. Buescher ES, McIlheran SM. Colostral antioxidants: separation and characterization of two activities in human colostrum. J Pediatr Gastroenterol Nutr 1992; 14: 47-56.
14. Goldman AS, Goldblum RM, Hanson LA. Anti-inflammatory systems in human milk. Adv Exp Med Biol 1990; 262: 69-76.
15. Friel JK, Martin SM, Langdon M, Herzberg GR, Buettner GR. Milk from mothers of both premature and full-term infants provides better antioxidant protection than does infant formula. Pediatr Res 2002; 51: 612-618.
16. L’Abbe MR, Friel JK. Superoxide dismutase and glutathione peroxidase content of human milk from mothers of premature and full-term infants during the first 3 months of lactation. J Pediatr Gastroenterol Nutr 2000; 31: 270-274.
17. Alberti-Fidanza A, Burini G, Perriello G. Total antioxidant capacity of colostrum, and transitional and mature human milk. J Matern Fetal Neonatal Med 2002; 11: 275-279.
18. Zarban A, Taheri F, Chahkandi T, Sharifzadeh G, Khorashadizadeh M. Antioxidant and radical scavenging activity of human colostrum, transitional and mature milk. J Clin Biochem Nutr 2009; 45: 150-154.
19. Sari FN, Akdag A, Dizdar EA, Uras N, Erdeve O, Erel O, Dilmen, U. Antioxidant capacity of fresh and stored breast milk: is −80°C optimal temperature for freeze storage? J Matern Fetal Neonatal Med. 2012; 25: 777-782.
20. Atli M, Aslan M, Emin Kucukoglu M, Temur HB, Taskin A, Celik H. Peripheral lymphocyte DNA damage and oxidative status in football players after a three-day football tournament. Intern Med 2013; 52: 213-217.
21. Baysal E, Taysi S, Aksoy N, Uyar M, Celenk F, Karatas ZA, Tarakcioglu M, Bilinc H, Mumbuc S, Kanlikama M. Serum paraoxonase, arylesterase activity and oxidative status in patients with obstructive sleep apnea syndrome (OSAS). Eur Rev Med Pharmacol Sci 2012; 16: 770-774.
22. Michael JG, Ringenback R, Hottenstein S. The antimicrobial activity of human colostral antibody in the newborn. J Infect Dis 1971; 124: 445-448.
23. Chirico G, Marzollo R, Cortinovis S, Fonte C, Gasparoni A. Antiinfective properties of human milk. J Nutr 2008; 138: 1801S-6S.
24. Newburg DS, Walker WA. Protection of the neonate by the innate immune system of developing gut and of human milk. Pediatr Res 2007; 61: 2-8.
25. Lawrence RA, Lawrence RM. Breastfeeding: A Guide for the Medical Profession. 7th ed. Maryland Heights, MO, USA: Mosby/Elsevier; 2011.
26. Hennart PF, Brasseur DJ, Delogne-Desnoeck JB, Dramaix MM, Robyn CE. Lysozyme, lactoferrin, and secretory immunoglobulin A content in breast milk: influence of duration of lactation, nutrition status, prolactin status, and parity of mother. Am J Clin Nutr 1991; 53: 32-39.
27. Saint L, Smith M, Hartmann PE. The yield and nutrient content of colostrum and milk of women from giving birth to 1 month post-partum. Br J Nutr 1984; 52: 87-95.
28. Hibberd CM, Brooke OG, Carter ND, Haug M, Harzer G. Variation in the composition of breast milk during the first 5 weeks of lactation: implications for the feeding of preterm infants. Arch Dis Child 1982;57:658-662.
29. Prentice A, Prentice AM, Cole TJ, Whitehead RG. Determinants of variations in breast milk protective factor concentrations of rural Gambian mothers. Arch Dis Child 1983; 58: 518-522.
30. Kawano A, Emori Y. Changes in maternal secretory immunoglobulin a levels in human milk during 12 weeks after parturition. Am J Hum Biol 2013; 25: 399-403.
31. Martin RJ, Fanaroff AA, Walsh MC. Fanaroff and Martin’s Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. 9th ed. PA, USA: Saunders/Elsevier; 2015.
32. Bachour P, Yafawi R, Jaber F, Choueiri E, Abdel-Razzak Z. Effects of smoking, mother’s age, body mass index, and parity number on lipid, protein, and secretory immunoglobulin A concentrations of human milk. Breastfeed Med 2012; 7: 179- 188.
33. Lok W, Anteunis LJ, Meesters C, Chenault MN, Haggard MP. Risk factors for failing the hearing screen due to otitis media in Dutch infants. Eur Arch Otorhinolaryngol 2012; 269: 2485- 2496.
34. Venero-Fernandez SJ, Suarez-Medina R, Mora-Faife EC, Garcia-Garcia G, Valle-Infante I, Gomez-Marrero L, AbreuSuarez G, Gonzalez-Valdez J, Fabro-Ortiz DD, FundoraHernandez H et al. Risk factors for wheezing in infants born in Cuba. QJM 2013; 106: 1023-1029.
35. Ahle M, Drott P, Andersson RE. Epidemiology and trends of necrotizing enterocolitis in Sweden: 1987-2009. Pediatrics 2013; 132: e443-51.
36. Moscovis SM, Hall ST, Burns CJ, Scott RJ, Blackwell CC. The male excess in sudden infant deaths. Innate Immun 2013.
37. Kerstjens JM, de Winter AF, Sollie KM, Bocca-Tjeertes IF, Potijk MR, Reijneveld SA, Bos AF. Maternal and pregnancyrelated factors associated with developmental delay in moderately preterm-born children. Obstet Gynecol 2013; 121: 727-733.
38. Herz K, Wohlmuth P, Liedtke B, Schmidt S, Hackeloer BJ, Hellmeyer L. Late preterms: the influence of foetal gender on neonatal outcome. Z Geburtshilfe Neonatol 2012; 216: 141- 146.
39. Baez-Baez GL, Orozco-Valerio Mde J, Davalos-Guzman JC, Mendez-Magana AC, Celis A. Drowning mortality trends in children younger than 5 years old in Mexico, 1979-2008. Rev Invest Clin 2012; 64: 529-534.
40. Zuppa AA, Tornesello A, Papacci P, Tortorolo G, Segni G, Lafuenti G, Moneta E, Diodato A, Sorcini M, Cart S. Relationship between maternal parity, basal prolactin levels and neonatal breast-milk intake. Biology of the Neonate 1988; 53: 144-147.

APA	Kaplan D, BAĞCI C, ÖRKMEZ M, KÖMÜRCÜ KARUSERCİ Ö, Sucu S, Celik H, Taysı S (2019). Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. , 87 - 92. 10.3906/sag-1810-66
Chicago	Kaplan Davut Sinan,BAĞCI Cahit,ÖRKMEZ MUSTAFA,KÖMÜRCÜ KARUSERCİ Özge,Sucu Seyhun,Celik Hakim,Taysı Seyithan Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. (2019): 87 - 92. 10.3906/sag-1810-66
MLA	Kaplan Davut Sinan,BAĞCI Cahit,ÖRKMEZ MUSTAFA,KÖMÜRCÜ KARUSERCİ Özge,Sucu Seyhun,Celik Hakim,Taysı Seyithan Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. , 2019, ss.87 - 92. 10.3906/sag-1810-66
AMA	Kaplan D,BAĞCI C,ÖRKMEZ M,KÖMÜRCÜ KARUSERCİ Ö,Sucu S,Celik H,Taysı S Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. . 2019; 87 - 92. 10.3906/sag-1810-66
Vancouver	Kaplan D,BAĞCI C,ÖRKMEZ M,KÖMÜRCÜ KARUSERCİ Ö,Sucu S,Celik H,Taysı S Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. . 2019; 87 - 92. 10.3906/sag-1810-66
IEEE	Kaplan D,BAĞCI C,ÖRKMEZ M,KÖMÜRCÜ KARUSERCİ Ö,Sucu S,Celik H,Taysı S "Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity." , ss.87 - 92, 2019. 10.3906/sag-1810-66
ISNAD	Kaplan, Davut Sinan vd. "Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity". (2019), 87-92. https://doi.org/10.3906/sag-1810-66

APA	Kaplan D, BAĞCI C, ÖRKMEZ M, KÖMÜRCÜ KARUSERCİ Ö, Sucu S, Celik H, Taysı S (2019). Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. Turkish Journal of Medical Sciences, 49(1), 87 - 92. 10.3906/sag-1810-66
Chicago	Kaplan Davut Sinan,BAĞCI Cahit,ÖRKMEZ MUSTAFA,KÖMÜRCÜ KARUSERCİ Özge,Sucu Seyhun,Celik Hakim,Taysı Seyithan Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. Turkish Journal of Medical Sciences 49, no.1 (2019): 87 - 92. 10.3906/sag-1810-66
MLA	Kaplan Davut Sinan,BAĞCI Cahit,ÖRKMEZ MUSTAFA,KÖMÜRCÜ KARUSERCİ Özge,Sucu Seyhun,Celik Hakim,Taysı Seyithan Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. Turkish Journal of Medical Sciences, vol.49, no.1, 2019, ss.87 - 92. 10.3906/sag-1810-66
AMA	Kaplan D,BAĞCI C,ÖRKMEZ M,KÖMÜRCÜ KARUSERCİ Ö,Sucu S,Celik H,Taysı S Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. Turkish Journal of Medical Sciences. 2019; 49(1): 87 - 92. 10.3906/sag-1810-66
Vancouver	Kaplan D,BAĞCI C,ÖRKMEZ M,KÖMÜRCÜ KARUSERCİ Ö,Sucu S,Celik H,Taysı S Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity. Turkish Journal of Medical Sciences. 2019; 49(1): 87 - 92. 10.3906/sag-1810-66
IEEE	Kaplan D,BAĞCI C,ÖRKMEZ M,KÖMÜRCÜ KARUSERCİ Ö,Sucu S,Celik H,Taysı S "Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity." Turkish Journal of Medical Sciences, 49, ss.87 - 92, 2019. 10.3906/sag-1810-66
ISNAD	Kaplan, Davut Sinan vd. "Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity". Turkish Journal of Medical Sciences 49/1 (2019), 87-92. https://doi.org/10.3906/sag-1810-66