Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

YETER, Hasan H.; Pashayev, Tural; YILDIRIM, Tolga; cetik, sila; Aslan, Abdullah; AKÇAYIR, Ömer; TOPELİ İSKİT, ARZU; EYUPOGLU, NESRIN DAMLA; ARICI, Mustafa

doi:10.3906/sag-1802-183

Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

Hasan H. YETER, (Gazi Üniversitesi)

Tolga YILDIRIM, (Hacettepe Üniversitesi)

Damla EYÜPOĞLU, (Hacettepe Üniversitesi)

Tural PAŞAYEV, (Hacettepe Üniversitesi)

Abdullah ASLAN, (Hacettepe Üniversitesi)

Sıla ÇETİK, (Hacettepe Üniversitesi)

Ömer AKÇAYIR, (Zekai Tahir Burak Hastanesi)

ARZU TOPELİ İSKİT, (Hacettepe Üniversitesi)

Mustafa ARICI (Hacettepe Üniversitesi)

Turkish Journal of Medical Sciences

12 1

Yıl: 2019 Cilt: 49 Sayı: 2 Sayfa Aralığı: 543 - 550 Metin Dili: İngilizce DOI: 10.3906/sag-1802-183 İndeks Tarihi: 10-05-2020

Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients

Öz:

Background/aim: Lack of early predictors of acute kidney injury is currently delaying timely diagnosis. This study was done to evaluatethe relationship between mild to moderate proteinuria and incidence of acute kidney injury (AKI) and 28-day mortality in intensivecare unit (ICU) patients.Material and methods: This observational, retrospective study was conducted in the internal medicine ICU. A total of 796 patients werescreened and 525 patients were used for this analysis. Proteinuria was measured by urine dipstick test. AKI was defined according to theKidney Disease: Improving Global Outcomes (KDIGO) guidelines.Results: Patients with dipstick urine protein positivity on admission had higher proportion of AKI and 28-day mortality compared todipstick urine protein negative group [164 (59.6%) vs. 111 (44.4%) and 101 (36.7%) vs. 54 (21.6%), P = 0.01 and P < 0.01, respectively].Urine dipstick protein positivity was also a significant predictor of 28-day mortality in patients with GFR > 60 mL/min (hazard ratio:1.988, 95% confidence interval 1.380–2.862).Conclusion: Proteinuria before ICU admission is a risk factor for development of AKI within seven days of ICU stay and also is a riskfactor for 28-day mortality, even in patients with GFR > 60 mL/min.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	YETER H, YILDIRIM T, EYUPOGLU N, Pashayev T, Aslan A, cetik s, AKÇAYIR Ö, TOPELİ İSKİT A, ARICI M (2019). Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. , 543 - 550. 10.3906/sag-1802-183
Chicago	YETER Hasan H.,YILDIRIM Tolga,EYUPOGLU NESRIN DAMLA,Pashayev Tural,Aslan Abdullah,cetik sila,AKÇAYIR Ömer,TOPELİ İSKİT ARZU,ARICI Mustafa Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. (2019): 543 - 550. 10.3906/sag-1802-183
MLA	YETER Hasan H.,YILDIRIM Tolga,EYUPOGLU NESRIN DAMLA,Pashayev Tural,Aslan Abdullah,cetik sila,AKÇAYIR Ömer,TOPELİ İSKİT ARZU,ARICI Mustafa Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. , 2019, ss.543 - 550. 10.3906/sag-1802-183
AMA	YETER H,YILDIRIM T,EYUPOGLU N,Pashayev T,Aslan A,cetik s,AKÇAYIR Ö,TOPELİ İSKİT A,ARICI M Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. . 2019; 543 - 550. 10.3906/sag-1802-183
Vancouver	YETER H,YILDIRIM T,EYUPOGLU N,Pashayev T,Aslan A,cetik s,AKÇAYIR Ö,TOPELİ İSKİT A,ARICI M Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. . 2019; 543 - 550. 10.3906/sag-1802-183
IEEE	YETER H,YILDIRIM T,EYUPOGLU N,Pashayev T,Aslan A,cetik s,AKÇAYIR Ö,TOPELİ İSKİT A,ARICI M "Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients." , ss.543 - 550, 2019. 10.3906/sag-1802-183
ISNAD	YETER, Hasan H. vd. "Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients". (2019), 543-550. https://doi.org/10.3906/sag-1802-183

APA	YETER H, YILDIRIM T, EYUPOGLU N, Pashayev T, Aslan A, cetik s, AKÇAYIR Ö, TOPELİ İSKİT A, ARICI M (2019). Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. Turkish Journal of Medical Sciences, 49(2), 543 - 550. 10.3906/sag-1802-183
Chicago	YETER Hasan H.,YILDIRIM Tolga,EYUPOGLU NESRIN DAMLA,Pashayev Tural,Aslan Abdullah,cetik sila,AKÇAYIR Ömer,TOPELİ İSKİT ARZU,ARICI Mustafa Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. Turkish Journal of Medical Sciences 49, no.2 (2019): 543 - 550. 10.3906/sag-1802-183
MLA	YETER Hasan H.,YILDIRIM Tolga,EYUPOGLU NESRIN DAMLA,Pashayev Tural,Aslan Abdullah,cetik sila,AKÇAYIR Ömer,TOPELİ İSKİT ARZU,ARICI Mustafa Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. Turkish Journal of Medical Sciences, vol.49, no.2, 2019, ss.543 - 550. 10.3906/sag-1802-183
AMA	YETER H,YILDIRIM T,EYUPOGLU N,Pashayev T,Aslan A,cetik s,AKÇAYIR Ö,TOPELİ İSKİT A,ARICI M Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. Turkish Journal of Medical Sciences. 2019; 49(2): 543 - 550. 10.3906/sag-1802-183
Vancouver	YETER H,YILDIRIM T,EYUPOGLU N,Pashayev T,Aslan A,cetik s,AKÇAYIR Ö,TOPELİ İSKİT A,ARICI M Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients. Turkish Journal of Medical Sciences. 2019; 49(2): 543 - 550. 10.3906/sag-1802-183
IEEE	YETER H,YILDIRIM T,EYUPOGLU N,Pashayev T,Aslan A,cetik s,AKÇAYIR Ö,TOPELİ İSKİT A,ARICI M "Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients." Turkish Journal of Medical Sciences, 49, ss.543 - 550, 2019. 10.3906/sag-1802-183
ISNAD	YETER, Hasan H. vd. "Mild to moderate proteinuria is a heralding sign for acute kidney injury and mortality for intensive care unit patients". Turkish Journal of Medical Sciences 49/2 (2019), 543-550. https://doi.org/10.3906/sag-1802-183