Yıl: 2019 Cilt: 18 Sayı: 3 Sayfa Aralığı: 214 - 218 Metin Dili: İngilizce İndeks Tarihi: 26-05-2020

EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY

Öz:
Aim: The aim of this study was to evaluate the therapeutic effect of intratympanic steroid injection combined with systemic steroidtreatment in Bell's palsy.Methods: The patients treated for Bell's palsy between December 2016 and January 2019 were divided into two groups including thosetreated with systemic steroid (Group S) and those treated with intratympanic steroid in addition to systemic steroid (Group S+IT). Functional evaluation of the facial nerve was performed with House-Brackmann (H-B) grading system before and at the 6th month after the treatment.Results: There were 21 patients in Group S and 16 patients in Group S+IT. Application H-B grades were 3.7±0.8 (3-5) in Group S and3.8±0.7 (3-5) in Group S+IT, and there was no significant difference between them (p:0.391). Post-treatment 6th month H-B grades were1.3±0.7 (1-4) in Group S and 1.2±0.5 (1-3) in Group S+IT, and there was no significant difference between them (p:0.726). When the groups were evaluated within themselves, significant improvement was observed between pre-treatment and post-treatment 6th month H-B grades (p<0.001).Conclusion: Adjuvant intratympanic steroid injection had no therapeutic effect in Bell's palsy according to functional evaluations at theend of the 6th month.
Anahtar Kelime:

Konular: Kulak, Burun, Boğaz

BELL'S PARALİZİSİNDE İNTRATİMPANİK STEROİD ENJEKSİYONUNUN ETKİNLİĞİ

Öz:
Amaç: Bu çalışmanın amacı, Bell's palsyde sistemik steroid tedavisine kombine edilen intratimpanik steroid enjeksiyonunun tedaviye olan etkisinin değerlendirilmesidir. Yöntemler: 2016 Aralık -2019 Ocak tarihleri arasında Bell's Palsy nedeniyle tedavi edilen hastalar yalnızca sistemik steroid (grup S) ve sistemik steroide ek olarak intratimpanik steroid tedavisi uygulananlar (grup S+IT) olarak iki gruba ayrıldı. Fasyal sinirin fonksiyonel değerlendirmesi tedavi öncesi ve tedaviden sonra 6. ay House-Brackmann (H-B) evreleme sistemi ile yapıldı. Bulgular: Grup S'de 21 ve Grup S+IT'de 16 hasta vardı. Başvuru H-B evreleri grup S'de 3.7±0.8 (3-5) ve grup S+IT'de 3.8±0.7 (3-5) idi ve aralarında anlamlı farklılık yoktu (p:0.391). 6. ay H-B evreleri grup S'de 1.3±0.7 (1-4) ve grup S+IT'de 1.2±0.5 (1-3) idi ve aralarında anlamlı farklılık yoktu (p:0.726). Gruplar kendi içerisinde değerlendirildiğinde ise, tedavi öncesi ve tedavi sonrası 6. ay H-B evreleri arasında belirgin anlamlı iyileşme gözlendi (p<0.001). Sonuç: Bell's palsyde adjuvan intratimpanik steroid enjeksiyonunun 6. ay sonundaki fonksiyonel değerlendirmelere göre tedavi edici etkisi görülmemiştir.
Anahtar Kelime:

Konular: Kulak, Burun, Boğaz
Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
  • 1. Vakharia K, Vakharia K. Bell's Palsy. Facial. Plast. Surg. Clin. North. Am. 2016;24:1-10.
  • 2. Axelsson S, Berg T, Jonsson L, Engström M, Kaverna M, Stjernquist-Desatnik A. Bell's palsy: the effect of prednisolone and/or valaciclovir versus placebo in relation to baseline severity in a randomized controlled trial. Clin. Otolaryngol. 2012;37:283-90.
  • 3. Bryant FL. Intratympanic injection of steroid for treatment of facial paralysis. Laryngoscope. 1973;83:700-6.
  • 4. Chung JH, Park CW, Lee SH, Kim BS, Cho SH, Kim HY, et al. Intratympanic steroid injection for Bell's palsy: preliminary randomized controlled study. Otol. Neurotol. 2014;35:1673-8.
  • 5. House JW, Brackmann DE. Facial nerve grading system. Otolaryngol. Head. Neck. Surg. 1985;93:146-7.
  • 6. Hato N, Matsumoto S, Kisaki H, Takahashi H, Wakisaka H, Honda N, et al. Efficacy of early treatment of Bell's palsy with oral acyclovir and prednisolone. Otol. Neurotol. 2003;24:948-51.
  • 7. Rothendler HH. Bell's palsy treated with cortisone. Am. J. Med. Sci. 1953;225:358-61.
  • 8. Finsterer J. Management of peripheral facial nerve palsy. Eur. Arch. Otorhinolaryngol. 2008;265:743-52.
  • 9. Itoh A, Sakata E. Treatment of vestibular disorders. Acta. Otolaryngol. Suppl. 1991;481:617-23.
  • 10. Silverstein H, Choo D, Rosenberg SI, Kuhn J, Seidman M, Stein I. Intratympanic steroid treatment of inner ear disease and tinnitus (preliminary report). Ear Nose Throat J. 1996;75:468-71, 474, 476 passim.
  • 11. DiMartino E, Sellhaus B, Haensel J, Schlegel JG, Westhofen M, Prescher A. Fallopian canal dehiscences: a survey of clinical and anatomical findings. Eur. Arch. Otorhinolaryngol. 2005;262:120-6.
  • 12. Takahashi H, Sando I. Facial canal dehiscence: histologic study and computer reconstruction. Ann. Otol. Rhinol. Laryngol. 1992;101: 925-30.
  • 13. Baxter A. Dehiscence of the Fallopian canal. An anatomical study. J. Laryngol. Otol. 1971;85:587-94.
  • 14. Berg T, Bylund N, Marsk E, Jonsson L, Kanerva M, Hultcrantz M, et al. The effect of prednisolone on sequelae in Bell's palsy. Arch. Otolaryngol. Head. Neck. Surg. 2012; 138: 445-9.
  • 15. Kang HM, Jung SY, Byun JY, Park MS, Yeo SG. Steroid plus antiviral treatment for Bell's palsy. J. Intern. Med. 2015;277:532-9.
APA Demir E, ÇELİKER M, UFUK KILIÇTAŞ A, ÇELEBİ ERDİVANLI Ö, TERZİ S, COŞKUN Z, DURSUN E (2019). EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. , 214 - 218.
Chicago Demir Emine,ÇELİKER METİN,UFUK KILIÇTAŞ Ahmet,ÇELEBİ ERDİVANLI ÖZLEM,TERZİ Suat,COŞKUN Zerrin Özergin,DURSUN Engin EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. (2019): 214 - 218.
MLA Demir Emine,ÇELİKER METİN,UFUK KILIÇTAŞ Ahmet,ÇELEBİ ERDİVANLI ÖZLEM,TERZİ Suat,COŞKUN Zerrin Özergin,DURSUN Engin EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. , 2019, ss.214 - 218.
AMA Demir E,ÇELİKER M,UFUK KILIÇTAŞ A,ÇELEBİ ERDİVANLI Ö,TERZİ S,COŞKUN Z,DURSUN E EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. . 2019; 214 - 218.
Vancouver Demir E,ÇELİKER M,UFUK KILIÇTAŞ A,ÇELEBİ ERDİVANLI Ö,TERZİ S,COŞKUN Z,DURSUN E EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. . 2019; 214 - 218.
IEEE Demir E,ÇELİKER M,UFUK KILIÇTAŞ A,ÇELEBİ ERDİVANLI Ö,TERZİ S,COŞKUN Z,DURSUN E "EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY." , ss.214 - 218, 2019.
ISNAD Demir, Emine vd. "EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY". (2019), 214-218.
APA Demir E, ÇELİKER M, UFUK KILIÇTAŞ A, ÇELEBİ ERDİVANLI Ö, TERZİ S, COŞKUN Z, DURSUN E (2019). EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. KBB-Forum, 18(3), 214 - 218.
Chicago Demir Emine,ÇELİKER METİN,UFUK KILIÇTAŞ Ahmet,ÇELEBİ ERDİVANLI ÖZLEM,TERZİ Suat,COŞKUN Zerrin Özergin,DURSUN Engin EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. KBB-Forum 18, no.3 (2019): 214 - 218.
MLA Demir Emine,ÇELİKER METİN,UFUK KILIÇTAŞ Ahmet,ÇELEBİ ERDİVANLI ÖZLEM,TERZİ Suat,COŞKUN Zerrin Özergin,DURSUN Engin EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. KBB-Forum, vol.18, no.3, 2019, ss.214 - 218.
AMA Demir E,ÇELİKER M,UFUK KILIÇTAŞ A,ÇELEBİ ERDİVANLI Ö,TERZİ S,COŞKUN Z,DURSUN E EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. KBB-Forum. 2019; 18(3): 214 - 218.
Vancouver Demir E,ÇELİKER M,UFUK KILIÇTAŞ A,ÇELEBİ ERDİVANLI Ö,TERZİ S,COŞKUN Z,DURSUN E EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY. KBB-Forum. 2019; 18(3): 214 - 218.
IEEE Demir E,ÇELİKER M,UFUK KILIÇTAŞ A,ÇELEBİ ERDİVANLI Ö,TERZİ S,COŞKUN Z,DURSUN E "EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY." KBB-Forum, 18, ss.214 - 218, 2019.
ISNAD Demir, Emine vd. "EFFICACY OF INTRATYMPANIC STEROID INJECTION IN BELL'S PALSY". KBB-Forum 18/3 (2019), 214-218.