Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?

TASLAMACIOĞLU DUMAN, TUBA; ATAK TEL, Burçin Meryem

Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?

Tuba TASLAMACIOĞLU DUMAN, (Bolu Abant İzzet Baysal Üniversitesi)

Burçin Meryem ATAK TEL (Bolu Abant İzzet Baysal Üniversitesi)

Kocaeli Tıp Dergisi

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Yıl: 2019 Cilt: 8 Sayı: 3 Sayfa Aralığı: 50 - 54 Metin Dili: İngilizce İndeks Tarihi: 29-05-2020

Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?

Öz:

INTRODUCTION: Hemogram parameters are considered as inflammatory markers in various diseases. The objective of this study was to assess mean platelet volume to lymphocyte ratio (MPVLR) of subjects with IBS and to compare to those in healthy population.METHODS: Patients with IBS whose admissions to our outpatient internal medicine clinic were enrolled to the study. Patients with IBS were divided into two groups according to the predominant symptom, either IBS diarrhea predominant (IBS-D) or IBS constipation predominant (IBS-C). Healthy volunteers were enrolled as control group. General characteristics and MPVLR levels of the groups compared.RESULTS: The MPVLR of IBS-C, IBS-D and control groups were 0.005 (0.001), 0.004 (0.001) and 0.003 (0.001), respectively (p<0.001). Post Hoc test revealed that MPVLR of IBS-C and IBS-D groups were similar (p=0.44) and MPVLR of control groups was significantly lower than that of the IBS-C (p<0.001) and IBS-D (p<0.001) groups.DISCUSSION and CONCLUSION: The main outcome of present study was that MPVLR could be used as a marker of IBS. However, it is not useful in differentiating IBS constipation predominance from IBS diarrhea predominance. In conclusion, despite increased MPVLR could not differentiate IBS constipation predominance from the IBS diarrheapredominance, it could be useful in establishing the diagnosis of IBS.

Anahtar Kelime:

Ortalama Trombosit Hacmi/Lenfosit Sayısı Oranı İrritabl Barsak Sebdromu ve Subtibleri ile İlişkili midir ?

Öz:

GİRİŞ ve AMAÇ: Hemogram parametreleri birçok çalışmada inflamatuvar belirteç olarak kullanılmaktadır. Bu çalışmamızdaki amacımız İBS ve sağlıklı kontrollerdeki ortalama trombosit hacmi/lenfosit oranının (MPVLR) karşılaştırılmasıdır. YÖNTEM ve GEREÇLER: İç hastalıkları polikliniğimize başvuran İBS’li hastalar çalışmamıza alındı. İBS’li hastalar diyare predominat İBS (IBS-D) ve konstipasyon predominant İBS (IBS-C) olarak iki ana gruba ayrıldı. Sağlıklı kişilerden de kontrol grubu oluşturuldu. Çalışmamızda grupların genel özellikleri ve MPVLR seviyeleri karşılaştırıldı. BULGULAR: IBS-C, IBS-D ve kontrol gruplardaki MPVLR sırasıyla; 0.005 (0.001), 0.004 (0.001) ve 0.003 (0.001), (p<0.001) idi. Post Hoc testi ile IBS-C ve IBS-D gruplarındaki MPVLR oranları benzer olup (p=0.44), MPVLR control grupta ise IBS-C (p<0.001) ve IBS-D (p<0.001) gruplarından anlamlı olarak düşük saptandı. TARTIŞMA ve SONUÇ: MPVLR, İBS hastalarında inflamatuvar marker olarak kullanılabileceği bu çalışmamızdaki ana sonucumuzdur. Ancak İBS grupları arasında anlamlı fark saptanmamıştır. Sonuçta İBS-C ve İBS-D arasında MPVLR benzer olmakla birlikte İBS hastalarının sağlıklılardan ayrımında kullanılabilir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	TASLAMACIOĞLU DUMAN T, ATAK TEL B (2019). Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. , 50 - 54.
Chicago	TASLAMACIOĞLU DUMAN TUBA,ATAK TEL Burçin Meryem Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. (2019): 50 - 54.
MLA	TASLAMACIOĞLU DUMAN TUBA,ATAK TEL Burçin Meryem Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. , 2019, ss.50 - 54.
AMA	TASLAMACIOĞLU DUMAN T,ATAK TEL B Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. . 2019; 50 - 54.
Vancouver	TASLAMACIOĞLU DUMAN T,ATAK TEL B Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. . 2019; 50 - 54.
IEEE	TASLAMACIOĞLU DUMAN T,ATAK TEL B "Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?." , ss.50 - 54, 2019.
ISNAD	TASLAMACIOĞLU DUMAN, TUBA - ATAK TEL, Burçin Meryem. "Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?". (2019), 50-54.

APA	TASLAMACIOĞLU DUMAN T, ATAK TEL B (2019). Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. Kocaeli Tıp Dergisi, 8(3), 50 - 54.
Chicago	TASLAMACIOĞLU DUMAN TUBA,ATAK TEL Burçin Meryem Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. Kocaeli Tıp Dergisi 8, no.3 (2019): 50 - 54.
MLA	TASLAMACIOĞLU DUMAN TUBA,ATAK TEL Burçin Meryem Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. Kocaeli Tıp Dergisi, vol.8, no.3, 2019, ss.50 - 54.
AMA	TASLAMACIOĞLU DUMAN T,ATAK TEL B Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. Kocaeli Tıp Dergisi. 2019; 8(3): 50 - 54.
Vancouver	TASLAMACIOĞLU DUMAN T,ATAK TEL B Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. Kocaeli Tıp Dergisi. 2019; 8(3): 50 - 54.
IEEE	TASLAMACIOĞLU DUMAN T,ATAK TEL B "Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?." Kocaeli Tıp Dergisi, 8, ss.50 - 54, 2019.
ISNAD	TASLAMACIOĞLU DUMAN, TUBA - ATAK TEL, Burçin Meryem. "Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?". Kocaeli Tıp Dergisi 8/3 (2019), 50-54.