Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease
Yıl: 2016 Cilt: 23 Sayı: 1 Sayfa Aralığı: 62 - 69 Metin Dili: İngilizce DOI: 10.5455/jtomc.2015.3224 İndeks Tarihi: 03-06-2020
Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease
Öz: Objective: In a unilateral onset Idiopathic Parkinson disease, sympathetic skin responseselicited from previously and markedly affected and also from unaffected palm andforehead were recorded before and after the treatment. The difference (if any) insympathetic skin responses recordings obtained from patients and control cases and theimpact of Idiopathic Parkinson disease treatments on response sympathetic skinresponses were investigated.Materials and Methods: A total of 23 patients and 22 healthy volunteers were includedin the study. The patients were examined for autonomic nervous system involvementand the patients with facial hyperhidrosis were determined. Sympathetic skin responsesof the patients were recorded twice (before and after initiation of therapy) from bothsides of the forehead and both hands and compared with healthy volunteers.Results: A statistically significant difference was not detected between sympathetic skinresponses amplitudes of left and right hands in Tests 1 and 2. Significantly lowersympathetic skin responses amplitudes were observed in Test 2. Correlations amongamplitudes of hand sympathetic skin responses, Hoehn and Yahr Staging and UnifiedParkinson’s Disease Rating Scale scores demonstrated significant decreases inamplitudes of sympathetic skin responses in parallel with disease progression. Left sidedominancy in patients with hyperhidrosis is statistically significant.Conclusion: Detection of lower amplitudes in hand sympathetic skin responses aftertherapy may be due to habituation or used drugs. Significant decreases in amplitudes ofsympathetic skin responses in parallel with disease progression were observed. No dataconcerning left side dominancy in the patient group with hyperhidrosis have beendetected so far.
Anahtar Kelime: İdyopatik Parkinson Hastalığı’nda Frontal Bölgeden Kaydedilen Sempatik Deri Yanıtlarının Tutulum Tarafına Göre Etkilenimi
Öz: Amaç: Bu çalışmada, unilateral başlangıçlı İdyopatik Parkinson Hastalığı’nda, daha fazla tutulan tarafta sempatik deri yanıtlarında diğer tarafa göre fark olup olmadığı ve sempatik deri yanıtları üzerinde kullanılan tedavilerin etkisi araştırılmış ve sağlıklı gönüllüler ile karşılaştırılmıştır. Gereç ve Yöntemler: Çalışmaya 23 hasta ve 22 sağlıklı gönüllü alınmıştır. Hastalar otonom sinir sistemi bulguları ve yüzde hiperhidrozis varlığı açısından sorgulanmıştır. Tedavi öncesi (test 1) ve tedavi sonrası (test 2) sempatik deri yanıtları iki yanlı frontal ve el bölgesinden kayıtlanarak kontrol grubuyla karşılaştırılmıştır. Bulgular: El yanıtlarında Test 1, Test 2 ve kontrol grubunda sağ ve sol taraf arasında, aynı zamanda hasta-sağlam taraf arasında istatistiksel olarak anlamlı bir farklılık göstermemiştir. İlaç tedavisi sonrasında yanıt amplitüdlerinin istatistiksel olarak anlamlı olarak düştüğü kaydedilmiştir. El yanıt amplitüdleri ile Hoehn and Yahr Staging (H&Y) skorları ve Unified Parkinson’s Disease Rating Scale (UPDRS) puanları arasında hastalık ilerledikçe negatif korelasyon gözlenmiştir. Sol taraf başlangıçlı olan hastalarda hiperhidroz varlığı sağ taraf başlangıç olanlara göre istatistiksel olarak anlamlı bulunmuştur. Sonuç: Tedavi sonrasında tedavi öncesine göre el yanıtlarında amplitüdlerin düşmesi, habituasyona veya kullanılan ilaçlara bağlı olabileceği düşünülmüştür. Hastalık ilerledikçe amplitüdlerinin istatistiksel olarak anlamlı düştüğü gözlenmiştir. Hiperhidrozlu grupta sol taraf başlangıçlı hastalık olma olasılığının yüksek olması ile ilgili bu güne kadar literatürde herhangi bir bilgiye rastlanmamıştır. Bu konuda daha kapsamlı çalışmalara ihtiyaç vardır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | AYDIN TURKOGLU Ş, YILDIZ S, YILDIZ N, BOLAC E (2016). Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. , 62 - 69. 10.5455/jtomc.2015.3224 |
| Chicago | AYDIN TURKOGLU Şule,YILDIZ Serpil,YILDIZ Nebil,BOLAC Elif Sultan Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. (2016): 62 - 69. 10.5455/jtomc.2015.3224 |
| MLA | AYDIN TURKOGLU Şule,YILDIZ Serpil,YILDIZ Nebil,BOLAC Elif Sultan Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. , 2016, ss.62 - 69. 10.5455/jtomc.2015.3224 |
| AMA | AYDIN TURKOGLU Ş,YILDIZ S,YILDIZ N,BOLAC E Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. . 2016; 62 - 69. 10.5455/jtomc.2015.3224 |
| Vancouver | AYDIN TURKOGLU Ş,YILDIZ S,YILDIZ N,BOLAC E Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. . 2016; 62 - 69. 10.5455/jtomc.2015.3224 |
| IEEE | AYDIN TURKOGLU Ş,YILDIZ S,YILDIZ N,BOLAC E "Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease." , ss.62 - 69, 2016. 10.5455/jtomc.2015.3224 |
| ISNAD | AYDIN TURKOGLU, Şule vd. "Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease". (2016), 62-69. https://doi.org/10.5455/jtomc.2015.3224 |
| APA | AYDIN TURKOGLU Ş, YILDIZ S, YILDIZ N, BOLAC E (2016). Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 23(1), 62 - 69. 10.5455/jtomc.2015.3224 |
| Chicago | AYDIN TURKOGLU Şule,YILDIZ Serpil,YILDIZ Nebil,BOLAC Elif Sultan Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 23, no.1 (2016): 62 - 69. 10.5455/jtomc.2015.3224 |
| MLA | AYDIN TURKOGLU Şule,YILDIZ Serpil,YILDIZ Nebil,BOLAC Elif Sultan Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, vol.23, no.1, 2016, ss.62 - 69. 10.5455/jtomc.2015.3224 |
| AMA | AYDIN TURKOGLU Ş,YILDIZ S,YILDIZ N,BOLAC E Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2016; 23(1): 62 - 69. 10.5455/jtomc.2015.3224 |
| Vancouver | AYDIN TURKOGLU Ş,YILDIZ S,YILDIZ N,BOLAC E Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2016; 23(1): 62 - 69. 10.5455/jtomc.2015.3224 |
| IEEE | AYDIN TURKOGLU Ş,YILDIZ S,YILDIZ N,BOLAC E "Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease." İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 23, ss.62 - 69, 2016. 10.5455/jtomc.2015.3224 |
| ISNAD | AYDIN TURKOGLU, Şule vd. "Side-based Activation of Sympathetic Skin Responses Recorded from the Frontal Region in Idiopathic Parkinson's Disease". İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 23/1 (2016), 62-69. https://doi.org/10.5455/jtomc.2015.3224 |
