Yıl: 2019 Cilt: 21 Sayı: 3 Sayfa Aralığı: 182 - 186 Metin Dili: İngilizce DOI: 10.4103/ejop.ejop_80_18 İndeks Tarihi: 30-03-2020

Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study

Öz:
BACKGROUND AND AIM: Red blood cell distribution width (RDW) elevation occurs in variousinflammatory/infectious conditions. RDW levels during monitoring have not been investigatedprospectively in community‑acquired pneumonia (CAP). In CAP, the relationship betweenantibiotherapy response and RDW levels is unclear.MATERIALS AND METHODS: This prospective cohort study included a total of 65 CAP patients.Total complete blood cell (including RDW) count, blood biochemistry analysis, and arterial blood gastests were performed on admission. RDW was also performed on the 7th day.RESULTS: Total mean RDW level was 16.2% ± 1.9% in the study population. The level was17.7% ± 2.1% in nonsurviving CAP patients and 15.9% ± 1.8% in surviving CAP patients (P = 0.01).Pretreatment RDW levels were 16.2% ± 1.9% as compared to 15.3% ± 2.2% on the 7th day (P = 0.002).An RDW cutoff >16.5% predicted 30‑day mortality with 78% sensitivity and 70% specificity. The riskof 30‑day mortality was 9‑fold higher in patients with elevated RDW as assessed by multivariatelogistic regression analysis for CAP.CONCLUSION: RDW can be used as an important parameter in assessing response to antibiotherapy.We also speculate that high RDW is a poor prognostic marker for CAP.
Anahtar Kelime:

Konular: Solunum Sistemi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ÇINARKA H, GÜMÜŞ A, ÖZYURT S, Karataş M, GIAKOUP D, CÜRE M, KAYHAN S, DOĞAN D, ŞAHİN Ü (2019). Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. , 182 - 186. 10.4103/ejop.ejop_80_18
Chicago ÇINARKA Halit,GÜMÜŞ Aziz,ÖZYURT SONGÜL,Karataş Mevlüt,GIAKOUP Derya,CÜRE Medine Cumhur,KAYHAN Servet,DOĞAN Deniz,ŞAHİN Ünal Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. (2019): 182 - 186. 10.4103/ejop.ejop_80_18
MLA ÇINARKA Halit,GÜMÜŞ Aziz,ÖZYURT SONGÜL,Karataş Mevlüt,GIAKOUP Derya,CÜRE Medine Cumhur,KAYHAN Servet,DOĞAN Deniz,ŞAHİN Ünal Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. , 2019, ss.182 - 186. 10.4103/ejop.ejop_80_18
AMA ÇINARKA H,GÜMÜŞ A,ÖZYURT S,Karataş M,GIAKOUP D,CÜRE M,KAYHAN S,DOĞAN D,ŞAHİN Ü Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. . 2019; 182 - 186. 10.4103/ejop.ejop_80_18
Vancouver ÇINARKA H,GÜMÜŞ A,ÖZYURT S,Karataş M,GIAKOUP D,CÜRE M,KAYHAN S,DOĞAN D,ŞAHİN Ü Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. . 2019; 182 - 186. 10.4103/ejop.ejop_80_18
IEEE ÇINARKA H,GÜMÜŞ A,ÖZYURT S,Karataş M,GIAKOUP D,CÜRE M,KAYHAN S,DOĞAN D,ŞAHİN Ü "Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study." , ss.182 - 186, 2019. 10.4103/ejop.ejop_80_18
ISNAD ÇINARKA, Halit vd. "Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study". (2019), 182-186. https://doi.org/10.4103/ejop.ejop_80_18
APA ÇINARKA H, GÜMÜŞ A, ÖZYURT S, Karataş M, GIAKOUP D, CÜRE M, KAYHAN S, DOĞAN D, ŞAHİN Ü (2019). Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. Eurasian Journal of Pulmonology, 21(3), 182 - 186. 10.4103/ejop.ejop_80_18
Chicago ÇINARKA Halit,GÜMÜŞ Aziz,ÖZYURT SONGÜL,Karataş Mevlüt,GIAKOUP Derya,CÜRE Medine Cumhur,KAYHAN Servet,DOĞAN Deniz,ŞAHİN Ünal Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. Eurasian Journal of Pulmonology 21, no.3 (2019): 182 - 186. 10.4103/ejop.ejop_80_18
MLA ÇINARKA Halit,GÜMÜŞ Aziz,ÖZYURT SONGÜL,Karataş Mevlüt,GIAKOUP Derya,CÜRE Medine Cumhur,KAYHAN Servet,DOĞAN Deniz,ŞAHİN Ünal Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. Eurasian Journal of Pulmonology, vol.21, no.3, 2019, ss.182 - 186. 10.4103/ejop.ejop_80_18
AMA ÇINARKA H,GÜMÜŞ A,ÖZYURT S,Karataş M,GIAKOUP D,CÜRE M,KAYHAN S,DOĞAN D,ŞAHİN Ü Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. Eurasian Journal of Pulmonology. 2019; 21(3): 182 - 186. 10.4103/ejop.ejop_80_18
Vancouver ÇINARKA H,GÜMÜŞ A,ÖZYURT S,Karataş M,GIAKOUP D,CÜRE M,KAYHAN S,DOĞAN D,ŞAHİN Ü Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study. Eurasian Journal of Pulmonology. 2019; 21(3): 182 - 186. 10.4103/ejop.ejop_80_18
IEEE ÇINARKA H,GÜMÜŞ A,ÖZYURT S,Karataş M,GIAKOUP D,CÜRE M,KAYHAN S,DOĞAN D,ŞAHİN Ü "Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study." Eurasian Journal of Pulmonology, 21, ss.182 - 186, 2019. 10.4103/ejop.ejop_80_18
ISNAD ÇINARKA, Halit vd. "Role of red cell distribution width in assessing response to treatment and prognosis in community‑acquired pneumonia: A prospective study". Eurasian Journal of Pulmonology 21/3 (2019), 182-186. https://doi.org/10.4103/ejop.ejop_80_18