Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices

Yıl: 2019 Cilt: 9 Sayı: 3 Sayfa Aralığı: 138 - 144 Metin Dili: İngilizce DOI: 10.5577/intdentres.2019.vol9.no3.8 İndeks Tarihi: 01-04-2020

Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices

Öz:
Aim: The goal of this particular research was to scrutinize theremineralization effects of fluoride varnish, casein phosphopeptideamorphous calcium phosphates (CPP-ACP) and casein phosphopeptideamorphous calcium fluoride phosphates (CPP-ACFP) cream, andtricalcium phosphate (TCP) varnish.Methodology: The study was designed as an experimental researchwhereby samples with early artificial caries lesions were randomlydivided into the following 5 groups with 20 samples in each group: (I)control, (II) fluoride varnish, (III) CPP-ACP cream, (IV) CPP-ACFP creamand (V) TCP varnish. The effectiveness of these remineralization agentswas evaluated using a laser fluorescence device (DIAGNOdent), a scanningelectron microscope (SEM) and energy dispersive X-ray analysis (EDX).Results: In the pre- and post-treatment evaluations, the DIAGNOdentremineralization measurements were statistically significant in all thegroups, except the control group (p < 0.05). In comparison with theDIAGNOdent measurements, the CPP-ACFP group was found to havesignificantly higher remineralization than the fluoride group (p < 0.05),while no significant differences were found between the other groups (p> 0.05). The EDX analysis evaluated the Ca/P ratio between the groups.These results indicated that the CPP-ACFP group was significantly higherthan the control group, the CPP-ACP group and the TCP group (p < 0.05);no significant differences were found between the CPP-ACFP group andthe fluoride group (p > 0.05). In SEM imaging, the most extensive mineralaccumulation was observed in the CPP-ACFP group.Conclusions: Three analytical methods demonstrated that CPP-ACFPwas the most effective remineralization material tested in this study.
Anahtar Kelime:

Konular: Diş Hekimliği
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Clarkson JJ, McLoughlin J. Role of fluoride in oral health promotion. Int Dent J. 2000;50(3):119–28. (Crossref)
  • 2. Keskin G. Kazein Fosfopeptit Amorf Kalsiyum Fosfat Ve Amelogeninin Mine Remineralizasyonuna Etkisi. İnönü Üniversitesi; 2014.
  • 3. Çetin B, Avşar A, Ulusoy AT. Kazein içerikli besinler ve dental ürünler. Atatürk Üniversitesi Diş Hekim Fakültesi Derg. 2011;(4):24–31.
  • 4. Rechmann P, Bekmezian S, Rechmann BM, Chaffee BW, Featherstone JD. MI Varnish and MI Paste Plus in a caries prevention and remineralization study : a randomized controlled trial. Clin Oral Investig. 2018;22(6):2229–2239. (Crossref)
  • 5. Reynolds EC. Anticariogenic complexes of amorphous calcium phosphate stabilized by casein phosphopeptides: A review. Spec Care Dent. 1998;18(1):8–16. (Crossref)
  • 6. Karlinsey RL, Mackey AC, Walker ER, Frederick KE. Preparation, characterization and in vitro efficacy of an acid-modified β- TCP material for dental hard-tissue remineralization. Acta Biomater. 2010;6(3):969–78. (Crossref)
  • 7. Hegde MN, Moany A. Remineralization of enamel subsurface lesions with casein phosphopeptide-amorphous calcium phosphate: A quantitative energy dispersive X-ray analysis using scanning electron microscopy: An in vitro study. J Conserv Dent. 2012;15(1):61–7.
  • 8. Dilber E, Malkoc MA, Ozturk AN, Ozturk F. Effect of various laser irradiations on the mineral content of dentin. Eur J Dent. 2013;7(1):74–80.
  • 9. Memiş HB. Teobromin, mine matriks protein türevi, kazein fosfopeptit amorf kalsiyum fosfat ve deniz tuzunun ortodontik braketler etrafındaki minenin remineralizasyonuna etkisinin in vitro olarak incelenmesi. 2018.
  • 10. Pai D, Bhat S, Taranath A, Sargod S, Pai V. Use of Laser fluorescence and Scanning Electron Microscope to Evaluate Remineralization of Incipient Enamel Lesions Remineralized by Topical Application of Casein Phospho Peptide Amorphous Calcium Phosphate (CPP-ACP) Containing Cream. J Clin Pediatr Dent. 2008;32(3):201–6. (Crossref)
  • 11. Jayarajan J, Janardhanam P, Jayakumar P, Deepika. Efficacy of CPP-ACP and CPP-ACPF on enamel remineralization - an in vitro study using scanning electron microscope and DIAGNOdent. Indian J Dent Res. 2011;22(1):77–82. (Crossref)
  • 12. Bhat S, Hegde K, Habibullah M, Bernhardt V. Incipient Enamel Lesions Remineralization using Casein Phosphopeptide Amorphous Calcium Phosphate Cream with and without Fluoride: A Laser Fluorescence Study. J Clin Pediatr Dent. 2012;36(4):253–355. (Crossref)
  • 13. Patil N, Choudhari S, Kulkarni S, Joshi SR. Comparative evaluation of remineralizing potential of three agents on artificially demineralized human enamel: An in vitro study. J Conserv Dent. 2013;16(2):116–20. (Crossref)
  • 14. Allama Prabhu, BG, Sakeenabhi B, Prashanth GM, Subramaniam R, Ragher M. Effect of fluoride varnish and dentifrices and its combination on deciduous enamel demineralization: An In vitro study. J Pharm Bioallied Sci. 2017;9(1):112–6. (Crossref)
  • 15. Shetty S, Hegde M, Bopanna T. Enamel remineralization assessment after treatment with three different remineralizing agents using surface microhardness: An in vitro study. J Conserv Dent. 2014;17(1):49. (Crossref)
  • 16. Zhou C, Zhang D, Bai Y, Li S. Casein phosphopeptide–amorphous calcium phosphate remineralization of primary teeth early enamel lesions. J Dent. 2014;42(1):21–9. (Crossref)
  • 17. ten Cate JM, Duijsters PPE. Alternating Demineralization and Remineralization of Artificial Enamel Lesions. Caries Res. 1982;16(3):201–10. (Crossref)
  • 18. Kamath P, Nayak R, Kamath SU, Pai D. A comparative evaluation of the remineralization potential of three commercially available remineralizing agents on white spot lesions in primary teeth: An in vitro study. J Indian Soc Pedod Prev Dent [Internet]. 2017 [cited 2018 Sep 20];35(3):229–37. (Crossref)
APA TATAR E, TOPTANCI I (2019). Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. , 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
Chicago TATAR Emine,TOPTANCI ISMET REZANI Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. (2019): 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
MLA TATAR Emine,TOPTANCI ISMET REZANI Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. , 2019, ss.138 - 144. 10.5577/intdentres.2019.vol9.no3.8
AMA TATAR E,TOPTANCI I Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. . 2019; 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
Vancouver TATAR E,TOPTANCI I Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. . 2019; 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
IEEE TATAR E,TOPTANCI I "Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices." , ss.138 - 144, 2019. 10.5577/intdentres.2019.vol9.no3.8
ISNAD TATAR, Emine - TOPTANCI, ISMET REZANI. "Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices". (2019), 138-144. https://doi.org/10.5577/intdentres.2019.vol9.no3.8
APA TATAR E, TOPTANCI I (2019). Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. International Dental Research, 9(3), 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
Chicago TATAR Emine,TOPTANCI ISMET REZANI Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. International Dental Research 9, no.3 (2019): 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
MLA TATAR Emine,TOPTANCI ISMET REZANI Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. International Dental Research, vol.9, no.3, 2019, ss.138 - 144. 10.5577/intdentres.2019.vol9.no3.8
AMA TATAR E,TOPTANCI I Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. International Dental Research. 2019; 9(3): 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
Vancouver TATAR E,TOPTANCI I Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices. International Dental Research. 2019; 9(3): 138 - 144. 10.5577/intdentres.2019.vol9.no3.8
IEEE TATAR E,TOPTANCI I "Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices." International Dental Research, 9, ss.138 - 144, 2019. 10.5577/intdentres.2019.vol9.no3.8
ISNAD TATAR, Emine - TOPTANCI, ISMET REZANI. "Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices". International Dental Research 9/3 (2019), 138-144. https://doi.org/10.5577/intdentres.2019.vol9.no3.8