Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province

SAHIN, MUSTAFA; kayadibi, huseyin; karabulut, alpaslan

Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province

Mustafa ŞAHİN, (Hitit Üniversitesi)

Alpaslan KARABULUT, (Hitit Üniversitesi)

Hüseyin KAYADİBİ (Hitit Üniversitesi)

International Journal of Medical Biochemistry

3 0

Yıl: 2019 Cilt: 2 Sayı: 2 Sayfa Aralığı: 60 - 64 Metin Dili: İngilizce İndeks Tarihi: 08-04-2020

Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province

Öz:

Objectives: The aim of this study was to identify and analyze the incidence of thyroid dysfunction in geriatric patientsin Corum province, Turkey.Methods: The results of thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) tests,as well as the demographic characteristics of 220 randomized patients were retrospectively investigated. Patients whohad a total or partial thyroidectomy surgery and those receiving any medical thyroid treatment were not included inthe study. The patients were divided into 5 groups: subclinical hypothyroidism, hypothyroidism, euthyroid, subclinicalhyperthyroidism, and hyperthyroidism.Results: In the group, 114 were male and 106 were female. The mean age of the male and female patients was 74±7years and 75±7 years, respectively. The entire study group had a median TSH of 0.94 μIU/mL (25th-75th percentile, interquartilerange [IQR] 0.33-1.86 μIU/mL), a median FT4 of 1.14 ng/dL (IQR: 1.02-1.33 ng/dL), and a median FT3 of 2.73pg/mL (IQR: 2.25-3.11 pg/mL). For male patients, the median TSH was 0.87 μIU/mL (IQR: 0.36-1.66 μIU/mL), the medianFT4 was 1.14 ng/dL (IQR: 1.02-1.29 ng/dL), and the median FT3 was 2.74 pg/mL (IQR: 2.18-3.15 pg/mL), while for femalepatients the median TSH was 0.95 μIU/mL (IQR: 0.20-2.21 μIU/mL), the median FT4 was 1.17 ng/dL (IQR: 1.06-1.38 ng/dL), and the median FT3 was 2.72 pg/mL (2.31-3.10 pg/mL). Of the males, 1.8% had subclinical hypothyroidism, another1.8% had hypothyroidism, 72.8% were euthyroid, 19.3% had subclinical hyperthyroidism, and 4.4% had hyperthyroidism.Among the females, there were findings of 2.8% subclinical hypothyroidism, 1.9% hypothyroidism, 64.2%euthyroid, 26.4% subclinical hyperthyroidism, and 4.7% hyperthyroidism. No statistically significant difference was observedwhen the diagnosis incidence was compared according to gender (p=0.696).Conclusion: Independent of gender, the geriatric patient population had a high incidence of subclinical hyperthyroidism,which often has a delayed diagnosis. This can complicate the prompt diagnosis of other metabolic diseases.As thyroid function affects the metabolism of the entire body, thyroid hormone status should be investigated whenconsidering other metabolic diseases in geriatric patients. Excluding thyroid disfunction could save time in makingan accurate diagnosis and providing treatment. Furthermore, since thyroid diseases are influenced by environmentaliodine, regional thyroid disease incidence studies should be performed.

Anahtar Kelime:

Konular: Biyoteknoloji ve Uygulamalı Mikrobiyoloji Biyokimya ve Moleküler Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SAHIN M, karabulut a, kayadibi h (2019). Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. , 60 - 64.
Chicago	SAHIN MUSTAFA,karabulut alpaslan,kayadibi huseyin Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. (2019): 60 - 64.
MLA	SAHIN MUSTAFA,karabulut alpaslan,kayadibi huseyin Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. , 2019, ss.60 - 64.
AMA	SAHIN M,karabulut a,kayadibi h Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. . 2019; 60 - 64.
Vancouver	SAHIN M,karabulut a,kayadibi h Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. . 2019; 60 - 64.
IEEE	SAHIN M,karabulut a,kayadibi h "Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province." , ss.60 - 64, 2019.
ISNAD	SAHIN, MUSTAFA vd. "Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province". (2019), 60-64.

APA	SAHIN M, karabulut a, kayadibi h (2019). Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. International Journal of Medical Biochemistry, 2(2), 60 - 64.
Chicago	SAHIN MUSTAFA,karabulut alpaslan,kayadibi huseyin Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. International Journal of Medical Biochemistry 2, no.2 (2019): 60 - 64.
MLA	SAHIN MUSTAFA,karabulut alpaslan,kayadibi huseyin Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. International Journal of Medical Biochemistry, vol.2, no.2, 2019, ss.60 - 64.
AMA	SAHIN M,karabulut a,kayadibi h Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. International Journal of Medical Biochemistry. 2019; 2(2): 60 - 64.
Vancouver	SAHIN M,karabulut a,kayadibi h Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province. International Journal of Medical Biochemistry. 2019; 2(2): 60 - 64.
IEEE	SAHIN M,karabulut a,kayadibi h "Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province." International Journal of Medical Biochemistry, 2, ss.60 - 64, 2019.
ISNAD	SAHIN, MUSTAFA vd. "Investigation of the distribution of thyroid dysfunction in the geriatric patient population in Corum province". International Journal of Medical Biochemistry 2/2 (2019), 60-64.