Granulomatosis with polyangitis (GPA/WG) (previously known as Wegener granulomatosis) is a multisystemsystemic necrotizing non-caeseating granulomatous vasculitis affecting small to medium sized arteries, capillaries andveins, with a predilection for the respiratory system and kidneys. The average incidence of this disease is 40-55. 90% of theWG patients have pulmonary involvement. Wegener Granulomatosis is a disease with high mortality when its diagnosisand treatment is delayed. Although WG may have symptoms such as hemoptysis and hematuria, it should be noted that itmay present with severe arthralgia and arthritis which may be in many connective tissue diseases and vasculitis. Malepatient, 52 years old. Analgesic treatment was applied when he came to the center due to arthralgia two months ago,however, there was no change in his complaints and intra-articular injection treatment was applied on left knee and bothshoulders. The symptoms did not regress and the patient lost 20 kg within the last two months. In urine analysis, 14-15erythrocyte and 10-15 leucocyte detected in every field; 1 positive detected. The patient was hospitalized in order to makefurther examination upon the determination of CRP: 61 mg/L and ESR: 82 mm/hr in the next polyclinic control after threedays. In the kidney biopsy report, “Pauci-immun glomerulonephritis” was primarily considered in the phenomenon. For thefirst three days 1 gr pulse and by the fourth day 1 mg/kg methylprednisolone and cyclophosphamide treatment was applied