A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width
Yıl: 2019 Cilt: 8 Sayı: 3 Sayfa Aralığı: 107 - 112 Metin Dili: İngilizce DOI: 10.33880/ejfm.2019080303 İndeks Tarihi: 21-04-2020
A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width
Öz: Aim: Anemia is a public health problem worldwide. Cost effectiveness and efficient use ofresources are vitally important. Red blood cell distribution width, which can be obtained from astandard complete blood count, is a measure of the variability in size of circulating erythrocytes. Thepresent study was performed to investigate whether red blood cell distribution width can be used topredict response to iron therapy.Methods: This study was conducted in 50 patients admitted to hematology and family medicineclinics. Complete blood count and reticulocyte count were determined on day 5; complete blood countwas examined 1 month after commencement of therapy.Results: Statistically significant differences were detected between hemoglobin levels and redblood cell distribution width values at the time of diagnosis and on day 5 and after 1 month of therapy.A significant positive correlation was found between the increase in red blood cell distribution widthand the increase in hemoglobin.Conclusion: Red blood cell distribution width may be used in place of reticulocyte count to predictresponse to iron therapy. Red blood cell distribution width is the best biomarker for this purpose as acomponent of complete blood count, and therefore it may be accepted as superior to reticulocyte count.
Anahtar Kelime: Konular:
Demir Eksikliği Anemisinde Terapötik Yanıtı Tahmin Etmek Için Yeni Bir Parametre: Kırmızı Kan Hücresi Dağılım Genişliği
Öz: Amaç: Anemi, dünya çapında bir halk sağlığı sorunudur. Maliyet etkinliği ve kaynakların verimli kullanımı hayati öneme sahiptir. Standart bir tam kan sayımından elde edilebilen kırmızı kan hücresi dağılım genişliği, dolaşımdaki eritrositlerin boyutundaki değişkenliğin bir ölçüsüdür. Bu çalışma kırmızı kan hücresi dağılım genişliği nin demir tedavisine yanıtı tahmin etmek için kullanılıp kullanılamayacağını araştırmak için yapıldı. Yöntem: Bu çalışma hematoloji ve aile hekimliği kliniğine başvuran 50 hastada yapıldı. Tam kan sayımı ve retikülosit sayısı 5. günde; tam kan sayımı ve kırmızı kan hücresi dağılım genişliği tedavinin başlamasından 1 ay sonra incelenmiştir. Bulgular: Hemoglobin düzeyleri ile kırmızı kan hücresi dağılım genişliği değerleri arasında tanı anında ve 5. günde ve 1. ayda tedavide istatistiksel olarak anlamlı fark bulundu. Kırmızı kan hücresi dağılım genişliğideki artış ile hemoglobindeki artış arasında anlamlı bir pozitif ilişki bulundu. Sonuç: Demir terapisine cevabı tahmin etmek için retikülosit sayısı yerine kırmızı kan hücresi dağılım genişliği kullanılabilir. Kırmızı kan hücresi dağılım genişliği, tam kan sayımının bir bileşeni olarak bu amaç için en iyi biyobelirteçtir ve bu nedenle retikülosit sayısından daha üstün olarak kabul edilebilir.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | KORUR A, AÇIK D, SOLMAZ S, Gereklioglu C, ASMA S, ÖZDOĞU H (2019). A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. , 107 - 112. 10.33880/ejfm.2019080303 |
| Chicago | KORUR ASLI,AÇIK Didar Yanardağ,SOLMAZ SONER,Gereklioglu Cigdem,ASMA Süheyl,ÖZDOĞU Hakan A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. (2019): 107 - 112. 10.33880/ejfm.2019080303 |
| MLA | KORUR ASLI,AÇIK Didar Yanardağ,SOLMAZ SONER,Gereklioglu Cigdem,ASMA Süheyl,ÖZDOĞU Hakan A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. , 2019, ss.107 - 112. 10.33880/ejfm.2019080303 |
| AMA | KORUR A,AÇIK D,SOLMAZ S,Gereklioglu C,ASMA S,ÖZDOĞU H A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. . 2019; 107 - 112. 10.33880/ejfm.2019080303 |
| Vancouver | KORUR A,AÇIK D,SOLMAZ S,Gereklioglu C,ASMA S,ÖZDOĞU H A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. . 2019; 107 - 112. 10.33880/ejfm.2019080303 |
| IEEE | KORUR A,AÇIK D,SOLMAZ S,Gereklioglu C,ASMA S,ÖZDOĞU H "A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width." , ss.107 - 112, 2019. 10.33880/ejfm.2019080303 |
| ISNAD | KORUR, ASLI vd. "A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width". (2019), 107-112. https://doi.org/10.33880/ejfm.2019080303 |
| APA | KORUR A, AÇIK D, SOLMAZ S, Gereklioglu C, ASMA S, ÖZDOĞU H (2019). A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. Eurasian Journal of Family Medicine, 8(3), 107 - 112. 10.33880/ejfm.2019080303 |
| Chicago | KORUR ASLI,AÇIK Didar Yanardağ,SOLMAZ SONER,Gereklioglu Cigdem,ASMA Süheyl,ÖZDOĞU Hakan A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. Eurasian Journal of Family Medicine 8, no.3 (2019): 107 - 112. 10.33880/ejfm.2019080303 |
| MLA | KORUR ASLI,AÇIK Didar Yanardağ,SOLMAZ SONER,Gereklioglu Cigdem,ASMA Süheyl,ÖZDOĞU Hakan A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. Eurasian Journal of Family Medicine, vol.8, no.3, 2019, ss.107 - 112. 10.33880/ejfm.2019080303 |
| AMA | KORUR A,AÇIK D,SOLMAZ S,Gereklioglu C,ASMA S,ÖZDOĞU H A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. Eurasian Journal of Family Medicine. 2019; 8(3): 107 - 112. 10.33880/ejfm.2019080303 |
| Vancouver | KORUR A,AÇIK D,SOLMAZ S,Gereklioglu C,ASMA S,ÖZDOĞU H A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width. Eurasian Journal of Family Medicine. 2019; 8(3): 107 - 112. 10.33880/ejfm.2019080303 |
| IEEE | KORUR A,AÇIK D,SOLMAZ S,Gereklioglu C,ASMA S,ÖZDOĞU H "A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width." Eurasian Journal of Family Medicine, 8, ss.107 - 112, 2019. 10.33880/ejfm.2019080303 |
| ISNAD | KORUR, ASLI vd. "A Novel Parameter for Predicting Therapeutic Response in Iron Deficiency Anemia: Red Blood Cell Distribution Width". Eurasian Journal of Family Medicine 8/3 (2019), 107-112. https://doi.org/10.33880/ejfm.2019080303 |
