Yıl: 2019 Cilt: 51 Sayı: 2 Sayfa Aralığı: 160 - 164 Metin Dili: İngilizce İndeks Tarihi: 22-04-2020

The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes

Öz:
Objective: This study aimed to compare the effects of three different hemostatic agents on surgical and early renal functional outcomes after laparoscopic partial nephrectomy (LPN).Materials and Methods: A total of 126 cases of LPN performed between November 2008 and September 2016 were enrolled in this study. Spongostan™ Absorbable Hemostatic Gelatin Sponge (Ethicon, Somerville, NJ, USA) or Surgicel® Original Absorbable Hemostat (Ethicon, Somerville, NJ, USA), or a total of 5 mL of Floseal® Hemostatic Matrix (Baxter Healthcare, Deerfield, IL) was used for additional hemostasis. According to the hemostatic agent used, patients were divided into three groups; and patient characteristics, body mass index (BMI), American Society of Anesthesiologists (ASA) score, tumor characteristics, perioperative parameters, serum creatinine levels, and complications were compared among these three groups.Results: Age, BMI, ASA score, tumor characteristics, operative time, warm ischemia time, complication rates, and length of hospital stay were similar among the groups, whereas estimated blood loss was significantly lower in the Floseal Group (p=0.01). Postoperative serum creatinine levels and differences between preoperative and postoperative serum creatinine levels were also similar among the groups.Conclusion: The type of hemostatic agent used in LPN may affect the estimated blood loss. However, it has no substantial effect on other surgical parameters and early renal functional outcomes.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Ljungberg B, Campbell SC, Choi HY, et al. The epidemiology of renal cell carcinoma. Eur Urol 2011; 60: 615-21. [CrossRef]
  • 2. Chin AI, Lam JS, Figlin RA, Belldegrun AS. Surveillance Strategies for Renal Cell Carcinoma Patients Following Nephrectomy. Rev Urol 2006; 8: 1-7.
  • 3. Zhang R, Wu G, Huang J, et al. Peritumoral Artery Scoring System: a Novel Scoring System to Predict Renal Function Outcome after Laparoscopic Partial Nephrectomy. Sci Rep 2017; 7: 2853. [CrossRef]
  • 4. Alyami FA, Rendon RA. Laparoscopic partial nephrectomy for >4 cm renal masses. Can Urol Assoc J 2013; 7: E281-6. [CrossRef]
  • 5. Springer C, Hoda MR, Fajkovic H, et al. Laparoscopic vs open partial nephrectomy for T1 renal tumours: evaluation of long-term oncological and functional outcomes in 340 patients. BJU Int 2013; 111: 281-8. [CrossRef]
  • 6. Liu Z, Wang P, Xia D, Lou YF, Pan HF, Wang S. Comparison between laparoscopic and open partial nephrectomy: surgical, oncologic, and functional outcomes. Kaohsiung J Med Sci 2013; 29: 624-8. [CrossRef]
  • 7. Breda A, Stepanian SV, Lam JS, et al. Use of haemostatic agents and glues during laparoscopic partial nephrectomy: a multi-institutional survey from the United States and Europe of 1347 cases. Eur Urol 2007; 52: 798-803. [CrossRef]
  • 8. Redshaw JD, West JM, Stephenson RA, et al. Use of a polytetrafluoroethylene (GORE-TEX) bolster to close the renal parenchymal defect during open partial nephrectomy. Urology 2014; 84: 707-11. [CrossRef]
  • 9. Porpiglia F, Bertolo R, Amparore D, Fiori C. Nephron-sparing Suture of Renal Parenchyma After Partial Nephrectomy: Which Technique to Go For? Some Best Practices. Eur Urol Focus 2017; doi: 10.1016/j.euf.2017.08.006. [Epub ahead of print]. [CrossRef]
  • 10. Kommu SS, McArthur R, Emara AM, et al. Current Status of Hemostatic Agents and Sealants in Urologic Surgical Practice. Rev Urol 2015; 17: 150-9.
  • 11. Dindo D, Demartines N, Clavien PA. Classification of Surgical Complications A New Proposal With Evaluation in a Cohort of 6336 Patients and Results of a Survey. Ann Surg 2004; 240: 205-13. [CrossRef]
  • 12. Agarwal D, O'Malley P, Clarke D, Rao R. Modified technique of renal defect closure following laparoscopic partial nephrectomy. BJU Int 2007; 100: 967-70. [CrossRef]
  • 13. Novick AC. Renal hypothermia: in vivo and ex vivo. Urol Clin North Am 1983; 10: 637-44.
  • 14. Galanakis I, Vasdev N, Soomro N. A Review of Current Hemostatic Agents and Tissue Sealants Used in Laparoscopic Partial Nephrectomy. Rev Urol 2011; 13: 131-8.
  • 15. Vyas KS, Saha SP. Comparison of hemostatic agents used in vascular surgery. Expert Opin Biol Ther 2013; 13: 1663-72. [CrossRef]
  • 16. Schreiber MA, Neveleff DJ. Achieving hemostasis with topical hemostats: making clinically and economically appropriate decisions in the surgical and trauma settings. AORN J 2011; 94: 1-20. [CrossRef]
  • 17. Carrion DM, Gregorio SA, Rivas JG, Bazan AA, Sebastian JZ, Martinez-Pineiro L. The role of hemostatic agents in preventing complications in laparoscopic partial nephrectomy. Cent European J Urol 2017; 70: 362-7.
  • 18. Lang H,Mouracade P, Gimel P, et al. National prospective study on the use of local haemostatic agents during partial nephrectomy. BJU Int 2014; 113: E56-61. [CrossRef]
  • 19. Siemer S, Lahme S, Altziebler S, et al. Efficacy and safety of TachoSil as haemostatic treatment versus standard suturing in kidney tumour resection: a randomised prospective study. Eur Urol 2007; 52: 1156-63. [CrossRef]
  • 20. Maurice MJ, Ramirez D, Kara Ö, et al. Omission of Hemostatic Agents during Robotic Partial Nephrectomy Does Not Increase Postoperative Bleeding Risk. J Endourol 2016; 30: 877-83. [CrossRef]
  • 21. Richter F, Schnorr D, Deger S, et al. Improvement of hemostasis in open and laparoscopically performed partial nephrectomy using a gelatin matrix-thrombin tissue sealant (FloSeal). Urology 2003; 61: 73-7. [CrossRef]
  • 22. Bak JB, Singh A, Shekarriz B. Use of gelatin matrix thrombin tissue sealant as an effective hemostatic agent during laparoscopic partial nephrectomy. J Urol 2004; 171: 780-2. [CrossRef]
  • 23. Pruthi RS, Chun J, Richman M. The use of a fibrin tissue sealant during laparoscopic partial nephrectomy. BJU Int 2004; 93: 813-7. [CrossRef]
  • 24. Gill IS, Ramani AP, Spaliviero M, et al. Improved hemostasis during laparoscopic partial nephrectomy using gelatin matrix thrombin sealant. Urology 2005; 65: 463-6. [CrossRef]
  • 25. Finley DS, Lee DI, Eichel L, Uribe CA, McDougall EM, Clayman RV. Fibrin glue-oxidized cellulose sandwich for laparoscopic wedge resection of small renal lesions. J Urol 2005; 173: 1477-81. [CrossRef]
  • 26. Triaca V, Zagha RM, Libertino JA. Does thrombin sealant allow nephron-sparing surgery with no renal artery occlusion? A description of technique and initial results. BJU Int 2005; 95: 1273-5. [CrossRef]
  • 27. Antonelli A, Minervini A, Mari A, et al. TriMatch comparison of the efficacy of FloSeal versus TachoSil versus no hemostatic agents for partial nephrectomy: results from a large multicenter dataset. Int J Urol 2015; 22: 47-52. [CrossRef]
  • 28. Abu-Ghanem Y, Dotan Z, Kaver I, Zilberman DE, Ramon J. The use of haemostatic agents does not impact the rate of hemorrhagic complications in patients undergoing partial nephrectomy for renal masses. Sci Rep 2016; 6: 32376. [CrossRef]
APA aykan s, temiz m, ULUS I, YILMAZ M, Gönültaş S, SÜZAN S, Semerciöz A, Muslumanoglu A (2019). The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. , 160 - 164.
Chicago aykan serdar,temiz mustafa,ULUS Ismail,YILMAZ MEHMET,Gönültaş Serkan,SÜZAN Serhat,Semerciöz Atilla,Muslumanoglu Ahmet Yaser The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. (2019): 160 - 164.
MLA aykan serdar,temiz mustafa,ULUS Ismail,YILMAZ MEHMET,Gönültaş Serkan,SÜZAN Serhat,Semerciöz Atilla,Muslumanoglu Ahmet Yaser The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. , 2019, ss.160 - 164.
AMA aykan s,temiz m,ULUS I,YILMAZ M,Gönültaş S,SÜZAN S,Semerciöz A,Muslumanoglu A The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. . 2019; 160 - 164.
Vancouver aykan s,temiz m,ULUS I,YILMAZ M,Gönültaş S,SÜZAN S,Semerciöz A,Muslumanoglu A The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. . 2019; 160 - 164.
IEEE aykan s,temiz m,ULUS I,YILMAZ M,Gönültaş S,SÜZAN S,Semerciöz A,Muslumanoglu A "The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes." , ss.160 - 164, 2019.
ISNAD aykan, serdar vd. "The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes". (2019), 160-164.
APA aykan s, temiz m, ULUS I, YILMAZ M, Gönültaş S, SÜZAN S, Semerciöz A, Muslumanoglu A (2019). The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. Eurasian Journal of Medicine, 51(2), 160 - 164.
Chicago aykan serdar,temiz mustafa,ULUS Ismail,YILMAZ MEHMET,Gönültaş Serkan,SÜZAN Serhat,Semerciöz Atilla,Muslumanoglu Ahmet Yaser The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. Eurasian Journal of Medicine 51, no.2 (2019): 160 - 164.
MLA aykan serdar,temiz mustafa,ULUS Ismail,YILMAZ MEHMET,Gönültaş Serkan,SÜZAN Serhat,Semerciöz Atilla,Muslumanoglu Ahmet Yaser The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. Eurasian Journal of Medicine, vol.51, no.2, 2019, ss.160 - 164.
AMA aykan s,temiz m,ULUS I,YILMAZ M,Gönültaş S,SÜZAN S,Semerciöz A,Muslumanoglu A The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. Eurasian Journal of Medicine. 2019; 51(2): 160 - 164.
Vancouver aykan s,temiz m,ULUS I,YILMAZ M,Gönültaş S,SÜZAN S,Semerciöz A,Muslumanoglu A The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes. Eurasian Journal of Medicine. 2019; 51(2): 160 - 164.
IEEE aykan s,temiz m,ULUS I,YILMAZ M,Gönültaş S,SÜZAN S,Semerciöz A,Muslumanoglu A "The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes." Eurasian Journal of Medicine, 51, ss.160 - 164, 2019.
ISNAD aykan, serdar vd. "The Use of Three Different Hemostatic Agents during Laparoscopic Partial Nephrectomy: A Comparison of Surgical and Early Renal Functional Outcomes". Eurasian Journal of Medicine 51/2 (2019), 160-164.