Elif BAYRAKTAR
(Erzurum Bölge Eğitim ve Araştırma Hastanesi, İç Hastalıkları Anabilim Dalı, Erzurum, Türkiye)
Pınar TOSUN TAŞAR
(Atatürk Üniversitesi, Tıp Fakültesi, Geriatri Anabilim Dalı, Erzurum, Türkiye)
Doğan Nasır BİNİCİ
(Erzurum Bölge Eğitim ve Araştırma Hastanesi, İç Hastalıkları Anabilim Dalı, Erzurum, Türkiye)
Ömer KARAŞAHİN
(Erzurum Bölge Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları Anabilim Dalı, Erzurum, Türkiye)
Özge TİMUR
(Erzurum Bölge Eğitim ve Araştırma Hastanesi, İç Hastalıkları Anabilim Dalı, Erzurum, Türkiye)
Sevnaz ŞAHİN
(Ege Üniversitesi, Tıp Fakültesi, Yüksekokulu Geriatri Anabilim Dalı ,İzmir, Türkiye)
Yıl: 2020Cilt: 52Sayı: 1ISSN: 1308-8734 / 1308-8742Sayfa Aralığı: 29 - 33İngilizce

16 0
Relationship between Sarcopenia and Mortality in Elderly Inpatients
Objective: Sarcopenia, a geriatric syndrome, is an indicator of poor prognosis in elderly inpatients. In this study, we aimed to determine the effect of sarcopenia on mortality in elderly patients. Materials and Methods: Mobile/immobile geriatric inpatients, treated in the internal medicine ward between February and November 2018, were included in the study between Days 2 and 7 of hospitalization. The patients’ fat-free mass (FFM) was measured by bioimpedance. The FFM index (FFMI) (kg/m2 ) was determined by dividing fat-free mass by body surface area (FFM/BSA). Sarcopenia was defined as a FFMI value at least two standard deviations below the gender-specific mean of normal young adults. Results: The study included 200 geriatric inpatients; 96 (48.0%) were men, and the mean age was 74.49±6.32 years. Sarcopenia was detected in 28 (14%) of the patients. Diabetes mellitus was associated with a significantly lower sarcopenia prevalence (p=0.006). The risk of sarcopenia was 9.046 times higher in malnourished patients. The sarcopenia group had more deaths (p=0.012). Conclusion: Sarcopenia in geriatric inpatients increased the length of hospital stay and mortality. Our findings may guide future studies examining the relationship between sarcopenia and mortality among elderly inpatients in other hospitals.
DergiAraştırma MakalesiErişime Açık
  • 1. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing 2010; 39: 412-23. [CrossRef]
  • 2. Landi F, Liperoti R, Russo A, et al. Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study. Clin Nutr 2012; 31: 652-8. [CrossRef]
  • 3. Morley JE. Sarcopenia in the elderly. Fam Pract 2012; 29 Suppl 1: i44-8. [CrossRef]
  • 4. Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc 2002; 50: 889-96. [CrossRef]
  • 5. Abellan van Kan G. Epidemiology and consequences of sarcopenia. J Nutr Health Aging 2009; 13: 708-12. [CrossRef]
  • 6. Volpato S, Bianchi L, Cherubini A, et al. Prevalence and clinical correlates of sarcopenia in community-dwelling older people: application of the EWGSOP definition and diagnostic algorithm. J Gerontol A Biol Sci Med Sci 2014; 69: 438-46. [CrossRef]
  • 7. Gariballa S, Alessa A. Sarcopenia: prevalence and prognostic significance in hospitalized patients. Clin Nutr 2013; 32: 772-6. [CrossRef]
  • 8. Kortebein P, Ferrando A, Lombeida J, Wolfe R, Evans WJ. Effect of 10 days of bed rest on skeletal muscle in healthy older adults. JAMA 2007; 297: 1772-4. [CrossRef]
  • 9. Iannuzzi-Sucich M, Prestwood KM, Kenny AM. Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. J Gerontol A Biol Sci Med Sci 2002; 57: M772-7. [CrossRef]
  • 10. Guigoz Y, Vellas B, Garry PJ. Assessing the nutritional status of the elderly: The Mini Nutritional Assessment as part of the geriatric evaluation. Nutr Rev 1996; 54: S59-65. [CrossRef]
  • 11. Jacelon CS. The Barthel Index and other indices of functional ability. Rehabil Nurs 1986; 11: 9-11. [CrossRef]
  • 12. Mahoney FI, Barthel DW. Functional Evaluation: The Barthel Index. Md State Med J 1965; 14: 61- 5. [CrossRef]
  • 13. Kucukdeveci AA, Yavuzer G, Tennant A, Suldur N, Sonel B, Arasil T. Adaptation of the modified Barthel Index for use in physical medicine and rehabilitation in Turkey. Scand J Rehabil Med 2000; 32: 87-92. [CrossRef]
  • 14. Executive summary of the clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. Arch Intern Med 1998; 158: 1855-67. [CrossRef]
  • 15. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40: 373-83. [CrossRef]
  • 16. Martinez BP, Batista AK, Gomes IB, Olivieri FM, Camelier FW, Camelier AA. Frequency of sarcopenia and associated factors among hospitalized elderly patients. BMC Musculoskelet Disord 2015; 16: 108. [CrossRef]
  • 17. Martone AM, Bianchi L, Abete P, et al. The incidence of sarcopenia among hospitalized older patients: results from the Glisten study. J Cachexia Sarcopenia Muscle 2017; 8: 907-14. [CrossRef]
  • 18. Landi F, Cruz-Jentoft AJ, Liperoti R, et al. Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study. Age Ageing 2013; 42: 203-9. [CrossRef]
  • 19. Bianchi L, Ferrucci L, Cherubini A, et al. The Predictive Value of the EWGSOP Definition of Sarcopenia: Results From the InCHIANTI Study. J Gerontol A Biol Sci Med Sci 2016; 71: 259-64. [CrossRef]
  • 20. Atkins JL, Whincup PH, Morris RW, Lennon LT, Papacosta O, Wannamethee SG. Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men. J Am Geriatr Soc 2014; 62: 253-60. [CrossRef]
  • 21. Yalcin A, Aras S, Atmis V, et al. Sarcopenia and mortality in older people living in a nursing home in Turkey. Geriatr Gerontol Int 2017 Jul; 17: 1118-24. [CrossRef]
  • 22. Toptas M, Yalcin M, Akkoc I, et al. The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit. Biomed Res Int 2018; 2018: 5263208. [CrossRef]
  • 23. Cruz-Jentoft AJ, Landi F, Schneider SM, et al. Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing 2014; 43: 748-59. [CrossRef]

TÜBİTAK ULAKBİM Ulusal Akademik Ağ ve Bilgi Merkezi Cahit Arf Bilgi Merkezi © 2019 Tüm Hakları Saklıdır.