Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss
Yıl: 2019 Cilt: 26 Sayı: 4 Sayfa Aralığı: 463 - 469 Metin Dili: İngilizce DOI: 10.5505/vtd.2019.05826 İndeks Tarihi: 30-06-2020
Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss
Öz: Introduction: To perform retinal nerve fibre layer(RNFL) analysis in patients with age-related hearing loss(ARHL) using optical coherence tomography (OCT).Materials and Methods: Sixty-five patients with ARHLand 36 healthy controls were included in this prospectivestudy. Patients with ARHL were divided into twogroups—one with mild (33 patients) and one withmoderate (32 patients) impairment. A completeophthalmological examination was applied to all subjectsand included best-corrected visual acuity, slit lampexamination, Goldmann applanation tonometer, visualfield testing and dilated fundus examination. The RNFLthickness of all participants was measured using an OCTdevice. Pure tone audiometry tests were performed onthe patients using headphones and AC40 audiometry in asilent cabin.Results: The mean age was 70.39, 70.55 and 71.22 in thecontrol, mild and moderate hearing loss groups,respectively. A statistically significant difference wasobserved between the control group and patients withmoderate ARHL, between inferior quadrantthicknesses(p=0.011) and between mean RNFLthicknesses(p=0.025). The superior, nasal and temporalquadrant RNFL thicknesses were similar across thewhole study group, with no statistically significantdifference (p values: 0.104, 0.650, 0.470, respectively).Conclusion: The average RNFL was significantly thinnerin the patients with moderate ARHL compared to thecontrols. As age and the degree of hearing loss inc reases,RNFL thicknesses decreases.
Anahtar Kelime: Yaşa Bağlı İşitme Kaybı Olan Hastalarda Retina Sinir Lifi Kalınlığının Değerlendirilmesi
Öz: Amaç: Yaşa bağlı işitme kaybı (YBİK) olan hastalarda optik koherens tomografi (OKT) kullanarak retina sinir lifi tabakası (RSLT) kalınlığı analizi yapmak. Gereçler ve Yöntem: Bu prospektif çalışmada YBİK olan 65 hasta ve 36 sağlıklı kontrol vardı. YBİK olan hastalar hafif (33 hasta) ve orta (32 hasta) olarak iki gruba ayrıldı. Her hastaya en iyi düzeltilmiş görme keskinliği, yarıklı lamba muayenesi, Goldmann aplanasyon tonometresi, görme alanı testi ve dilate fundus muayenesi dahil olmak üzere tam bir oftalmolojik muayene yapıldı. Tüm katılımcıların RSLT kalınlığı OKT cihazı kullanılarak ölçüldü. Hastaların saf ses odyometri testleri sessiz bir kabinde kulaklık ve AC40 odyometri kullanılarak yapıldı. Bulgular: Kontrol, hafif ve orta işitme kaybı gruplarında ortalama yaş sırasıyla 70.39, 70.55 ve 71.22 idi. Kontrol grubu ve orta derecede YBİK olan hastalarda inferior kadran kalınlıkları arasında(p = 0.011) ve ortalama RSLT kalınlıkları arasında(p = 0.025) istatistiksel olarak anlamlı bir fark vardı. Üst, nazal ve temporal kadran RSLT kalınlıkları tüm çalışma gruplarında benzer bulundu ve istatistiksel olarak anlamlı bir fark yoktu (sırasıyla p =0.104, 0.650, 0.470). Sonuç: Orta derecede YBİK olan hastalarda kontrollere kıyasla ortalama RSLT kalınlıkları anlamlı derecede daha ince bulundu. Yaş ve işitme kaybı derecesi arttıkça RSLT kalınlıkları azalır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Cruickshanks KJ, Wiley TL, Tweed TS, Klein BE, Klein R, Mares-Perlman JA, et al. Prevalence of hearing loss in older adults in Beaver Dam, Wisconsin. The Epidemiology of Hearing Loss Study. American journal of epidemiology 1998; 148(9): 879-886.
- 2. Fetoni AR, Picciotti PM, Paludetti G, Troiani D. Pathogenesis of presbycusis in animal models: a review. Experimental gerontology 2011; 46(6): 413-425.
- 3. Gates GA, Mills JH. Presbycusis. Lancet 2005; 366(9491): 1111-1120.
- 4. Reiss M, Reiss G. [Presbycusis: pathogenesis and treatment]. Medizinische Monatsschrift fur Pharmazeuten 2009; 32(6): 221-225.
- 5. El-Sayyad HI, Khalifa SA, El-Sayyad FI, AlGebaly AS, El-Mansy AA, Mohammed EA. Aging-related changes of optic nerve of Wistar albino rats. Age (Dordrecht, Netherlands) 2014; 36(2): 519-532.
- 6. Morrison JC, Dorman-Pease ME, Dunkelberger GR, Quigley HA. Optic nerve head extracellular matrix in primary optic atrophy and experimental glaucoma. Archives of ophthalmology 1990; 108(7): 1020-1024.
- 7. Downs JC. Optic nerve head biomechanics in aging and disease. Experimental eye research. 2015; 133: 19-29.
- 8. Steinhart MR, Cone-Kimball E, Nguyen C, Nguyen TD, Pease ME, Chakravarti S, et al. Susceptibility to glaucoma damage related to age and connective tissue mutations in mice. Experimental eye research 2014; 119: 54-60.
- 9. Davidson JGS, Guthrie DM. Older Adults With a Combination of Vision and Hearing Impairment Experience Higher Rates of Cognitive Impairment, Functional Dependence, and Worse Outcomes Across a Set of Quality Indicators. Journal of aging and health 2017: 898264317723407.
- 10. Sung KR, Wollstein G, Bilonick RA, Townsend KA, Ishikawa H, Kagemann L, et al. Effects of age on optical coherence tomography measurements of healthy retinal nerve fiber layer, macula, and optic nerve head. Ophthalmology 2009; 116(6): 1119-1124.
- 11. Ehlers N, Hjortdal J. Corneal thickness: measurement and implications. Experimental eye research 2004; 78(3): 543-548.
- 12. Lupsakko T, Mantyjarvi M, Kautiainen H, Sulkava R. Combined hearing and visual impairment and depression in a population aged 75 years and older. International journal of geriatric psychiatry 2002; 17(9): 808-813.
- 13. Campbell VA, Crews JE, Moriarty DG, Zack MM, Blackman DK. Surveillance for sensory impairment, activity limitation, and health-related quality of life among older adults--United States, 1993-1997. MMWR CDC surveillance summaries : Morbidity and mortality weekly report CDC surveillance summaries 1999; 48(8): 131-156.
- 14. Chia EM, Mitchell P, Rochtchina E, Foran S, Golding M, Wang JJ. Association between vision and hearing impairments and their combined effects on quality of life. Archives of ophthalmology 2006; 124(10): 1465-1470.
- 15. Bozkurt MK, Ozturk BT, Kerimoglu H, Ersan I, Arbag H, Bozkurt B. Association of age-related macular degeneration with age-related hearing loss. The Journal of laryngology and otology 2011; 125(3): 231-235.
- 16. Ghasemi H, Pourakbari MS, Entezari M, Yarmohammadi ME. Association of Age Related Macular Degeneration and Age Related Hearing Impairment. Journal of ophthalmic & vision research 2016; 11(1): 54-60.
- 17. Mujica-Mota MA, Schermbrucker J, Daniel SJ. Eye color as a risk factor for acquired sensorineural hearing loss: a review. Hearing research 2015; 320: 1-10.
- 18. Papadopoulos TA, Naxakis SS, Charalabopoulou M, Vathylakis I, Goumas PD, Gartaganis SP. Exfoliation syndrome related to sensorineural hearing loss. Clin Exp Ophthalmol 2010; 38(5): 456-461.
- 19. Todd NW, Alvarado CS, Brewer DB. Cisplatin in children: hearing loss correlates with iris and skin pigmentation. The Journal of laryngology and otology 1995; 109(10): 926-929.
- 20. Klaver CC, Wolfs RC, Vingerling JR, Hofman A, de Jong PT. Age-specific prevalence and causes of blindness and visual impairment in an older population: the Rotterdam Study. Archives of ophthalmology 1998; 116(5): 653-658.
- 21. Jeoung JW, Park KH, Kim TW, Khwarg SI, Kim DM. Diagnostic ability of optical coherence tomography with a normative database to detect localized retinal nerve fiber layer defects. Ophthalmology 2005; 112(12): 2157-2163.
- 22. Wu Z, Saunders LJ, Zangwill LM, Daga FB, Crowston JG, Medeiros FA. Impact of Normal Aging and Progression Definitions on the Specificity of Detecting Retinal Nerve Fiber Layer Thinning. American journal of ophthalmology 2017; 181: 106-113.
- 23. Jamison DT, Breman JG, Measham AR, et al. Disease Control Priorities in Developing Countries. 2nd ed. New York, NY: Oxford University Press; 2006.
| APA | Fındık H, Çeliker M (2019). Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. , 463 - 469. 10.5505/vtd.2019.05826 |
| Chicago | Fındık Hüseyin,Çeliker Metin Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. (2019): 463 - 469. 10.5505/vtd.2019.05826 |
| MLA | Fındık Hüseyin,Çeliker Metin Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. , 2019, ss.463 - 469. 10.5505/vtd.2019.05826 |
| AMA | Fındık H,Çeliker M Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. . 2019; 463 - 469. 10.5505/vtd.2019.05826 |
| Vancouver | Fındık H,Çeliker M Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. . 2019; 463 - 469. 10.5505/vtd.2019.05826 |
| IEEE | Fındık H,Çeliker M "Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss." , ss.463 - 469, 2019. 10.5505/vtd.2019.05826 |
| ISNAD | Fındık, Hüseyin - Çeliker, Metin. "Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss". (2019), 463-469. https://doi.org/10.5505/vtd.2019.05826 |
| APA | Fındık H, Çeliker M (2019). Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. Van Tıp Dergisi, 26(4), 463 - 469. 10.5505/vtd.2019.05826 |
| Chicago | Fındık Hüseyin,Çeliker Metin Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. Van Tıp Dergisi 26, no.4 (2019): 463 - 469. 10.5505/vtd.2019.05826 |
| MLA | Fındık Hüseyin,Çeliker Metin Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. Van Tıp Dergisi, vol.26, no.4, 2019, ss.463 - 469. 10.5505/vtd.2019.05826 |
| AMA | Fındık H,Çeliker M Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. Van Tıp Dergisi. 2019; 26(4): 463 - 469. 10.5505/vtd.2019.05826 |
| Vancouver | Fındık H,Çeliker M Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss. Van Tıp Dergisi. 2019; 26(4): 463 - 469. 10.5505/vtd.2019.05826 |
| IEEE | Fındık H,Çeliker M "Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss." Van Tıp Dergisi, 26, ss.463 - 469, 2019. 10.5505/vtd.2019.05826 |
| ISNAD | Fındık, Hüseyin - Çeliker, Metin. "Evaluation of Retinal Nerve Fiber Layer Thickness in Patients with Age-Related Hearing Loss". Van Tıp Dergisi 26/4 (2019), 463-469. https://doi.org/10.5505/vtd.2019.05826 |
