Yıl: 2019 Cilt: 6 Sayı: 4 Sayfa Aralığı: 308 - 313 Metin Dili: İngilizce DOI: 10.4274/jus.galenos.2019.2612 İndeks Tarihi: 26-06-2020

Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men

Öz:
Objective: To evaluate the benefits of functional constipation (FC) management in male patients with male lower urinary tract symptoms (LUTS)coexisting with FC.Materials and Methods: We conducted a prospective study including 1748 men over the age of 40 who were admitted to our clinic withnewly diagnosed male LUTS. The patients were evaluated by history, International Prostate Symptom Score (IPSS), uroflowmetry, urinalysis, serumprostate-specific antigen testing, measurement of prostate volume by ultrasonography and post-void residual urine volume. Rectal fleet enema wasadministered in patients with FC diagnosed according to the Rome III criteria. Uroflowmetry tests were repeated 12 hours after enema. The patientswere re-evaluated after treatment with oral sennoside once a day for a month.Results: At the end of the 1 st month, 62 patients with male LUTS and FC were re-evaluated. The difference between maximum flow rate Qmaxvalues before the treatment of constipation and in the 1 st month after the treatment was statistically significant (p<0.001). There was a significantdifference between the IPSS values before and at the 1 st month after the treatment (p<0.001). The difference between the voided volumes inthe 1st month following constipation treatment and those before the treatment and on the 1 st day after treatment was statistically significant(p=0.003 and p=0.006, respectively). The difference between quality of life scores of the patients before and at the first month after treatment wasstatistically significant (p<0.001).Conclusion: Treatment of FC in patients with LUTS coexisting with FC may decrease IPSS scores, increase uroflowmetry parameters and patient’squality of life. Thus, LUTS patients with FC will be protected from unnecessary medical and surgical treatments.
Anahtar Kelime:

Erkeklerde Kronik Konstipasyonun Alt Üriner Sistem Semptomları ve Üroflowmetri Parametreleri Üzerine Etkisi

Öz:
Amaç: Alt üriner sistem semptomları (AÜSS) ve eşzamanlı fonksiyonel kabızlığı (FK) olan erkeklerde fonksiyonel kabızlığı tedavi etmenin faydalarını değerlendirmektir. Gereç ve Yöntem: Yeni tanı alan AÜSS ile kliniğimize başvuran 40 yaş üzeri 1748 erkek hasta prospektif olarak çalışmaya dahil edildi. Hastalar; özgeçmiş, IPSS, üroflovmetri, idrar analizi, serum prostat spesifik antijen tayini, üriner sistem ultrasonografisi yardımı ile prostat hacmi ve işeme sonrası artık idrar volümü ölçümü ile değerlendirildi. Roma III kriterlerine göre tanı konan FK hastalarına rektal lavman uygulandı. Hastalar bir ay boyunca günde bir kez oral sennoside ile tedaviden sonra tekrar değerlendirildi. Bulgular: Birinci ayın sonunda erkek alt üriner sistem şikayetleri ve FK olan 62 hasta yeniden değerlendirildi. Kabızlık tedavisinden önceki ve tedaviden sonra 1. aydaki Qmax değerleri arasındaki fark istatistiksel olarak anlamlıydı (p<0,001). Tedavi öncesi ve tedavi sonrası birinci aydaki IPSS değerleri arasında anlamlı fark vardı (p<0,001). Kabızlık tedavisini takiben 1. aydaki idrar hacimleri ile tedavi öncesi idrar hacmi (p=0,003) ve 1. gün idrar hacimleri (p=0,006) arasında anlamlı farklılıklar mevcut idi. Hastaların tedavi öncesi ve tedavi sonrası birinci aydaki yaşam kalitesi puanları arasındaki istatistiksel olarak anlamlı fark mevcuttu (p<0,001). Sonuç: Eş zamanlı AÜSS ve fonksiyonel kabızlığı olan hastalarda; fonksiyonel kabızlığın tedavisi total IPSS değerlerinde azalmaya, üroflovmetre parametrelerinde ve hasta yaşam kalitesi değerlerinde artmaya neden olabilir buna bağlı olarak da hastalar gereksiz cerrahi ve medikal tedavilerden korunabilir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Speakman M, Kirby R, Doyle S, Ioannou C. Burden of male lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) - focus on the UK. BJU Int 2015;115:508-519.
  • 2. C Coyne KS, Kaplan SA, Chapple CR, Sexton CC, Kopp ZS, Bush EN, Aiyer LP; EpiLUTS Team. Risk factors and comorbid conditions associated with lower urinary tract symptoms: EpiLUTS. BJU Int 2009;103:24-32.
  • 3. McGrath KH, Caldwell PH, Jones MP. The frequency of constipation in children with nocturnal enuresis: a comparison with parental reporting. J Paediatr Child Health 2008;44:19-27.
  • 4. Carter D, Beer-Gabel M. Lower urinary tract symptoms in chronically constipated women. Int Urogynecol J 2012;23:1785-1789.
  • 5. Chrzan R, Klijn AJ, Vijverberg MA, Sikkel F, de Jong TP. Colonic washout enemas for persistent constipation in children with recurrent urinary tract infections based on dysfunctional voiding. Urology 2008;71:607-610.
  • 6. Loening-Baucke V. Urinary incontinence and urinary tract infection and their resolution with treatment of chronic constipation of childhood. Pediatrics 1997;100:228-232.
  • 7. Soligo M, Salvatore S, Emmanuel AV, De Ponti E, Zoccatelli M, Cortese M, Milani R. Patterns of constipation in urogynecology: clinical importance and pathophysiologic insights. Am J Obstet Gynecol 2006;195:50-55.
  • 8. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006;130:1480-1491.
  • 9. Charach G, Greenstein A, Rabinovich P, Groskopf I, Weintraub M. Alleviating constipation in the elderly improves lower urinary tract symptoms. Gerontology 2001;47:72-76.
  • 10. Mearin F, Lacy BE. Diagnostic criteria in IBS: useful or not? Neurogastroenterol Motil 2012;24:791-801.
  • 11. Burgers RE, Mugie SM, Chase J, Cooper CS, von Gontard A, Rittig CS, Homsy Y, Bauer SB, Benninga MA. Management of functional constipation in children with lower urinary tract symptoms: report from the Standardization Committee of the International Children’s Continence Society. J Urol 2013;190:29-36.
  • 12. Koskimäki J, Hakama M, Huhtala H, Tammela TL. Association of nonurological diseases with lower urinary tract symptoms. Scand J Urol Nephrol 2001;35:377-381.
  • 13. Kaplan SA, Dmochowski R, Cash BD, Kopp ZS, Berriman SJ, Khullar V. Systematic review of the relationship between bladder and bowel function: implications for patient management. Int J Clin Pract 2013;67:205-216.
  • 14. Zantl N, Hartung R. TUR-Related Complications. In: Hohenfellner M, Santucci RA editors. Emergencies in Urology. Berlin: Springer, 2007:335- 348.
  • 15. Rieken M, Ebinger Mundorff N, Bonkat G, Wyler S, Bachmann A. Complications of laser prostatectomy: a review of recent data. World J Urol 2010;28:53-62.
  • 16. Nickel JC. BPH: costs and treatment outcomes. Am J Manag Care 2006;12:141-148.
  • 17. Gacci M, Corona G, Vignozzi L, Salvi M, Serni S, De Nunzio C, Tubaro A, Oelke M, Carini M, Maggi M. Metabolic syndrome and benign prostatic enlargement: a systematic review and meta-analysis. BJU Int 2015;115:24- 31.
  • 18. Averbeck MA, Madersbacher H. Constipation and LUTS - how do they affect each other? Int Braz J Urol 2011;37:16-28.
  • 19. Chase JW, Homsy Y, Siggaard C, Sit F, Bower WF. Functional constipation in children. J Urol 2004;171:2641-2643.
  • 20. Saga S, Vinsnes AG, Mørkved S, Norton C, Seim A. What characteristics predispose to continence in nursing home residents?: a population-based cross-sectional study. Neurourol Urodyn 2015;34:362-367.
APA YONGUC T, Şen V, BOZKURT H, Aydin M, polat s, Yarimoglu S (2019). Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. , 308 - 313. 10.4274/jus.galenos.2019.2612
Chicago YONGUC TARIK,Şen Volkan,BOZKURT Halil İbrahim,Aydin Mehmet Erhan,polat salih,Yarimoglu Serkan Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. (2019): 308 - 313. 10.4274/jus.galenos.2019.2612
MLA YONGUC TARIK,Şen Volkan,BOZKURT Halil İbrahim,Aydin Mehmet Erhan,polat salih,Yarimoglu Serkan Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. , 2019, ss.308 - 313. 10.4274/jus.galenos.2019.2612
AMA YONGUC T,Şen V,BOZKURT H,Aydin M,polat s,Yarimoglu S Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. . 2019; 308 - 313. 10.4274/jus.galenos.2019.2612
Vancouver YONGUC T,Şen V,BOZKURT H,Aydin M,polat s,Yarimoglu S Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. . 2019; 308 - 313. 10.4274/jus.galenos.2019.2612
IEEE YONGUC T,Şen V,BOZKURT H,Aydin M,polat s,Yarimoglu S "Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men." , ss.308 - 313, 2019. 10.4274/jus.galenos.2019.2612
ISNAD YONGUC, TARIK vd. "Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men". (2019), 308-313. https://doi.org/10.4274/jus.galenos.2019.2612
APA YONGUC T, Şen V, BOZKURT H, Aydin M, polat s, Yarimoglu S (2019). Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. Journal of Urological Surgery, 6(4), 308 - 313. 10.4274/jus.galenos.2019.2612
Chicago YONGUC TARIK,Şen Volkan,BOZKURT Halil İbrahim,Aydin Mehmet Erhan,polat salih,Yarimoglu Serkan Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. Journal of Urological Surgery 6, no.4 (2019): 308 - 313. 10.4274/jus.galenos.2019.2612
MLA YONGUC TARIK,Şen Volkan,BOZKURT Halil İbrahim,Aydin Mehmet Erhan,polat salih,Yarimoglu Serkan Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. Journal of Urological Surgery, vol.6, no.4, 2019, ss.308 - 313. 10.4274/jus.galenos.2019.2612
AMA YONGUC T,Şen V,BOZKURT H,Aydin M,polat s,Yarimoglu S Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. Journal of Urological Surgery. 2019; 6(4): 308 - 313. 10.4274/jus.galenos.2019.2612
Vancouver YONGUC T,Şen V,BOZKURT H,Aydin M,polat s,Yarimoglu S Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men. Journal of Urological Surgery. 2019; 6(4): 308 - 313. 10.4274/jus.galenos.2019.2612
IEEE YONGUC T,Şen V,BOZKURT H,Aydin M,polat s,Yarimoglu S "Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men." Journal of Urological Surgery, 6, ss.308 - 313, 2019. 10.4274/jus.galenos.2019.2612
ISNAD YONGUC, TARIK vd. "Impact of Chronic Constipation on Lower Urinary Tract Symptoms and Uroflowmetry Parameters in Men". Journal of Urological Surgery 6/4 (2019), 308-313. https://doi.org/10.4274/jus.galenos.2019.2612