Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction

Öz:

Introduction: Previous studies reported that inflammatory markers are associated with the development ofnew-onset atrial fibrillation (NOAF) in patients with coronary artery disease. However, the predictive value ofserum C-reactive protein (CRP) to serum albumin ratio (CAR) for the development of NOAF in patients withST elevation myocardial infarction (STEMI) has not been investigated yet. Hence, the aim of the present studywas to evaluate the potential utility of the CAR in predicting NOAF in patients with STEMI who underwentprimary percutaneous coronary intervention (pPCI).Patients and Methods: The present study was a retrospective analysis of the data related to 1153 patients withSTEMI who underwent pPCI. CRP levels were measured according to the immunoturbidimetric method, andserum albumin levels were analyzed by the bromocresol green method. The CAR was defined as the serumCRP level divided by the serum albumin level.Results: The incidence of NOAF during in-hospital stay was 5.2% (n= 62 patients). Patients with NOAF hadhigher CAR values than those without NOAF. Multivariate logistic regression analyses revealed that elevatedCAR value was an independent predictor of NOAF (odds ratio 3.280, 95% confidence interval 1.564-6.878;p= 0.002). Furthermore, comparison of receiver operating characteristic curves yielded that the predictive performance of CAR was higher than CRP and albumin alone, respectively.Conclusion: In the present study, we observed that elevated CAR values were independently associated withNOAF development in patients with STEMI treated with pPCI.

Anahtar Kelime:

ST Yükselmeli Miyokart İnfarktüslü Hastalarda C-Reaktif Protein/Albumin Oranı ile Yeni Başlangıçlı Atriyal Fibrilasyon Arasındaki İlişkinin Değerlendirilmesi

Öz:

Giriş: Daha önceden yapılan çalışmalar, inflamatuvar belirteçlerin koroner arter hastalığı olan hastalarda yeni başlayan atriyal fibrilasyon (AF)’un gelişimi ile ilişkili olduğunu göstermiştir. Bununla birlikte, ST yükselmeli miyokart infarktüslü (STEMİ) hastalarda AF gelişimi için serum C-reaktif protein (CRP)’in serum albumin oranı (CAR)’na göre prediktif değeri henüz araştırılmamıştır. Bu nedenle, bu çalışmada, primer perkütan koroner girişim (pPKG) yapılan STEMİ hastalarında AF’ı öngörmedeki değerini değerlendirmeyi amaçladık. Hastalar ve Yöntem: Bu çalışma, pPKG uygulanan 1153 STEMİ hastasına ilişkin verilerin geriye yönelik analiz edilmesi ile yapıldı. CRP düzeyleri immünoturbidimetrik yönteme göre ölçüldü ve serum albumin düzeyleri bromkresol yeşili yöntemiyle analiz edildi. CAR, CRP değerlerinin serum albumin oranı olarak tanımlandı. Bulgular: Hastanede kalış sırasında AF insidansı %5.2 (n= 62 hasta) idi. AF olan hastalar, AF olmayanlara kıyasla yüksek CAR değerlerine sahipti. Çok değişkenli lojistik regresyon analizleri, yüksek CAR değerinin AF’ın bağımsız bir belirleyicisi olduğunu ortaya koydu (OR: 3.280, %95 CI: 1.564-6.878; p= 0.002). Ayrıca, ROC curve eğrilerinin karşılaştırıldığında, CAR’ın öngörücü performansının sırasıyla CRP ve albuminden daha yüksek olduğunu göstermiştir. Sonuç: Bu çalışmada pPKG ile tedavi edilen STEMİ hastalarında yüksek CAR değerlerinin AF gelişimi ile bağımsız olarak ilişkili olduğunu gözlemledik.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Yesin M, ÇAĞDAŞ M, karabağ y, RENCÜZOĞULLARI İ, KALÇIK M, Burak C, Cinar T, Karakoyun S, GÜRSOY O, TANBOĞA İ (2019). Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. , 100 - 106. 10.5578/khj.68260
Chicago	Yesin Mahmut,ÇAĞDAŞ Metin,karabağ yavuz,RENCÜZOĞULLARI İbrahim,KALÇIK Macit,Burak Cengiz,Cinar Tufan,Karakoyun Süleyman,GÜRSOY Ozan Mustafa,TANBOĞA İbrahim Halil Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. (2019): 100 - 106. 10.5578/khj.68260
MLA	Yesin Mahmut,ÇAĞDAŞ Metin,karabağ yavuz,RENCÜZOĞULLARI İbrahim,KALÇIK Macit,Burak Cengiz,Cinar Tufan,Karakoyun Süleyman,GÜRSOY Ozan Mustafa,TANBOĞA İbrahim Halil Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. , 2019, ss.100 - 106. 10.5578/khj.68260
AMA	Yesin M,ÇAĞDAŞ M,karabağ y,RENCÜZOĞULLARI İ,KALÇIK M,Burak C,Cinar T,Karakoyun S,GÜRSOY O,TANBOĞA İ Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. . 2019; 100 - 106. 10.5578/khj.68260
Vancouver	Yesin M,ÇAĞDAŞ M,karabağ y,RENCÜZOĞULLARI İ,KALÇIK M,Burak C,Cinar T,Karakoyun S,GÜRSOY O,TANBOĞA İ Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. . 2019; 100 - 106. 10.5578/khj.68260
IEEE	Yesin M,ÇAĞDAŞ M,karabağ y,RENCÜZOĞULLARI İ,KALÇIK M,Burak C,Cinar T,Karakoyun S,GÜRSOY O,TANBOĞA İ "Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction." , ss.100 - 106, 2019. 10.5578/khj.68260
ISNAD	Yesin, Mahmut vd. "Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction". (2019), 100-106. https://doi.org/10.5578/khj.68260

APA	Yesin M, ÇAĞDAŞ M, karabağ y, RENCÜZOĞULLARI İ, KALÇIK M, Burak C, Cinar T, Karakoyun S, GÜRSOY O, TANBOĞA İ (2019). Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. Koşuyolu Heart Journal, 22(2), 100 - 106. 10.5578/khj.68260
Chicago	Yesin Mahmut,ÇAĞDAŞ Metin,karabağ yavuz,RENCÜZOĞULLARI İbrahim,KALÇIK Macit,Burak Cengiz,Cinar Tufan,Karakoyun Süleyman,GÜRSOY Ozan Mustafa,TANBOĞA İbrahim Halil Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. Koşuyolu Heart Journal 22, no.2 (2019): 100 - 106. 10.5578/khj.68260
MLA	Yesin Mahmut,ÇAĞDAŞ Metin,karabağ yavuz,RENCÜZOĞULLARI İbrahim,KALÇIK Macit,Burak Cengiz,Cinar Tufan,Karakoyun Süleyman,GÜRSOY Ozan Mustafa,TANBOĞA İbrahim Halil Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. Koşuyolu Heart Journal, vol.22, no.2, 2019, ss.100 - 106. 10.5578/khj.68260
AMA	Yesin M,ÇAĞDAŞ M,karabağ y,RENCÜZOĞULLARI İ,KALÇIK M,Burak C,Cinar T,Karakoyun S,GÜRSOY O,TANBOĞA İ Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. Koşuyolu Heart Journal. 2019; 22(2): 100 - 106. 10.5578/khj.68260
Vancouver	Yesin M,ÇAĞDAŞ M,karabağ y,RENCÜZOĞULLARI İ,KALÇIK M,Burak C,Cinar T,Karakoyun S,GÜRSOY O,TANBOĞA İ Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction. Koşuyolu Heart Journal. 2019; 22(2): 100 - 106. 10.5578/khj.68260
IEEE	Yesin M,ÇAĞDAŞ M,karabağ y,RENCÜZOĞULLARI İ,KALÇIK M,Burak C,Cinar T,Karakoyun S,GÜRSOY O,TANBOĞA İ "Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction." Koşuyolu Heart Journal, 22, ss.100 - 106, 2019. 10.5578/khj.68260
ISNAD	Yesin, Mahmut vd. "Assessment of the Relationship Between C-Reactive Protein to Albumin Ratio and New-Onset Atrial Fibrillation in Patients with ST Elevation Myocardial Infarction". Koşuyolu Heart Journal 22/2 (2019), 100-106. https://doi.org/10.5578/khj.68260