Yıl: 2019 Cilt: 23 Sayı: 1 Sayfa Aralığı: 25 - 33 Metin Dili: İngilizce DOI: 10.12991/jrp.2018.105 İndeks Tarihi: 12-06-2020

Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques

Öz:
Electrochemical polymerization was carried out in a one-compartment cell containing deaerated acetonitrile, and 100 mM tetrabutylammonium tetrafluoroborate monomer of 3-methylthiophene. The polymer films were grown on a gold electrode by bulk electrolysis at 1.700 V (vs. Ag/Ag+). The modified sensor showed an excellent electrocatalytic effect towards oxidation of the mixture of 3,4-dihydroxyphenylacetic acid (DOPAC), ascorbic acid and uric acid, which appeared at a pH range of 2-11 by differential pulse voltammetry (DPV ) techniques. The best results for determination of DOPAC were obtained by DPV in PBS (pH 7.00). A calibration curve was obtained in the DOPAC concentration range of 1.0-50.0 μM (r = 0.9948). Limit of detection and limit of quantification were found as 0.066 μM and 0.220 μM, respectively. The results of the experiments indicated that the sensor has good stability, sensitivity and reproducibility for at least one month if stored in dry air.
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APA KUYUMCU SAVAN E, ERDOĞDU G (2019). Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. , 25 - 33. 10.12991/jrp.2018.105
Chicago KUYUMCU SAVAN EBRU,ERDOĞDU GAMZE Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. (2019): 25 - 33. 10.12991/jrp.2018.105
MLA KUYUMCU SAVAN EBRU,ERDOĞDU GAMZE Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. , 2019, ss.25 - 33. 10.12991/jrp.2018.105
AMA KUYUMCU SAVAN E,ERDOĞDU G Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. . 2019; 25 - 33. 10.12991/jrp.2018.105
Vancouver KUYUMCU SAVAN E,ERDOĞDU G Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. . 2019; 25 - 33. 10.12991/jrp.2018.105
IEEE KUYUMCU SAVAN E,ERDOĞDU G "Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques." , ss.25 - 33, 2019. 10.12991/jrp.2018.105
ISNAD KUYUMCU SAVAN, EBRU - ERDOĞDU, GAMZE. "Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques". (2019), 25-33. https://doi.org/10.12991/jrp.2018.105
APA KUYUMCU SAVAN E, ERDOĞDU G (2019). Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. Journal of research in pharmacy (online), 23(1), 25 - 33. 10.12991/jrp.2018.105
Chicago KUYUMCU SAVAN EBRU,ERDOĞDU GAMZE Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. Journal of research in pharmacy (online) 23, no.1 (2019): 25 - 33. 10.12991/jrp.2018.105
MLA KUYUMCU SAVAN EBRU,ERDOĞDU GAMZE Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. Journal of research in pharmacy (online), vol.23, no.1, 2019, ss.25 - 33. 10.12991/jrp.2018.105
AMA KUYUMCU SAVAN E,ERDOĞDU G Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. Journal of research in pharmacy (online). 2019; 23(1): 25 - 33. 10.12991/jrp.2018.105
Vancouver KUYUMCU SAVAN E,ERDOĞDU G Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques. Journal of research in pharmacy (online). 2019; 23(1): 25 - 33. 10.12991/jrp.2018.105
IEEE KUYUMCU SAVAN E,ERDOĞDU G "Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques." Journal of research in pharmacy (online), 23, ss.25 - 33, 2019. 10.12991/jrp.2018.105
ISNAD KUYUMCU SAVAN, EBRU - ERDOĞDU, GAMZE. "Poly(3-methylthiophene) modified gold sensor for determination of 3,4-dihydroxyphenylacetic acid, ascorbic acid and uric acid in biological fluids using voltammetric techniques". Journal of research in pharmacy (online) 23/1 (2019), 25-33. https://doi.org/10.12991/jrp.2018.105