Yıl: 2020 Cilt: 7 Sayı: 2 Sayfa Aralığı: 112 - 117 Metin Dili: İngilizce DOI: 10.14744/nci.2019.47374 İndeks Tarihi: 17-09-2020

Could platelet distribution width predict coronary collateral development in stable coronary artery disease?

Öz:
OBJECTIVE: We hypothesized that hemogram parameters should be related to the development of coronary collateral vessels. For this purpose, we aimed to compare platelet distribution width (PDW) and PDW to platelet ratio (PPR) in subjects withstable coronary artery disease having adequate or inadequate coronary collateral development.METHODS: A total of 398 patients with stable angina pectoris undergoing coronary angiography were enrolled and dividedon the basis of the development of coronary collateral (CCD) (inadequate CCD (n=267) and adequate CCD (n=131). Routinecomplete blood count and biochemical parameters were measured before coronary arteriography.RESULTS: Mean PDW and PPR values of inadequate and adequate CCD groups were 17.5% (10–23) and 12.4% (9.8–22) %,p<0.001, respectively. In multivariate analysis, age (p=0.012, 95% CI for OR: 0.958 (0.933–0.983) and PDW (p<0.001, 95%CI for OR: 1.432 (1.252–1.618) were found to be statistically significantly different inadequate CCD group compared to adequate CCD group. Receiver operating curve (ROC) analyses revealed that a PPR value greater than 0.057 had 76% sensitivityand 51% specificity and a PDW higher than 16.2% had 80% sensitivity and 66% specificity in predicting inadequate CCD.CONCLUSION: The present study suggests that PDW and PPR may be associated with the degree of collateral developmentin chronic stable coronary artery disease (CAD).
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  • 1. Koerselman J, van der Graaf Y, de Jaegere PP, Grobbee DE. Coronary collaterals: an important and underexposed aspect of coronary artery disease. Circulation 2003;107:2507–511.
  • 2. Meier P, Gloekler S, Zbinden R, Beckh S, de Marchi SF, Zbinden S, et al. Beneficial effect of recruitable collaterals: a 10-year follow-up study in patients with stable coronary artery disease undergoing quantitative collateral measurements. Circulation 2007;116:975–83.
  • 3. Regieli JJ, Jukema JW, Nathoe HM, Zwinderman AH, Ng S, Grobbee DE, et al. Coronary collaterals improve prognosis in patients with ischemic heart disease. Int J Cardiol 2009;132:257–62.
  • 4. Nathoe HM, Koerselman J, Buskens E, van Dijk D, Stella PR, Plokker TH, et al. Octopus Study Group. Determinants and prognostic significance of collaterals in patients undergoing coronary revascularization. Am J Cardiol 2006;98:31–5.
  • 5. Teunissen PF, Horrevoets AJ, van Royen N. The coronary collateral circulation: genetic and environmental determinants in experimental models and humans. J Mol Cell Cardiol 2012;52:897–904.
  • 6. Rief P, Raggam RB, Avian A, Hafner F, Sareban M, Wehrschuetz M, et al. Low mean platelet volume is associated with critical limb ischemia in peripheral arterial occlusive disease. Sci Rep 2018;8:6718.
  • 7. Hu CP, Du Y, Zhu Y, Shi C, Qin Z, Zhao YX. Platelet Distribution Width on Admission Predicts In-Stent Restenosis in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus Treated with Percutaneous Coronary Intervention. Chin Med J (Engl) 2018;131:757–63.
  • 8. Besli F, Ilter A, Gungoren F. The Link Between Mean Platelet Volume to Lymphocyte Ratio and Complexity of Coronary Artery Disease. Angiology 2018;69(4):358–59.
  • 9. Ege MR, Guray U, Guray Y, Acıkgoz S, Demirkan B. Platelet distribution width and saphenous vein disease in patients after CABG. Association with graft occlusion. Herz 2013;38:197–201.
  • 10. Vagdatli E, Gounari E, Lazaridou E, Katsibourlia E, Tsikopoulou F, Labrianou I. Platelet distribution width: a simple, practical and specific marker of activation of coagulation. Hippokratia 2010;14:28–32.
  • 11. Matsuo K, Tang SH, Sharifi B, Rubin SA, Schreck R, Fagin JA. Growth factor production by human thyroid carcinoma cells: abundant expression of a platelet-derived growth factor-B-like protein by a human papillary carcinoma cell line. J Clin Endocrinol Metab 1993;77:996–1004.
  • 12. Purbiya P, Golwala ZM, Manchanda A, Sreenivas V, Puliyel JM. Platelet Distribution Width to Platelet Count Ratio as an Index of Severity of Illness. Indian J Pediatr 2018;85:10–4.
  • 13. Rentrop KP, Thornton JC, Feit F, Van Buskirk M. Determinants and protective potential of coronary arterial collaterals as assessed by an angioplasty model. Am J Cardiol 1988;61:677–84.
  • 14. Habib GB, Heibig J, Forman SA, Brown BG, Roberts R, Terrin ML, et al. Influence of coronary collateral vessels on myocardial infarct size in humans. Results of phase I thrombolysis in myocardial infarction (TIMI) trial. The TIMI Investigators. Circulation 1991;83:739–46.
  • 15. Werner GS, Ferrari M, Heinke S, Kuethe F, Surber R, Richartz BM, et al. Angiographic assessment of collateral connections in comparison with invasively determined collateral function in chronic coronary occlusions. Circulation 2003; 107:1972–7.
  • 16. Imhof BA, Aurrand-Lions M. Angiogenesis and inflammation face off. Nat Med 2006;12:171–2.
  • 17. Pekdemir H, Polat G, Cin VG, Camsari A, Cicek D, Akkus MN, et al. Elevated plasma endothelin-1 levels in coronary sinus during rapid right atrial pacing in patients with slow coronary flow. Int J Cardiol 2004;97:35–41.
  • 18. Gok M, Kundi H, Kiziltunc E, Topcuoglu C, Ornek E. Endocan Levels and Coronary Collateral Circulation in Stable Angina Pectoris: A Pilot Study. Angiology 2018;69:43–8.
  • 19. Açar G, Kalkan ME, Avci A, Alizade E, Tabakci MM, Toprak C, et al. The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris and chronic total occlusion. Clin Appl Thromb Hemost 2015;21:462–8.
  • 20. Kurtul A, Yarlioglues M, Murat SN, Ergun G, Duran M, Kasapkara HA, et al. Usefulness of the platelet-to-lymphocyte ratio in predicting angiographic reflow after primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction. Am J Cardiol 2014;114:342–7.
  • 21. Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med 2003;348:138–50.
  • 22. Duffy BK, Gurm HS, Rajagopal V, Gupta R, Ellis SG, Bhatt DL. Usefulness of an elevated neutrophil to lymphocyte ratio in predicting longterm mortality after percutaneous coronary intervention. Am J Cardiol 2006;97:993–6.
  • 23. Kayacan O, Karnak D, Beder S, Güllü E, Tutkak H, Senler FC, et al. Impact of TNF-alpha and IL-6 levels on development of cachexia in newly diagnosed NSCLC patients. Am J Clin Oncol 2006;29:328–35.
  • 24. Kaushansky K. Growth factors and hematopoietic cell fate. A new feature: controversies in hematology. Blood 1998;92:345–4.
  • 25. Takeuchi H, Abe M, Takumi Y, Hashimoto T, Kobayashi R, Osoegawa A, et al. The prognostic impact of the platelet distribution width-to-platelet count ratio in patients with breast cancer. PLoS One 2017;12:e0189166.
  • 26. Aydogan A, Akkucuk S, Arica S, Motor S, Karakus A, Ozkan OV, et al. The Analysis of Mean Platelet Volume and Platelet Distribution Width Levels in Appendicitis. Indian J Surg 2015;77:495–500.
  • 27. Dinc B, Oskay A, Dinc SE, Bas B, Tekin S. New parameter in diagnosis of acute appendicitis: platelet distribution width. World J Gastroenterol 2015;21:1821–6.
  • 28. Orak M, Karakoç Y, Ustundag M, Yildirim Y, Celen MK, Güloglu C. An investigation of the effects of the mean platelet volume, platelet distribution width, platelet/lymphocyte ratio, and platelet counts on mortality in patents with sepsis who applied to the emergency department. Niger J Clin Pract 2018;21:667–71.
  • 29. Guo F, Zhu X, Qin X. Platelet Distribution Width in Hepatocellular Carcinoma. Med Sci Monit 2018;24:2518–23.
  • 30. Liu J, Liu X, Li Y, Quan J, Wei S, An S, et al. The association of neutrophil to lymphocyte ratio, mean platelet volume, and platelet distribution width with diabetic retinopathy and nephropathy: a meta-analysis. Biosci Rep 2018;38:BSR20180172.
  • 31. Ozyurtlu F, Yavuz V, Cetin N, Acet H, Ayhan E, Isik T. The association between coronary slow flow and platelet distribution width among patients with stable angina pectoris. Postepy Kardiol Interwencyjnej 2014;10:161–5.
APA sincer i, Kurtar Mansıroğlu A, Erdal E, COSGUN M, Aktas G, gunes y (2020). Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. , 112 - 117. 10.14744/nci.2019.47374
Chicago sincer isa,Kurtar Mansıroğlu Aslı,Erdal Emrah,COSGUN MEHMET,Aktas Gulali,gunes yilmaz Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. (2020): 112 - 117. 10.14744/nci.2019.47374
MLA sincer isa,Kurtar Mansıroğlu Aslı,Erdal Emrah,COSGUN MEHMET,Aktas Gulali,gunes yilmaz Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. , 2020, ss.112 - 117. 10.14744/nci.2019.47374
AMA sincer i,Kurtar Mansıroğlu A,Erdal E,COSGUN M,Aktas G,gunes y Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. . 2020; 112 - 117. 10.14744/nci.2019.47374
Vancouver sincer i,Kurtar Mansıroğlu A,Erdal E,COSGUN M,Aktas G,gunes y Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. . 2020; 112 - 117. 10.14744/nci.2019.47374
IEEE sincer i,Kurtar Mansıroğlu A,Erdal E,COSGUN M,Aktas G,gunes y "Could platelet distribution width predict coronary collateral development in stable coronary artery disease?." , ss.112 - 117, 2020. 10.14744/nci.2019.47374
ISNAD sincer, isa vd. "Could platelet distribution width predict coronary collateral development in stable coronary artery disease?". (2020), 112-117. https://doi.org/10.14744/nci.2019.47374
APA sincer i, Kurtar Mansıroğlu A, Erdal E, COSGUN M, Aktas G, gunes y (2020). Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. İstanbul Kuzey Klinikleri, 7(2), 112 - 117. 10.14744/nci.2019.47374
Chicago sincer isa,Kurtar Mansıroğlu Aslı,Erdal Emrah,COSGUN MEHMET,Aktas Gulali,gunes yilmaz Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. İstanbul Kuzey Klinikleri 7, no.2 (2020): 112 - 117. 10.14744/nci.2019.47374
MLA sincer isa,Kurtar Mansıroğlu Aslı,Erdal Emrah,COSGUN MEHMET,Aktas Gulali,gunes yilmaz Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. İstanbul Kuzey Klinikleri, vol.7, no.2, 2020, ss.112 - 117. 10.14744/nci.2019.47374
AMA sincer i,Kurtar Mansıroğlu A,Erdal E,COSGUN M,Aktas G,gunes y Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. İstanbul Kuzey Klinikleri. 2020; 7(2): 112 - 117. 10.14744/nci.2019.47374
Vancouver sincer i,Kurtar Mansıroğlu A,Erdal E,COSGUN M,Aktas G,gunes y Could platelet distribution width predict coronary collateral development in stable coronary artery disease?. İstanbul Kuzey Klinikleri. 2020; 7(2): 112 - 117. 10.14744/nci.2019.47374
IEEE sincer i,Kurtar Mansıroğlu A,Erdal E,COSGUN M,Aktas G,gunes y "Could platelet distribution width predict coronary collateral development in stable coronary artery disease?." İstanbul Kuzey Klinikleri, 7, ss.112 - 117, 2020. 10.14744/nci.2019.47374
ISNAD sincer, isa vd. "Could platelet distribution width predict coronary collateral development in stable coronary artery disease?". İstanbul Kuzey Klinikleri 7/2 (2020), 112-117. https://doi.org/10.14744/nci.2019.47374