Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study
Yıl: 2020 Cilt: 50 Sayı: 4 Sayfa Aralığı: 1097 - 1105 Metin Dili: İngilizce DOI: 10.3906/sag-2002-179 İndeks Tarihi: 31-08-2020
Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study
Öz: Background and aim: To compare the effects of bilateral proximal tubal occlusion and bilateral total salpingectomy on ovarian reserveand the cholinergic system via rat experiment.Materials and methods: Twenty-one adult female rats were randomly divided into the following three groups: G1 (n = 7), sham group;G2 (n = 7), bilateral total salpingectomy group; and G3 (n = 7), bilateral proximal tubal occlusion group. Four weeks later, the abdomenof the rats was opened. The right ovarian tissues were stored in 10% formaldehyde, whereas the left ovarian tissues were stored at–80 °C in aluminum foil. Serum samples were evaluated for antimullerian hormone. The right ovary was used for histological andimmunoreactive examination, and the left ovary was used for tissue MDA analysis. Tissue samples were analyzed for MDA levels withspectrophotometric measurement, apoptosis with TUNEL staining, fibrosis score with Mason trichrome staining, ovarian reserve withHE staining, and cholinergic receptor muscarinic 1 (CHRM1) level with immunoreactivity method.Results: Compared to G1 and G3, the number of corpus luteum with secondary follicles was significantly lower in G2, whereas thenumber of ovarian cysts and fibrosis and apoptosis scores increased significantly. The CHRM1 immunoreactivity was significantly lowerin G2 than in G1 and G3.Conclusions: Compared to the bilateral proximal tubal occlusion performed by using bipolar cautery, bilateral total salpingectomy inrats leads to a significant damage in ovarian histopathology and the cholinergic system.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Atilgan R, Pala Ş, KULOĞLU T, şanlı c, Yavuzkır Ş, OZKAN Z (2020). Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. , 1097 - 1105. 10.3906/sag-2002-179 |
| Chicago | Atilgan Remzi,Pala Şehmus,KULOĞLU TUNCAY,şanlı cengiz,Yavuzkır Şeyda,OZKAN ZEHRA SEMA Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. (2020): 1097 - 1105. 10.3906/sag-2002-179 |
| MLA | Atilgan Remzi,Pala Şehmus,KULOĞLU TUNCAY,şanlı cengiz,Yavuzkır Şeyda,OZKAN ZEHRA SEMA Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. , 2020, ss.1097 - 1105. 10.3906/sag-2002-179 |
| AMA | Atilgan R,Pala Ş,KULOĞLU T,şanlı c,Yavuzkır Ş,OZKAN Z Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. . 2020; 1097 - 1105. 10.3906/sag-2002-179 |
| Vancouver | Atilgan R,Pala Ş,KULOĞLU T,şanlı c,Yavuzkır Ş,OZKAN Z Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. . 2020; 1097 - 1105. 10.3906/sag-2002-179 |
| IEEE | Atilgan R,Pala Ş,KULOĞLU T,şanlı c,Yavuzkır Ş,OZKAN Z "Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study." , ss.1097 - 1105, 2020. 10.3906/sag-2002-179 |
| ISNAD | Atilgan, Remzi vd. "Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study". (2020), 1097-1105. https://doi.org/10.3906/sag-2002-179 |
| APA | Atilgan R, Pala Ş, KULOĞLU T, şanlı c, Yavuzkır Ş, OZKAN Z (2020). Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. Turkish Journal of Medical Sciences, 50(4), 1097 - 1105. 10.3906/sag-2002-179 |
| Chicago | Atilgan Remzi,Pala Şehmus,KULOĞLU TUNCAY,şanlı cengiz,Yavuzkır Şeyda,OZKAN ZEHRA SEMA Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. Turkish Journal of Medical Sciences 50, no.4 (2020): 1097 - 1105. 10.3906/sag-2002-179 |
| MLA | Atilgan Remzi,Pala Şehmus,KULOĞLU TUNCAY,şanlı cengiz,Yavuzkır Şeyda,OZKAN ZEHRA SEMA Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. Turkish Journal of Medical Sciences, vol.50, no.4, 2020, ss.1097 - 1105. 10.3906/sag-2002-179 |
| AMA | Atilgan R,Pala Ş,KULOĞLU T,şanlı c,Yavuzkır Ş,OZKAN Z Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. Turkish Journal of Medical Sciences. 2020; 50(4): 1097 - 1105. 10.3906/sag-2002-179 |
| Vancouver | Atilgan R,Pala Ş,KULOĞLU T,şanlı c,Yavuzkır Ş,OZKAN Z Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. Turkish Journal of Medical Sciences. 2020; 50(4): 1097 - 1105. 10.3906/sag-2002-179 |
| IEEE | Atilgan R,Pala Ş,KULOĞLU T,şanlı c,Yavuzkır Ş,OZKAN Z "Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study." Turkish Journal of Medical Sciences, 50, ss.1097 - 1105, 2020. 10.3906/sag-2002-179 |
| ISNAD | Atilgan, Remzi vd. "Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study". Turkish Journal of Medical Sciences 50/4 (2020), 1097-1105. https://doi.org/10.3906/sag-2002-179 |
