Nanotoxicity: a challenge for future medicine

Aydogan, Halit Canberk; TAŞTEKİN, Burak; Akcan, Ramazan; SAGLAM, NECDET; Yıldırım, Mahmut Şerif

doi:10.3906/sag-1912-209

Nanotoxicity: a challenge for future medicine

Ramazan AKÇAN, (Hacettepe Üniversitesi, Tıp Fakültesi, Adli Tıp Anabilim Dalı, Ankara, Türkiye)

Halit AYDOGAN, (Hacettepe Üniversitesi, Tıp Fakültesi, Adli Tıp Anabilim Dalı, Ankara, Türkiye)

Mahmut Şerif YILDIRIM, (Afyonkarahisar Sağlık Bilimleri Üniversitesi, Tıp Fakültesi, Adli Tıp Anabilim Dalı, Afyonkarahisar, Türkiye)

Burak TAŞTEKİN, (Hacettepe Üniversitesi, Tıp Fakültesi, Adli Tıp Anabilim Dalı, Ankara, Türkiye)

Necdet SAGLAM (Hacettepe Üniversitesi, Fen Bilimleri Enstitüsü, Nanoteknoloji ve Nanotıp Bölümü, Ankara, Türkiye)

Turkish Journal of Medical Sciences

5 0

Yıl: 2020 Cilt: 50 Sayı: 4 Sayfa Aralığı: 1180 - 1196 Metin Dili: İngilizce DOI: 10.3906/sag-1912-209 İndeks Tarihi: 31-08-2020

Nanotoxicity: a challenge for future medicine

Öz:

Background/aim: Due to nanomaterials’ potential benefits for diagnosis and treatment, they are widely used in medical applicationsand personal care products. Interaction of nanomaterials, which are very small in size, with tissue, cell and microenvironment, canreveal harmful effects that cannot be created with chemically identical and larger counterparts in biological organisms. In this review, achallenge for future medicine, nanotoxicity of nanomaterials is discussed.Materials and methods: A detailed review of related literature was performed and evaluated as per medical applications of nanomaterialstheir toxicity.Results and conclusion: Most authors state “the only valid technology will be nanotechnology in the next era”; however, there is noconsensus on the impact of this technology on humankind, environment and ecological balance. Studies dealing with the toxic effect ofnanomaterials on human health have also varied with developing technology. Nanotoxicology studies such as in vivo-like on 3D humanorgans, cells, advanced genetic studies, and -omic approaches begin to replace conventional methods. Nanotoxicity and adverse effectsof nanomaterials in exposed producers, industry workers, and patients make nanomaterials a double-edged sword for future medicine.In order to control and tackle related risks, regulation and legislations should be implemented, and researchers have to conduct jointmultidisciplinary studies in various fields of medical sciences, nanotechnology, nanomedicine, and biomedical engineering.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	Akcan R, Aydogan H, Yıldırım M, TAŞTEKİN B, SAGLAM N (2020). Nanotoxicity: a challenge for future medicine. , 1180 - 1196. 10.3906/sag-1912-209
Chicago	Akcan Ramazan,Aydogan Halit Canberk,Yıldırım Mahmut Şerif,TAŞTEKİN Burak,SAGLAM NECDET Nanotoxicity: a challenge for future medicine. (2020): 1180 - 1196. 10.3906/sag-1912-209
MLA	Akcan Ramazan,Aydogan Halit Canberk,Yıldırım Mahmut Şerif,TAŞTEKİN Burak,SAGLAM NECDET Nanotoxicity: a challenge for future medicine. , 2020, ss.1180 - 1196. 10.3906/sag-1912-209
AMA	Akcan R,Aydogan H,Yıldırım M,TAŞTEKİN B,SAGLAM N Nanotoxicity: a challenge for future medicine. . 2020; 1180 - 1196. 10.3906/sag-1912-209
Vancouver	Akcan R,Aydogan H,Yıldırım M,TAŞTEKİN B,SAGLAM N Nanotoxicity: a challenge for future medicine. . 2020; 1180 - 1196. 10.3906/sag-1912-209
IEEE	Akcan R,Aydogan H,Yıldırım M,TAŞTEKİN B,SAGLAM N "Nanotoxicity: a challenge for future medicine." , ss.1180 - 1196, 2020. 10.3906/sag-1912-209
ISNAD	Akcan, Ramazan vd. "Nanotoxicity: a challenge for future medicine". (2020), 1180-1196. https://doi.org/10.3906/sag-1912-209

APA	Akcan R, Aydogan H, Yıldırım M, TAŞTEKİN B, SAGLAM N (2020). Nanotoxicity: a challenge for future medicine. Turkish Journal of Medical Sciences, 50(4), 1180 - 1196. 10.3906/sag-1912-209
Chicago	Akcan Ramazan,Aydogan Halit Canberk,Yıldırım Mahmut Şerif,TAŞTEKİN Burak,SAGLAM NECDET Nanotoxicity: a challenge for future medicine. Turkish Journal of Medical Sciences 50, no.4 (2020): 1180 - 1196. 10.3906/sag-1912-209
MLA	Akcan Ramazan,Aydogan Halit Canberk,Yıldırım Mahmut Şerif,TAŞTEKİN Burak,SAGLAM NECDET Nanotoxicity: a challenge for future medicine. Turkish Journal of Medical Sciences, vol.50, no.4, 2020, ss.1180 - 1196. 10.3906/sag-1912-209
AMA	Akcan R,Aydogan H,Yıldırım M,TAŞTEKİN B,SAGLAM N Nanotoxicity: a challenge for future medicine. Turkish Journal of Medical Sciences. 2020; 50(4): 1180 - 1196. 10.3906/sag-1912-209
Vancouver	Akcan R,Aydogan H,Yıldırım M,TAŞTEKİN B,SAGLAM N Nanotoxicity: a challenge for future medicine. Turkish Journal of Medical Sciences. 2020; 50(4): 1180 - 1196. 10.3906/sag-1912-209
IEEE	Akcan R,Aydogan H,Yıldırım M,TAŞTEKİN B,SAGLAM N "Nanotoxicity: a challenge for future medicine." Turkish Journal of Medical Sciences, 50, ss.1180 - 1196, 2020. 10.3906/sag-1912-209
ISNAD	Akcan, Ramazan vd. "Nanotoxicity: a challenge for future medicine". Turkish Journal of Medical Sciences 50/4 (2020), 1180-1196. https://doi.org/10.3906/sag-1912-209