The assessment of skin sebum and moisture content of infants with atopic dermatitis
Yıl: 2020 Cilt: 50 Sayı: 4 Sayfa Aralığı: 844 - 848 Metin Dili: İngilizce DOI: 10.3906/sag-1912-56 İndeks Tarihi: 28-08-2020
The assessment of skin sebum and moisture content of infants with atopic dermatitis
Öz: Background/aim: Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by dry skin, pruritus and eczematouslesions. The aim of this study is to evaluate the skin moisture and sebum content of the infants with AD and its relationship between thedisease severity.Materials and methods: For this cross-sectional and case-control study we included 49 infants with AD aged between 2 and 24 monthsand 34 healthy infants with the same age and sex as a control group. Skin moisture and sebum content were measured by the bioimpedance method and recorded. Skin prick tests, total IgE levels and food-specific (milk, egg) IgE levels were performed.Results: There was a significant difference between the groups in terms of mean skin moisture and sebum content percentage (P < 0.001,both). The mean skin moisture and sebum content were correlated with CRP in patients with AD (P < 0.01, r = –1.00, both), but we didnot find any correlation between these parameters with the disease severity.Conclusion: We found that skin moisture and sebum content were low even in unaffected areas in AD. The skin structure of thesepatients may contribute to the pathogenesis of the disease.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Gupta J, Grube E, Ericksen MB, Stevenson MD, Lucky AW et al. Intrinsically defective skin barrier function in Children with atopic dermatitis correlates with disease severity. The Journal Allergy and Clinical Immunology 2008; 121 (3): 725-730.e2. doi:10.1016/j.jaci.2007.12.1161. Epub 2008 Feb 4.
- 2. Martinsen ØG, Grimnes S, Kirkhus T, Mørkrid L, Aas K. Increased moisture content in children’s atopic skin. European Journal of Pediatric Dermatolology 2007; 17: 17-20.
- 3. Lodén M, Olsson H, Axéll T, Linde YW. Friction, capacitance and transepidermal water loss (TEWL) in dry atopic and normal skin. The British Journal of Dermatology 1992; 126 (2): 137-141. doi: 10.1111/j.1365-2133.1992.tb07810.x
- 4. Sator PG, Schmidt JB, Hönigsmann H. Comparison of epidermal hydration and skin surface lipids in healthy individuals and in patients with atopic dermatitis. Journal of American Academy of Dermatology 2003; 48 (3):352-358. doi: 10.1067/mjd.2003.105
- 5. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermato-venereologica Suppl 1980; 92: 44-47.
- 6. Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology 1993; 186: 23-31. doi: 10.1159/000247298
- 7. Tupker RA, Pinnagoda J, Coenraads PJ, Nater JP. Susceptibility to irritants: role of barrier function, skin dryness and history of atopic dermatitis. The British Journal of Dermatology 1990; 123: 199-205. doi: 10.1111/j.1365-2133.1990.tb01847.x
- 8. Werner Y. The water content of the stratum corneum in patients with atopic dermatitis. Measurement with the Corneometer CM 420. Acta Dermato-venereologica 1986; 66: 281-284.
- 9. Gloor M, Heymann B, Stuhlert T. Infrared-spectroscopic determination of the water content of the horny layer in healthy subjects and in patients suffering from atopic dermatitis. Archives of Dermatological Research 1981; 271: 429-436. doi: 10.1007/bf00406688
- 10. Finlay AY, Nicholls S, King CS, Marks R. The “dry’ noneczematous skin associated with atopic eczema.The British Journal of Dermatology 1980; 102: 249-256. doi: 10.1111/ j.1365-2133.1980.tb07241.x
- 11. GürÇetinkaya P, Şahiner ÜM. Childhood atopic dermatitis: current developments, treatment approaches, and future expectations. Turkish Journal of Medical Sciences 2019; 49 (4): 963-984. doi: 10.3906/sag-1810-105
- 12. Jiang Y, Ma W. Assessment of neutrophil-to-lymphocyte ratio and platelet-tolymphocyte ratio in atopic dermatitis patients. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2017; 17 (23): 1340-1346. doi: 10.12659/ msm.900212
- 13. Tang TS, Bieber T, Williams HC. Are the concepts of induction of remission and treatment of subclinical inflammation in atopic dermatitis clinically useful? The Journal of Allergy and Clinical Immunology 2014; 133: 1615-1625.e1. doi: 10.1016/j. jaci.2013.12.1079
- 14. Mu Z, Zhao Y, Liu X, Chang C, Zhang J. Molecular biology of atopic dermatitis. Clinical Reviews in Allergy & Immunology 2014; 47: 193-218. doi: 10.1007/s12016-014-8415-1
- 15. Vekaria AS, Brunner PM, Aleisa AI, Bonomo L, Lebwohl MG et al. Moderate-to-severe atopic dermatitis patients show increases in serum C-reactive protein levels, correlating with skin disease activity. Version 2. F1000Res. 2017; 6: 1712. doi: 10.12688/f1000research.12422.2
- 16. Akdis CA, Akdis M, Bieber T, Bindslev-Jensen C, Boguniewicz M et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. Allergy 2006; 61 (8): 969-87.
| APA | güneş h, NAZİK H, ÖZKARS M, parlak n, Yildiz A, Duyuran Ö, Yalçın B (2020). The assessment of skin sebum and moisture content of infants with atopic dermatitis. , 844 - 848. 10.3906/sag-1912-56 |
| Chicago | güneş hatice,NAZİK Hülya,ÖZKARS Mehmet Yaşar,parlak nurgül,Yildiz Ayten,Duyuran Ömer,Yalçın Bahaüddin Ahmed The assessment of skin sebum and moisture content of infants with atopic dermatitis. (2020): 844 - 848. 10.3906/sag-1912-56 |
| MLA | güneş hatice,NAZİK Hülya,ÖZKARS Mehmet Yaşar,parlak nurgül,Yildiz Ayten,Duyuran Ömer,Yalçın Bahaüddin Ahmed The assessment of skin sebum and moisture content of infants with atopic dermatitis. , 2020, ss.844 - 848. 10.3906/sag-1912-56 |
| AMA | güneş h,NAZİK H,ÖZKARS M,parlak n,Yildiz A,Duyuran Ö,Yalçın B The assessment of skin sebum and moisture content of infants with atopic dermatitis. . 2020; 844 - 848. 10.3906/sag-1912-56 |
| Vancouver | güneş h,NAZİK H,ÖZKARS M,parlak n,Yildiz A,Duyuran Ö,Yalçın B The assessment of skin sebum and moisture content of infants with atopic dermatitis. . 2020; 844 - 848. 10.3906/sag-1912-56 |
| IEEE | güneş h,NAZİK H,ÖZKARS M,parlak n,Yildiz A,Duyuran Ö,Yalçın B "The assessment of skin sebum and moisture content of infants with atopic dermatitis." , ss.844 - 848, 2020. 10.3906/sag-1912-56 |
| ISNAD | güneş, hatice vd. "The assessment of skin sebum and moisture content of infants with atopic dermatitis". (2020), 844-848. https://doi.org/10.3906/sag-1912-56 |
| APA | güneş h, NAZİK H, ÖZKARS M, parlak n, Yildiz A, Duyuran Ö, Yalçın B (2020). The assessment of skin sebum and moisture content of infants with atopic dermatitis. Turkish Journal of Medical Sciences, 50(4), 844 - 848. 10.3906/sag-1912-56 |
| Chicago | güneş hatice,NAZİK Hülya,ÖZKARS Mehmet Yaşar,parlak nurgül,Yildiz Ayten,Duyuran Ömer,Yalçın Bahaüddin Ahmed The assessment of skin sebum and moisture content of infants with atopic dermatitis. Turkish Journal of Medical Sciences 50, no.4 (2020): 844 - 848. 10.3906/sag-1912-56 |
| MLA | güneş hatice,NAZİK Hülya,ÖZKARS Mehmet Yaşar,parlak nurgül,Yildiz Ayten,Duyuran Ömer,Yalçın Bahaüddin Ahmed The assessment of skin sebum and moisture content of infants with atopic dermatitis. Turkish Journal of Medical Sciences, vol.50, no.4, 2020, ss.844 - 848. 10.3906/sag-1912-56 |
| AMA | güneş h,NAZİK H,ÖZKARS M,parlak n,Yildiz A,Duyuran Ö,Yalçın B The assessment of skin sebum and moisture content of infants with atopic dermatitis. Turkish Journal of Medical Sciences. 2020; 50(4): 844 - 848. 10.3906/sag-1912-56 |
| Vancouver | güneş h,NAZİK H,ÖZKARS M,parlak n,Yildiz A,Duyuran Ö,Yalçın B The assessment of skin sebum and moisture content of infants with atopic dermatitis. Turkish Journal of Medical Sciences. 2020; 50(4): 844 - 848. 10.3906/sag-1912-56 |
| IEEE | güneş h,NAZİK H,ÖZKARS M,parlak n,Yildiz A,Duyuran Ö,Yalçın B "The assessment of skin sebum and moisture content of infants with atopic dermatitis." Turkish Journal of Medical Sciences, 50, ss.844 - 848, 2020. 10.3906/sag-1912-56 |
| ISNAD | güneş, hatice vd. "The assessment of skin sebum and moisture content of infants with atopic dermatitis". Turkish Journal of Medical Sciences 50/4 (2020), 844-848. https://doi.org/10.3906/sag-1912-56 |
