Yıl: 2020 Cilt: 30 Sayı: 1 Sayfa Aralığı: 30 - 37 Metin Dili: İngilizce DOI: 10.5137/1019-5149.JTN.25776-19.2 İndeks Tarihi: 11-11-2020

The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms

Öz:
AIM: To investigate the safety and efficacy of Derivo® embolisation device (DED), a new-generation flow diverter designed to treatcerebrovascular aneurysms, and its long-term clinical outcomes.MATERIAL and METHODS: In total, 146 patients with 182 aneurysms were treated with DED. The mean age of the participantswas 51.5 years; among them, 46 (31.5%) presented with acute subarachnoid haemorrhage. The mean aneurysm size was 8.3 mm,and 12 aneurysms were involved the vertebrobasilar system. Ophthalmic aneurysms account for most internal carotid artery (ICA)aneurysms.RESULTS: The Glasgow Coma Scale (GCS) score of 12 patients was <15. DED was associated with a mortality rate of 2.7% andpermanent morbidity rate of 3.4%, and a complete aneurysm occlusion rate was achieved in 78.7% of cases after 7.02 months.CONCLUSION: The DED device is a new-generation flow diverter with excellent opening behaviour and navigational benefits. Ourresults indicated a safe aneurysm occlusion with optimum morbidity and mortality values despite the fact that almost one-third ofthe patients presented with subarachnoid haemorrhage.KEYWORDS: Derivo® embolisation device, Cerebrovasc
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  • 1. Akgul E, Onan HB, Akpinar S, Balli HT, Aksungur EH: The DERIVO embolization device in the treatment of intracranial aneurysms: Short- and midterm results. World Neurosurgery 95:229-240, 2016
  • 2. Cagnazzo F, di Carlo DT, Cappucci M, Lefevre PH, Costalat V, Perrini P: Acutely ruptured intracranial aneurysms treated with flow-diverter stents: A systematic review and meta-analysis. AJNR Am J Neuroradiol 39(9):1669-1675, 2018
  • 3. Cognard C: Commentary on ‘Curative cerebrovascular reconstruction with the Pipeline embolization device: The emergence of definitive endovascular therapy for intracranial aneurysms. J Neurointerventional Surgery 10 Suppl 1:i8, 2018
  • 4. Colby GP, Bender MT, Lin LM, Beaty N, Caplan JM, Jiang B, Westbroek EM, Varjavand B, Campos JK, Huang J, Tamargo RJ, Coon AL: Declining complication rates with flow diversion of anterior circulation aneurysms after introduction of the pipeline flex: Analysis of a single-institution series of 568 cases. J Neurosurgery 12:1-7, 2018
  • 5. Fischer S, Aguilar-Pérez M, Henkes E, Kurre W, Ganslandt O, Bäzner H, Henkes H: Initial Experience with p64: A novel mechanically detachable flow diverter for the treatment of intracranial saccular sidewall aneurysms. Am J Neuroradiol 36:2082-2089, 2015
  • 6. Foa Torres G, Roca F, Noguera A, Godes J, Petrocelli S, Aznar I, Ales S, Muszynski P, Maehara R, Vicente M, Pumar JM: Silk flow-diverter stent for the treatment of complex intracranial aneurysms: A one-year follow-up multicenter study. Interv Neuroradiol 24:357-362, 2018
  • 7. Goertz L, Dorn F, Kraus B, Borggrefe J, Schlamann M, Forbrig R, Turowski B, Kabbasch C: Safety and efficacy of the derivo embolization device for the treatment of ruptured intracranial aneurysms. J Neurointerv Surg 11(3):290-295, 2019
  • 8. Gurkas E, Kaya T, Daglioglu E, Akmangit I, Belen D, Peker A, Dede D, Arat A: Silk device for the treatment of intracranial aneurysms. Part 1: Peri-procedural results, technical aspects and learning curve. Turkish Neurosurgery 26:525-532, 2016
  • 9. Kallmes DF, Brinjikji W, Cekirge S, Fiorella D, Hanel RA, Jabbour P, Lopes D, Lylyk P, McDougall CG, Siddiqui A: Safety and efficacy of the pipeline embolization device for treatment of intracranial aneurysms: A pooled analysis of 3 large studies. J Neurosurgery 127:775-780, 2017
  • 10. Kaya T, Daglioglu E, Gurkas E, Akmangit I, Peker A, Belen D, Dede D, Elhan AH, Arat A: Silk device for the treatment of intracranial aneurysms, part 2: Factors related to clinical and angiographic outcome. Turkish Neurosurgery 26:533-537, 2016
  • 11. Killer-Oberpfalzer M, Kocer N, Griessenauer CJ, Janssen H, Engelhorn T, Holtmannspötter M, Buhk JH, Finkenzeller T, Fesl G, Trenkler J, Reith W, Berlis A, Hausegger K, Augustin M, Islak C, Minnich B, Möhlenbruch M: European multicenter study for the evaluation of a dual-layer flow-diverting stent for treatment of wide-neck intracranial aneurysms: The European flow-redirection intraluminal device study. American J Neuroradiology 39:841-847, 2018
  • 12. Kraus B, Goertz L, Turowski B, Borggrefe J, Schlamann M, Dorn F, Kabbasch C: Safety and efficacy of the Derivo Embolization Device for the treatment of unruptured intracranial aneurysms: A multicentric study. J Neurointerv Surg 11(1):68-73, 2019
  • 13. Ley D, Mühl-Benninghaus R, Yilmaz U, Körner H, Cattaneo GFM, Mailänder W, Kim YJ, Scheller B, Reith W, Simgen A: The Derivo Embolization Device, a second-generation flow diverter for the treatment of intracranial aneurysms, evaluated in an elastase-induced aneurysm model. Clin Neuroradiol 27:335-343, 2017
  • 14. Liu JM, Zhou Y, Li Y, Li T, Leng B, Zhang P, Liang G, Huang Q, Yang PF, Shi H, Zhang J, Wan J, He W, Liang C, Zhu G, Xu Y, Hong B, Yang X, Bai W, Tian Y, Zhang H, Li Z, Li Q, Zhao R, Fang Y, Zhao K: Parent artery reconstruction for large or giant cerebral aneurysms using the tubridge flow diverter: A multicenter, randomized, controlled clinical trial (PARAT). Am J Neuroradiology 39:807-816, 2018
  • 15. Lozupone E, Piano M, Valvassori L, Quilici L, Pero G, Visconti E, Boccardi E: Flow diverter devices in ruptured intracranial aneurysms: A single-center experience. J Neurosurgery 128:1037-1043, 2018
  • 16. Lylyk P, Miranda C, Ceratto R, Ferrario A, Scrivano E, Luna HR, Berez AL, Tran Q, Nelson PK, Fiorella D: Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: The Buenos Aires experience. Neurosurgery 64:632-642,2009
  • 17. Morais R, Mine B, Bruyère PJ, Naeije G, Lubicz B: Endovascular treatment of intracranial aneurysms with the p64 flow diverter stent: Mid-term results in 35 patients with 41 intracranial aneurysms. Neuroradiology 59:263-269, 2017
  • 18. Pierot L, Spelle L, Berge J, Januel AC, Herbreteau D, Aggour M, Piotin M, Biondi A, Barreau X, Mounayer C, Papagiannaki C, Lejeune JP, Gauvrit JY, Costalat V: Feasibility, complications, morbidity, and mortality results at 6 months for aneurysm treatment with the Flow Re-Direction Endoluminal Device: Report of SAFE study. J Neurointerv Surg 10:765-770, 2018
  • 19. Pumar JM, Banguero A, Cuellar H, Guimaraens L, Masso J, Miralbes S, Blanco-Ulla M, Vazquez-Herrero F, Souto M, Gelabert-Gonzalez M: Treatment of intracranial aneurysms with the silk embolization device in a multicenter study. A retrospective data analysis. Neurosurgery 81:595-601, 2017
  • 20. Rajah G, Narayanan S, Rangel-Castilla L: Update on flow diverters for the endovascular management of cerebral aneurysms. Neurosurg Focus 42:E2, 2017
  • 21. Shankar JJ, Tampieri D, Iancu D, Cortes M, Agid R, Krings T, Wong J, Lavoie P, Ghostine J, Shettar B, Ritchie K, Weill A: SILK flow diverter for complex intracranial aneurysms: A Canadian registry. J Neurointerv Surg 8:273-278, 2016
  • 22. Wakhloo AK, Lylyk P, de Vries J, Taschner C, Lundquist J, Biondi A, Hartmann M, Szikora I, Pierot L, Sakai N, Imamura H, Sourour N, Rennie I, Skalej M, Beuing O, Bonafé A, Mery F, Turjman F, Brouwer P, Boccardi E, Valvassori L, Derakhshani S, Litzenberg MW, Gounis MJ: Surpass flow diverter in the treatment of intracranial aneurysms: A prospective multicenter study. American J Neuroradiology 36:98-107, 2015
  • 23. Zhou G, Su M, Yin YL, Li MH: Complications associated with the use of flow-diverting devices for cerebral aneurysms: A systematic review and meta-analysis. Neurosurg Focus 42(6):E17, 201
APA daglioglu e, AKMANGİT İ, acik v, Alagöz F, Sayın B, UCKUN O, BELEN A, ARAT A (2020). The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. , 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
Chicago daglioglu ergun,AKMANGİT İlkay,acik vedat,Alagöz Fatih,Sayın Bige,UCKUN Ozhan Merzuk,BELEN Ahmet Deniz,ARAT Anıl The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. (2020): 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
MLA daglioglu ergun,AKMANGİT İlkay,acik vedat,Alagöz Fatih,Sayın Bige,UCKUN Ozhan Merzuk,BELEN Ahmet Deniz,ARAT Anıl The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. , 2020, ss.30 - 37. 10.5137/1019-5149.JTN.25776-19.2
AMA daglioglu e,AKMANGİT İ,acik v,Alagöz F,Sayın B,UCKUN O,BELEN A,ARAT A The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. . 2020; 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
Vancouver daglioglu e,AKMANGİT İ,acik v,Alagöz F,Sayın B,UCKUN O,BELEN A,ARAT A The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. . 2020; 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
IEEE daglioglu e,AKMANGİT İ,acik v,Alagöz F,Sayın B,UCKUN O,BELEN A,ARAT A "The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms." , ss.30 - 37, 2020. 10.5137/1019-5149.JTN.25776-19.2
ISNAD daglioglu, ergun vd. "The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms". (2020), 30-37. https://doi.org/10.5137/1019-5149.JTN.25776-19.2
APA daglioglu e, AKMANGİT İ, acik v, Alagöz F, Sayın B, UCKUN O, BELEN A, ARAT A (2020). The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. Turkish Neurosurgery, 30(1), 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
Chicago daglioglu ergun,AKMANGİT İlkay,acik vedat,Alagöz Fatih,Sayın Bige,UCKUN Ozhan Merzuk,BELEN Ahmet Deniz,ARAT Anıl The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. Turkish Neurosurgery 30, no.1 (2020): 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
MLA daglioglu ergun,AKMANGİT İlkay,acik vedat,Alagöz Fatih,Sayın Bige,UCKUN Ozhan Merzuk,BELEN Ahmet Deniz,ARAT Anıl The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. Turkish Neurosurgery, vol.30, no.1, 2020, ss.30 - 37. 10.5137/1019-5149.JTN.25776-19.2
AMA daglioglu e,AKMANGİT İ,acik v,Alagöz F,Sayın B,UCKUN O,BELEN A,ARAT A The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. Turkish Neurosurgery. 2020; 30(1): 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
Vancouver daglioglu e,AKMANGİT İ,acik v,Alagöz F,Sayın B,UCKUN O,BELEN A,ARAT A The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms. Turkish Neurosurgery. 2020; 30(1): 30 - 37. 10.5137/1019-5149.JTN.25776-19.2
IEEE daglioglu e,AKMANGİT İ,acik v,Alagöz F,Sayın B,UCKUN O,BELEN A,ARAT A "The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms." Turkish Neurosurgery, 30, ss.30 - 37, 2020. 10.5137/1019-5149.JTN.25776-19.2
ISNAD daglioglu, ergun vd. "The Experience of the Derivo®Embolisation Device in Intracranial Aneurysms". Turkish Neurosurgery 30/1 (2020), 30-37. https://doi.org/10.5137/1019-5149.JTN.25776-19.2