Yıl: 2019 Cilt: 29 Sayı: 3 Sayfa Aralığı: 101 - 107 Metin Dili: İngilizce DOI: 10.5336/dermato.2019-70659 İndeks Tarihi: 23-09-2020

Do Patients with Psoriasis Suffer from Hearing Loss?

Öz:
Objective: Sensorineural hearing loss has been associated with various diseases includingvitiligo, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease and Behcet’sdisease in the etiopathogenesis of which autoimmunity and chronic inflammation play a role. However,limited studies are available evaluating hearing levels in psoriasis which is another chronic inflammatoryand autoimmune disease. The present study evaluates hearing levels in patients with psoriasis, achronic inflammatory disease which are often accompanied by other comorbid conditions, and makes acomparison with healthy controls. Material and Methods: Fifty psoriasis patients and 50 healthy volunteerswere included in the study. All participating patients underwent a complete otorhinolaryngologicexamination prior to undergoing audiometry. The patients underwent pure-tone audiometry in an audiometrylaboratory with voice isolation. Results: In the present study, statistically significant differenceswere noted between the groups in terms of hearing threshold in both left and right ear at 2000 Hz,and in the right ear at 4000 Hz and 8000 Hz. In all instances of significant difference, the patients in thepsoriasis group had higher values. The mean air- and bone-conduction hearing thresholds in the left andright ear were significantly higher in the psoriasis group (p<0.05). The correlation analysis which wasmade to identify any possible relationship between Psoriasis Area Severity Index (PASI) and duration ofdisease revealed no significant relationship or correlation. Conclusion: It should be kept in mind that hearingloss can occur in psoriasis patients, and they should be followed up regularly with audiometry.
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Öz:
Amaç: Sensörinöral işitme kaybı vitiligo, romatoid artrit, sistemik lupus eritematozus, inflamatuvar barsak hastalığı ve Behçet hastalığı gibi etyopatogenezinde otoimmünitenin ve kronik inflamasyonun rol oynadığı birçok hastalık ile ilişkilidir. Fakat psoriasis gibi kronik inflamatuar ve otoimmün bir hastalıkta işitme düzeyini değerlendiren kısıtlı sayıda çalışma vardır. Bu çalışma, pek çok komorbiditeler ile birlikte olabilen, kronik inflamatuar bir hastalık olan psoriasiste işitme düzeyini sağlıklı kontrol grubu ile karşılaştırmalı olarak değerlendirmektedir. Gereç ve Yöntemler: Çalışmaya 50 psöriyazis hastası ile 50 sağlıklı gönüllü dahil edildi. Çalışmaya katılan tüm hastalara işitme testi yapılmadan önce tam bir kulak, burun, boğaz muayenesi yapıldı. Ardından hastalara ses izolasyonu sağlanmış odyometri laboratuvarında saf ses odyometri değerlendirmesi yapıldı. Bulgular: Bu çalışmada 2000 Hz’de hem sol kulak hem de sağ kulak işitme eşiği değerleri yönünden, 4000 ve 8000 Hz’de sağ kulak işitme eşiği değerleri yönünden gruplar arasında istatistiksel olarak anlamlı bir fark olduğu bulunmuştur. Fark bulunan tüm durumlarda psöriyazis grubunun değerlerinin daha yüksek olduğu görülmüştür. Hava yolu ve kemik yolunda hem sol kulak hem de sağ kulak ortalama işitme değerleri yönünden psöriyazis grubunun değerlerinin istatistiksel olarak anlamlı şekilde yüksek olduğu saptanmıştır (p<0.05). Psöriyazis Alan Şiddet İndeksi (PASI) skoru ve hastalık süresiyle işitme kaybı arasında korelasyon analizinde anlamlı bir ilişki ve korelasyon olmadığı görülmüştür. Sonuç: Psöriyazis hastalarında işitme kaybı olabileceği akılda tutulmalı ve odyometri ile düzenli olarak izlenmelidir.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Rachakonda TD, Schupp CW, Armstrong AW. Psoriasis prevalence among adults in the United States. J Am Acad Dermatol. 2014;70(3):512-6. [Crossref] [PubMed]
  • 2. Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, et al. Psoriasis and comorbid diseases: epidemiology. J Am Acad Dermatol. 2017;76(3):377-90. [Crossref] [PubMed] [PMC]
  • 3. Gaspari AA. Innate and adaptive immunity and the pathophysiology of psoriasis. J Am Acad Dermatol. 2006;54(3 Suppl 2):S67-80. [Crossref] [PubMed]
  • 4. Boehncke WH, Boehncke S. More than skindeep: the many dimensions of the psoriatic disease. Swiss Med Wkly. 2014;144:w13968. [Crossref] [PubMed]
  • 5. Farley E, Menter A. Psoriasis: comorbidities and associations. G Ital Dermatol Venereol. 2011;146(1):9-15. [PubMed]
  • 6. Ni C, Chiu MW. Psoriasis and comorbidities: links and risks. Clin Cosmet Investig Dermatol. 2014;7:119-32. [Crossref] [PubMed] [PMC]
  • 7. McCabe BF. Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol. 1979;88(5 Pt 1):585-9. [Crossref] [PubMed]
  • 8. Fleissig E, Gross M, Ophir I, Elidan J, Bdolah- Abram T, Ingber A. Risk of sensorineural hearing loss in patients with vitiligo. Audiol Neurootol. 2013;18(4):240-6. [Crossref] [PubMed]
  • 9. Magaro M, Zoli A, Altomonte L, Mirone L, Corvino G, Di Girolamo S, et al. Sensorineural hearing loss in rheumatoid arthritis. Clin Exp Rheumatol. 1990;8(5):487-90. [PubMed]
  • 10. Andonopoulos AP, Naxakis S, Goumas P, Lygatsikas C. Sensorineural hearing disorders in systemic lupus erythematosus. A controlled study. Clin Exp Rheumatol. 1995;13(2):137- 41. [PubMed]
  • 11. Karmody CS, Valdez TA, Desai U, Blevins NH. Sensorineural hearing loss in patients with inflammatory bowel disease. Am J Otolaryngol. 2009;30(3):166-70. [Crossref] [PubMed]
  • 12. Sonbay ND, Saka C, Tatlican S, Vuralkan E, Aygener N, Eren C, et al. Audiological evaluation in patients with Behçet’s disease. J Laryngol Otol. 2014;128(8):694-7. [Crossref] [PubMed]
  • 13. Akdag M, Uçmak D, Özkurt FE, Bozkurt M, Akkurt ZM, Topçu İ. Evaluation of hearing and outer hair cell function of cochlea in patients with psoriatic arthritis. Clin Exp Otorhinolaryngol. 2015;8(3):183-8. [Crossref] [PubMed] [PMC]
  • 14. Karabulut H, Karadag AS, Dagli M, Acar B, Babademez MA, Sahin Y, et al. Investigation of hearing and outer hair cell function of cochlea in patients with psoriasis. Int Adv Otol. 2010;6(2):239-44.
  • 15. Alatas N, Yazgan P, Oztürk A, San I, Iynen I. Audiological findings in patients with ankylosing spondylitis. J Laryngol Otol. 2005;119(7):534-9. [Crossref] [PubMed]
  • 16. Berrocal JR, Ramírez-Camacho R. Sudden sensorineural hearing loss: supporting the immunologic theory. Ann Otol Rhinol Laryngol. 2002;111(11):989-97. [Crossref] [PubMed]
  • 17. Srikumar S, Deepak MK, Basu S, Kumar BN. Sensorineural hearing loss associated with psoriatic arthritis. J Laryngol Otol. 2004;118(11):909-11. [Crossref] [PubMed]
  • 18. Kumar BN, Walsh RM, Wilson PS, Carlin WV. Sensorineural hearing loss and ulcerative colitis. J Laryngol Otol. 1997;111(3):277-8. [Crossref] [PubMed]
  • 19. Güvenç SC, Turan H, Yılmaz S, Yanık ME, Berada A, Aliağaoğlu C. [Assesment of hearing loss in patients with psoriasis]. Türkderm. 2012;46:15-9. [Crossref]
  • 20. Yen YC, Lin YS, Weng SF, Lai FJ. Risk of sudden sensorineural hearing loss in patients with psoriasis: a retrospective cohort study. Am J Clin Dermatol. 2015;16(3):213-20. [Crossref] [PubMed]
  • 21. Borgia F, Ciodaro F, Guarneri F, Bartolotta A, Papaianni V, Guarneri C, et al. Auditory system involvement in psoriasis. Acta Derm Venereol. 2018;98(7):655-9. [Crossref] [PubMed]
  • 22. Langley RG, Ellis CN. Evaluating psoriasis with Psoriasis Area and Severity Index, Psoriasis Global Assessment, and Lattice System Physician's Global Assessment. J Am Acad Dermatol. 2004;51(4):563-9. [Crossref] [PubMed]
APA Gurel G, Kantekin Y, HABERAL CAN I (2019). Do Patients with Psoriasis Suffer from Hearing Loss?. , 101 - 107. 10.5336/dermato.2019-70659
Chicago Gurel Gulhan,Kantekin Yunus,HABERAL CAN ILKNUR Do Patients with Psoriasis Suffer from Hearing Loss?. (2019): 101 - 107. 10.5336/dermato.2019-70659
MLA Gurel Gulhan,Kantekin Yunus,HABERAL CAN ILKNUR Do Patients with Psoriasis Suffer from Hearing Loss?. , 2019, ss.101 - 107. 10.5336/dermato.2019-70659
AMA Gurel G,Kantekin Y,HABERAL CAN I Do Patients with Psoriasis Suffer from Hearing Loss?. . 2019; 101 - 107. 10.5336/dermato.2019-70659
Vancouver Gurel G,Kantekin Y,HABERAL CAN I Do Patients with Psoriasis Suffer from Hearing Loss?. . 2019; 101 - 107. 10.5336/dermato.2019-70659
IEEE Gurel G,Kantekin Y,HABERAL CAN I "Do Patients with Psoriasis Suffer from Hearing Loss?." , ss.101 - 107, 2019. 10.5336/dermato.2019-70659
ISNAD Gurel, Gulhan vd. "Do Patients with Psoriasis Suffer from Hearing Loss?". (2019), 101-107. https://doi.org/10.5336/dermato.2019-70659
APA Gurel G, Kantekin Y, HABERAL CAN I (2019). Do Patients with Psoriasis Suffer from Hearing Loss?. Türkiye Klinikleri Dermatoloji Dergisi, 29(3), 101 - 107. 10.5336/dermato.2019-70659
Chicago Gurel Gulhan,Kantekin Yunus,HABERAL CAN ILKNUR Do Patients with Psoriasis Suffer from Hearing Loss?. Türkiye Klinikleri Dermatoloji Dergisi 29, no.3 (2019): 101 - 107. 10.5336/dermato.2019-70659
MLA Gurel Gulhan,Kantekin Yunus,HABERAL CAN ILKNUR Do Patients with Psoriasis Suffer from Hearing Loss?. Türkiye Klinikleri Dermatoloji Dergisi, vol.29, no.3, 2019, ss.101 - 107. 10.5336/dermato.2019-70659
AMA Gurel G,Kantekin Y,HABERAL CAN I Do Patients with Psoriasis Suffer from Hearing Loss?. Türkiye Klinikleri Dermatoloji Dergisi. 2019; 29(3): 101 - 107. 10.5336/dermato.2019-70659
Vancouver Gurel G,Kantekin Y,HABERAL CAN I Do Patients with Psoriasis Suffer from Hearing Loss?. Türkiye Klinikleri Dermatoloji Dergisi. 2019; 29(3): 101 - 107. 10.5336/dermato.2019-70659
IEEE Gurel G,Kantekin Y,HABERAL CAN I "Do Patients with Psoriasis Suffer from Hearing Loss?." Türkiye Klinikleri Dermatoloji Dergisi, 29, ss.101 - 107, 2019. 10.5336/dermato.2019-70659
ISNAD Gurel, Gulhan vd. "Do Patients with Psoriasis Suffer from Hearing Loss?". Türkiye Klinikleri Dermatoloji Dergisi 29/3 (2019), 101-107. https://doi.org/10.5336/dermato.2019-70659