Objective: The test performance data of the commercial firm should be tested by evaluating the performance of the method before patient is given the result with a new method in medical laboratories. It has been aimed on this study that verification of tests which will work on the equipment of dry system biochemistry which is planned to be established to integrated hospital laboratories in trust of Bilecik Public Health Laboratory is made by EP15-A2 guideline which was published by Clinical and Laboratory Standards Institution (CLSI). Methods: Verification study has been made on Spotchem-EZ (Arkray) device on the base of CLSI, EP15-A2 guidelines for glucose, BUN, AST, ALT, TBIL, total cholesterol, and calcium tests. As a comparative device for the bias calculation, Mindray-BS800M device which is the current autoanalyzer was used. It was studied on Spotchem-EZ device in a way that there were to be 2 (two) level internal quality control as three times and repetitive for 5 (five) days, in order to calculate precision on above - designated tests. In order to calculate trueness, 20 patient serums were studied on SpotchemEZ and BS800M autoanalyzer. Verification values were calculated in company with EP15-A2 guidelines. Results: The within-run (Sr) precision value, verification limits are with inside for each two level of glucose, urea, total cholesterol, AST, and TBIL; for first level of ALT and calcium and also verification limits are outside for second levels of calcium and ALT. While the bias value is within the calculated verification limits for glucose, urea, total cholesterol, AST, ALT and TBIL; it is outside of verification limits for calcium. Conclusion: We consider that precision of parameters which were tested in company with EP15-A2 guideline and were studied by dry chemistry system are acceptable, conformity between tests which bias values are outside of verification limits and current autoanalyzer on laboratory is restricted and it will require that these parameters are to be verified by reference method.