Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia
Yıl: 2020 Cilt: 55 Sayı: 2 Sayfa Aralığı: 207 - 209 Metin Dili: İngilizce DOI: 10.14744/TurkPediatriArs.2019.12129 İndeks Tarihi: 19-08-2020
Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia
Öz: Invasive fungal infections may cause morbidity and mortality in pediatric patients with hematologic and oncologic malignancies treatedwith intensive protocols. We present a case of mucormycosis in an8-year-old boy with acute lymphoblastic leukemia. In our patient, thesuspicion for an oculoorbital and paranasal infection only due to mildpain in the orbital area without any abnormal pathologic findings inthe ophthalmologic and otolaryngologic examination, led us to an earlydiagnosis. Despite the use of antifungal therapy, the lesion persistedand fever subsided after surgical drainage of the periorbital abscess.Antifungal treatment continued during chemotherapy. He has been inremission for four years. Mucormycosis should be in the differentialdiagnosis in infections in children with cancer, especially leukemia, according to clinical and radiologic findings. A high degree of suspicionand prompt systemic empirical antifungal therapy, as well as surgicaldebridement, are crucial for the survival of patients. Beside antifungals,early surgery plays an important role in patients with mucormycosis.
Anahtar Kelime: Akut lenfoblastik lösemili bir çocuk hastada mukormikoz enfeksiyonunun başarılı tedavisi
Öz: Invaziv fungal enfeksiyonlar, yoğun tedaviler alan çocukluk çağı kanserlerinde mortalite ve morbiditenin önemli bir nedenidir. Bu yazıda, akut lenfoblastik lösemi tanılı sekiz yaşındaki erkek hastada saptanan mukormikoz enfeksiyonu irdelenmiştir. Ateş ve orbita etrafında hafif ağrı saptanan olgumuzda, kulak burun boğaz ve oftalmolojik değerlendirmede patolojik bulgu olmamasına rağmen, okuloorbital ve paranazal enfeksiyonun düşünülmesi, bizi erken tanıya götürdü. Görüntülemede saptanan periorbital apse, antifungal tedaviye ragmen gerilemedi ve cerrahi drenaj sonrasi ateş düştü. Kemoterapi boyunca antifungal tedavisine devam edilen hasta, tedavi bitiminden sonra dört yıldır hastalıksız izlenmektedir. Çocukluk çağı kanserlerinde, özellikle lösemi tanılı hastaların enfeksiyonlarda, klinik ve radyolojik bulgular dogrultusunda mukormikoz ayırıcı tanıda düşünülmelidir. Bu infeksiyonun ayırıcı tanıda düşünülmesi, hızla sistemik antifungal tedavi başlanması, ve cerrahi debridman hastaların hayatta kalmaları için çok önemlidir. Antifungal tedavi yanında, erken cerrahi drenaj, mukormikoz tedavisinde önemli rol oynar.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | KEBUDİ R, KIZILOCAK H, HAFIZ G, erturan z (2020). Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. , 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| Chicago | KEBUDİ Rejin,KIZILOCAK Hande,HAFIZ Günter,erturan zayre Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. (2020): 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| MLA | KEBUDİ Rejin,KIZILOCAK Hande,HAFIZ Günter,erturan zayre Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. , 2020, ss.207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| AMA | KEBUDİ R,KIZILOCAK H,HAFIZ G,erturan z Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. . 2020; 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| Vancouver | KEBUDİ R,KIZILOCAK H,HAFIZ G,erturan z Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. . 2020; 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| IEEE | KEBUDİ R,KIZILOCAK H,HAFIZ G,erturan z "Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia." , ss.207 - 209, 2020. 10.14744/TurkPediatriArs.2019.12129 |
| ISNAD | KEBUDİ, Rejin vd. "Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia". (2020), 207-209. https://doi.org/10.14744/TurkPediatriArs.2019.12129 |
| APA | KEBUDİ R, KIZILOCAK H, HAFIZ G, erturan z (2020). Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. Türk Pediatri Arşivi, 55(2), 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| Chicago | KEBUDİ Rejin,KIZILOCAK Hande,HAFIZ Günter,erturan zayre Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. Türk Pediatri Arşivi 55, no.2 (2020): 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| MLA | KEBUDİ Rejin,KIZILOCAK Hande,HAFIZ Günter,erturan zayre Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. Türk Pediatri Arşivi, vol.55, no.2, 2020, ss.207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| AMA | KEBUDİ R,KIZILOCAK H,HAFIZ G,erturan z Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. Türk Pediatri Arşivi. 2020; 55(2): 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| Vancouver | KEBUDİ R,KIZILOCAK H,HAFIZ G,erturan z Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia. Türk Pediatri Arşivi. 2020; 55(2): 207 - 209. 10.14744/TurkPediatriArs.2019.12129 |
| IEEE | KEBUDİ R,KIZILOCAK H,HAFIZ G,erturan z "Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia." Türk Pediatri Arşivi, 55, ss.207 - 209, 2020. 10.14744/TurkPediatriArs.2019.12129 |
| ISNAD | KEBUDİ, Rejin vd. "Successful outcome of mucormycosis in a child with acute lymphoblastic leukemia". Türk Pediatri Arşivi 55/2 (2020), 207-209. https://doi.org/10.14744/TurkPediatriArs.2019.12129 |
