Yıl: 2020 Cilt: 16 Sayı: 1 Sayfa Aralığı: 44 - 47 Metin Dili: İngilizce DOI: 10.5152/ejbh.2019.5068 İndeks Tarihi: 20-10-2020

Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases

Öz:
Objective: Adenoid cystic carcinoma (ACC) of the breast is an uncommon salivary type of breast carcinoma. It is a triple negative breast carcinomawith a basal-like phenotype that behaves in an indolent manner. Herein, we aimed to document clinicopathologic findings and hormone receptor statusof ACC in the breast diagnosed in our institution during an eleven-year period.Materials and Methods: Medical data of cases diagnosed as adenoid cystic carcinoma in the breast between January 2006 and December 2016 wereretrospectively reviewed from hospital data base. Paraffin blocks of seven cases were retrieved from the archive of Pathology Department and androgenreceptor (AR) immunohistochemistry was applied to each case.Results: All of the cases diagnosed as ACC were females with a mean age 56.2. Solid growth pattern was present in two cases. P63 was constantlyexpressed in the whole group, and at least one additional myoepithelial marker (calponin, caldesmon, etc.) was co-expressed in tumors. While weakestrogen receptor expression was detected only in one patient, AR was strikingly expressed in majority (%85.7) of the tumors.Conclusion: To our knowledge, our series is the first to report such high levels of AR expression. This new finding, in turn, suggests considering hormonaltherapy as an option in the management of ACC of the breast.
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APA Yigit S, Etit D, Şen L, Atahan M (2020). Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. , 44 - 47. 10.5152/ejbh.2019.5068
Chicago Yigit Seyran,Etit Demet,Şen Leyla,Atahan Murat Kemal Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. (2020): 44 - 47. 10.5152/ejbh.2019.5068
MLA Yigit Seyran,Etit Demet,Şen Leyla,Atahan Murat Kemal Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. , 2020, ss.44 - 47. 10.5152/ejbh.2019.5068
AMA Yigit S,Etit D,Şen L,Atahan M Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. . 2020; 44 - 47. 10.5152/ejbh.2019.5068
Vancouver Yigit S,Etit D,Şen L,Atahan M Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. . 2020; 44 - 47. 10.5152/ejbh.2019.5068
IEEE Yigit S,Etit D,Şen L,Atahan M "Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases." , ss.44 - 47, 2020. 10.5152/ejbh.2019.5068
ISNAD Yigit, Seyran vd. "Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases". (2020), 44-47. https://doi.org/10.5152/ejbh.2019.5068
APA Yigit S, Etit D, Şen L, Atahan M (2020). Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. European Journal of Breast Health, 16(1), 44 - 47. 10.5152/ejbh.2019.5068
Chicago Yigit Seyran,Etit Demet,Şen Leyla,Atahan Murat Kemal Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. European Journal of Breast Health 16, no.1 (2020): 44 - 47. 10.5152/ejbh.2019.5068
MLA Yigit Seyran,Etit Demet,Şen Leyla,Atahan Murat Kemal Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. European Journal of Breast Health, vol.16, no.1, 2020, ss.44 - 47. 10.5152/ejbh.2019.5068
AMA Yigit S,Etit D,Şen L,Atahan M Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. European Journal of Breast Health. 2020; 16(1): 44 - 47. 10.5152/ejbh.2019.5068
Vancouver Yigit S,Etit D,Şen L,Atahan M Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases. European Journal of Breast Health. 2020; 16(1): 44 - 47. 10.5152/ejbh.2019.5068
IEEE Yigit S,Etit D,Şen L,Atahan M "Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases." European Journal of Breast Health, 16, ss.44 - 47, 2020. 10.5152/ejbh.2019.5068
ISNAD Yigit, Seyran vd. "Androgen Receptor Expression in Adenoid Cystic Carcinoma of Breast: A Subset of Seven Cases". European Journal of Breast Health 16/1 (2020), 44-47. https://doi.org/10.5152/ejbh.2019.5068