Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort
Yıl: 2018 Cilt: 19 Sayı: 1 Sayfa Aralığı: 39 - 42 Metin Dili: İngilizce DOI: 10.5152/imj.2018.58751 İndeks Tarihi: 21-10-2020
Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort
Öz: Introduction: Chronic lymphocytic leukemia (CLL) is one of the most common leukemias in developed countries. Multiple myeloma (MM), a clonal plasma cell disease, is the second most prevalent hematological cancer. Interleukin-17 (IL-17) can facilitate the secretion of numerous proinflammatory cytokines. The goal of the present study was to evalu-ate the effect of IL-17F rs763780 on CLL/MM susceptibility in a Turkish cohort. Methods: The study included 37 patients with CLL, 21 patients with MM, and 100 healthy controls. The IL-17F rs763780 variant was genoty-ped using polymerase chain reaction-restriction fragment length poly-morphism (PCR-RFLP). The frequencies of the alleles and genotypes in patient and control groups were compared by the χ2 test. Results: No significant difference was found in the distribution of ge-notypes and alleles frequencies for IL-17F rs 763780 between the pati-ents and the healthy controls (P>0.05).Conclusion: Our results suggest that IL-17 rs763780 variant may not contribute to CLL and MM pathogenesis.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Nursal A, PEHLİVAN M, Kurnaz S, pehlivan s (2018). Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. , 39 - 42. 10.5152/imj.2018.58751 |
| Chicago | Nursal Ayse Feyda,PEHLİVAN MUSTAFA,Kurnaz Selin,pehlivan sacide Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. (2018): 39 - 42. 10.5152/imj.2018.58751 |
| MLA | Nursal Ayse Feyda,PEHLİVAN MUSTAFA,Kurnaz Selin,pehlivan sacide Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. , 2018, ss.39 - 42. 10.5152/imj.2018.58751 |
| AMA | Nursal A,PEHLİVAN M,Kurnaz S,pehlivan s Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. . 2018; 39 - 42. 10.5152/imj.2018.58751 |
| Vancouver | Nursal A,PEHLİVAN M,Kurnaz S,pehlivan s Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. . 2018; 39 - 42. 10.5152/imj.2018.58751 |
| IEEE | Nursal A,PEHLİVAN M,Kurnaz S,pehlivan s "Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort." , ss.39 - 42, 2018. 10.5152/imj.2018.58751 |
| ISNAD | Nursal, Ayse Feyda vd. "Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort". (2018), 39-42. https://doi.org/10.5152/imj.2018.58751 |
| APA | Nursal A, PEHLİVAN M, Kurnaz S, pehlivan s (2018). Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. İstanbul Medical Journal, 19(1), 39 - 42. 10.5152/imj.2018.58751 |
| Chicago | Nursal Ayse Feyda,PEHLİVAN MUSTAFA,Kurnaz Selin,pehlivan sacide Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. İstanbul Medical Journal 19, no.1 (2018): 39 - 42. 10.5152/imj.2018.58751 |
| MLA | Nursal Ayse Feyda,PEHLİVAN MUSTAFA,Kurnaz Selin,pehlivan sacide Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. İstanbul Medical Journal, vol.19, no.1, 2018, ss.39 - 42. 10.5152/imj.2018.58751 |
| AMA | Nursal A,PEHLİVAN M,Kurnaz S,pehlivan s Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. İstanbul Medical Journal. 2018; 19(1): 39 - 42. 10.5152/imj.2018.58751 |
| Vancouver | Nursal A,PEHLİVAN M,Kurnaz S,pehlivan s Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort. İstanbul Medical Journal. 2018; 19(1): 39 - 42. 10.5152/imj.2018.58751 |
| IEEE | Nursal A,PEHLİVAN M,Kurnaz S,pehlivan s "Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort." İstanbul Medical Journal, 19, ss.39 - 42, 2018. 10.5152/imj.2018.58751 |
| ISNAD | Nursal, Ayse Feyda vd. "Effect of the IL-17F rs763780 Variant on Chronic Lymphocytic Leukemia and Multiple Myeloma Risk in a Turkish Cohort". İstanbul Medical Journal 19/1 (2018), 39-42. https://doi.org/10.5152/imj.2018.58751 |
