Yıl: 2020 Cilt: 21 Sayı: 2 Sayfa Aralığı: 148 - 151 Metin Dili: İngilizce DOI: 10.4274/imj.galenos.2020.99907 İndeks Tarihi: 17-10-2020

A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer

Öz:
Approximately 50% of lung cancer patients have distantmetastases at diagnosis. Intestinal metastasis of lung canceris quite rare and mostly asymptomatic as well. A 65-yearoldmale patient had been referred to a peripheral hospitalwith the complaint of abdominal pain. A mass lesion locatedon the apex of the right lung had been detected; as well asbrain and abdominal metastases had been documented andoncotherapy had been planned accordingly. Several days later,he was referred to emergency surgery department due to thesymptoms of acute abdomen. Tests showed hollow organperforation, and the patient underwent operation later on.Perforation secondary to metastatic small intestine implantwas observed per-operatively and so, small bowel resectionwas performed accordingly. The pathology revealed metastaticadenocarcinoma of lung cancer. The prognosis of lung cancerpatients having bowel metastasis is poor with a low rate ofsurvival. In this study, we aimed to present a case of metastaticlung cancer patient who had Acute Abdomen syndrome due toperforation secondary to small bowel metastasis.
Anahtar Kelime:

Nadir Bir Akut Batın Sendromu Sebebi: Akciğer Kanserinin İnce Barsak Metastazına Sekonder Perforasyon

Öz:
Akciğer kanseri hastalarının yaklaşık %50’sinde tanı sırasında uzak metastazlar vardır. Akciğer kanserinin barsak metastazı oldukça nadirdir ve çoğunlukla asemptomatiktir. Altmış beş yaşında erkek hastanın karın ağrısı şikayeti ile başvurduğu periferik bir hastanede yapılan tetkiklerinde sağ akciğer apeksinde yer alan kitle lezyonu saptandı; beyin ve abdominal metastazları da bulunan hastaya onkolojik tedavi planlandı. Birkaç gün sonra, akut batın semptomları nedeniyle acil cerrahi birimine başvurdu. Yapılan tetkikler sonucu içi boş organ perforasyonu saptandı ve hasta ameliyata alındı. Operasyonda metastatik ince barsak implantına sekonder perforasyon görüldü ve bu nedenle ince barsak rezeksiyonu yapıldı. Patolojik değerlendirmesi, akciğer kanserinin metastatik adenokarsinomu olarak sonuçlandı. Barsak metastazı olan akciğer kanseri hastalarının prognozu kötü ve sağkalım oranı düşüktür. Bu çalışmada akciğer kanserinin ince barsak metastazına sekonder perforasyon nedeniyle Akut Batın sendromu gelişen bir hastayı sunmayı amaçladık.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
  • 1. Hsing CT, Kim HY, Lee JH, Han JS, Lee JH, Chang JS, et al. Gastrointestinal metastasis from a primary adenocarcinoma of the lung presenting with acute abdominal pain. Korean J Gastroenterol 2012; 59: 382–5.
  • 2. Akyildiz HY, Akcan AC, Sözüer E, Küçük C, Yilmaz N, Artiş T. Unusual causes of intestinal perforation and their surgical treatment. Ulus Travma Acil Cerrahi Derg 2009; 15: 579-83.
  • 3. Di JZ, Peng JY, Wang ZG. Prevalence, clinicopathological characteristics, treatment, and prognosis of intestinal metastasis of primary lung cancer: A comprehensive review. Surg Oncol 2014; 23: 72-80.
  • 4. McNeill PM, Wagman LD, Neifeld JP. Small bowel metastases from primary carcinoma of the lung. Cancer. 1987; 59: 1486-9.
  • 5. Berger A, Cellier C, Daniel C, Kron C, Riquet M, Barbier JP, et al. Small bowel metastases from primary carcinoma of the lung: clinical findings and outcome. Am J Gastroenterol1999; 94: 1884-7.
  • 6. Garwood RA, Sawyer MD, Ledesma EJ, Foley E, Claridge JA. A case and review of bowel perforation secondary to metastatic lung cancer. Am Surg 2005; 71: 110-6.
  • 7. Mao Y, Yang D, He J, Krasna MJ. Epidemiology of Lung Cancer. Surg Oncol Clin N Am 2016; 25: 439-45.
  • 8. Siegel RL, Miller KD, Jemal A. Cancer statistics 2017. CA Cancer J Clin. 2017; 67: 7-30.
  • 9. Pezzuto A, Mariotta S, Fioretti F, Uccini S. Metastasis to the colon from lung cancer presenting with severe hyponatremia and dyspnea in a young male: A case report and review of the literature. Oncol Lett 2013; 5: 1477-80.
  • 10. Jevremovic V, Abboud A, Krauss S. Colonic Metastasis with Anemia Leading to a Diagnosis of Primary Lung Adenocarcinoma. Case Rep Oncol Med 2016; 2016: 5275043.
  • 11. Bouzbib C, Chaput U, Jarrin I, Lavergne-Slove A, Marteau P, Dray X. “Bleeding from gastroduodenal metastases as the first manifestation of lung adenocarcinoma. Endoscopy 2014; 46 Suppl 1 UCTN: E474-5.
  • 12. Yang CJ, Hwang JJ, Kang WY, Chong IW, Wang TH, Sheu CC, et al. Gastrointestinal metastasis of primary lung carcinoma: clinical presentations and outcome. Lung Cancer J 2006; 54: 319-23.
  • 13. Pratto D, Resial M, Wulfson A, Gennaro M, Brarda M, Schmidt A. Jejunojejunal intussusception as presentation of a primary lung carcinoma: a case report. Acta Gastroenterol Latinoam 2012; 42: 50-2.
  • 14. Kaswala DH, Patel NR, Shah SS, Razack RM, Fitzhugh VA, Brelvi ZS. Metastatic lung adenocarcinoma mimicking a colonic polyp. N Am J Med Sci 2013; 5:3 06-7.
  • 15. Cedres S, Mulet-Margalef N, Montero MA, Martinez P, Martinez A, Felip E. Rectal metastases from squamous cell carcinoma: A case report and review of the literature. Case Rep Med 2012; 2012: 947524.
  • 16. Travis WD, Brambilla E, Nicholson AG, Yatabe Y, Austin JH, Beasley MB, et al. The 2015 World Health Organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification. J Thorac Oncol 2015; 10: 1243-60.
  • 17. Frank CD, Roy HD, Lynn T, Rogerio CL. DeVita, Hellman and Rosenberg’s Cancer: Principles & Practice of Oncology. 10th Edition. Wolters Kluwer Health Corp.; Philadelphia: 2015. Non-small Cell Lung Cancer; pp. 495-502.
  • 18. Işık A, Eken H, Demiryıldız I, Yılmaz I, Fırat D, Çimen O, et al. Rectum, Lymphoma, Adenocancer. Turk J Colorectal Dis 2015; 25: 106-8.
  • 19. Huang YM, Hsieh TY, Chen JR, Chien HP, Chang PH, Wang CH, et al. Gastric and colonic metastases from primary lung adenocarcinoma: A case report and review of the literature. Oncol Lett 2012; 4: 517-20.
APA Alizade E, ilhan M, Mollavelioğlu B, Sormaz İ, Eröz E, SÖNMEZ R (2020). A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. , 148 - 151. 10.4274/imj.galenos.2020.99907
Chicago Alizade Elchin,ilhan Mehmet,Mollavelioğlu Baran,Sormaz İsmail Cem,Eröz Erhan,SÖNMEZ RECEP ERÇİN A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. (2020): 148 - 151. 10.4274/imj.galenos.2020.99907
MLA Alizade Elchin,ilhan Mehmet,Mollavelioğlu Baran,Sormaz İsmail Cem,Eröz Erhan,SÖNMEZ RECEP ERÇİN A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. , 2020, ss.148 - 151. 10.4274/imj.galenos.2020.99907
AMA Alizade E,ilhan M,Mollavelioğlu B,Sormaz İ,Eröz E,SÖNMEZ R A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. . 2020; 148 - 151. 10.4274/imj.galenos.2020.99907
Vancouver Alizade E,ilhan M,Mollavelioğlu B,Sormaz İ,Eröz E,SÖNMEZ R A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. . 2020; 148 - 151. 10.4274/imj.galenos.2020.99907
IEEE Alizade E,ilhan M,Mollavelioğlu B,Sormaz İ,Eröz E,SÖNMEZ R "A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer." , ss.148 - 151, 2020. 10.4274/imj.galenos.2020.99907
ISNAD Alizade, Elchin vd. "A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer". (2020), 148-151. https://doi.org/10.4274/imj.galenos.2020.99907
APA Alizade E, ilhan M, Mollavelioğlu B, Sormaz İ, Eröz E, SÖNMEZ R (2020). A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. İstanbul Medical Journal, 21(2), 148 - 151. 10.4274/imj.galenos.2020.99907
Chicago Alizade Elchin,ilhan Mehmet,Mollavelioğlu Baran,Sormaz İsmail Cem,Eröz Erhan,SÖNMEZ RECEP ERÇİN A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. İstanbul Medical Journal 21, no.2 (2020): 148 - 151. 10.4274/imj.galenos.2020.99907
MLA Alizade Elchin,ilhan Mehmet,Mollavelioğlu Baran,Sormaz İsmail Cem,Eröz Erhan,SÖNMEZ RECEP ERÇİN A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. İstanbul Medical Journal, vol.21, no.2, 2020, ss.148 - 151. 10.4274/imj.galenos.2020.99907
AMA Alizade E,ilhan M,Mollavelioğlu B,Sormaz İ,Eröz E,SÖNMEZ R A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. İstanbul Medical Journal. 2020; 21(2): 148 - 151. 10.4274/imj.galenos.2020.99907
Vancouver Alizade E,ilhan M,Mollavelioğlu B,Sormaz İ,Eröz E,SÖNMEZ R A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer. İstanbul Medical Journal. 2020; 21(2): 148 - 151. 10.4274/imj.galenos.2020.99907
IEEE Alizade E,ilhan M,Mollavelioğlu B,Sormaz İ,Eröz E,SÖNMEZ R "A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer." İstanbul Medical Journal, 21, ss.148 - 151, 2020. 10.4274/imj.galenos.2020.99907
ISNAD Alizade, Elchin vd. "A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer". İstanbul Medical Journal 21/2 (2020), 148-151. https://doi.org/10.4274/imj.galenos.2020.99907