Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats

Abdulahad Doğan, (Van Yüzüncü Yıl Üniversitesi, Eczacılık Fakültesi, Biyokimya Anabilim Dalı, Van, Türkiye)
Fatih Dönmez, (Van Yüzüncü Yıl Üniversitesi, Eczacılık Fakültesi, Biyokimya Anabilim Dalı, Van, Türkiye)
Özgür Ozan Anuk (Van Yüzüncü Yıl Üniversitesi, Sağlık Bilimleri Enstitüsü, Biyokimya Anabilim Dalı, Van, Türkiye)
Alınteri Zirai Bilimler Dergisi
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Yıl: 2020 Cilt: 35 Sayı: 1 Sayfa Aralığı: 22 - 28 Metin Dili: İngilizce DOI: 10.28955/alinterizbd.740369 İndeks Tarihi: 19-10-2020

Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats

Öz:
The aim of this study was to evaluate the protective effects of the leaf infusion of chinar (Platanusorientalis L.) on erythrocyte fragility, haematological parameters and antioxidant status againstethanol-induced oxidative stress in rats. Thirty male rats were divided into five groups: Control,Ethanol, Ethanol+Silymarin (10 mg kg-1), Ethanol+PO-20 mg mL-1infusion, and Ethanol+PO-60 mg mL1infusion. According to the results, in the Ethanol group, erythrocyte counts, red cells distribution,plateletcrit, platelet and lymphocyte levels significantly decreased compared to the Control group,while PO-60 dose-fed group showed a significant increase in haematocrit and haemoglobin valuescompared to the Ethanol group. There were significant changes in erythrocyte fragility of Ethanoland Ethanol-treatment groups at different NaCl concentrations of 0.3 and 0.6 according to Controlgroup. It was observed that PO Leaf infusion reduced the hemolysis caused by ethanol at aconcentration of 0.3% NaCl, thus reducing the values to the control values. In addition, PO leafinfusion caused a significant increase in total antioxidant status against ethanol toxicity and asignificant decrease in total oxidative status and oxidative stress index. It was concluded that POleaf infusion may have antihematotoxic effect, reducing erythrocyte fragility and increaseantioxidant capacity against ethanol toxicity.
Anahtar Kelime:

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APA dogan a, Donmez F, ANUK Ö (2020). Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. , 22 - 28. 10.28955/alinterizbd.740369
Chicago dogan abdulahad,Donmez Fatih,ANUK ÖZGÜR OZAN Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. (2020): 22 - 28. 10.28955/alinterizbd.740369
MLA dogan abdulahad,Donmez Fatih,ANUK ÖZGÜR OZAN Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. , 2020, ss.22 - 28. 10.28955/alinterizbd.740369
AMA dogan a,Donmez F,ANUK Ö Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. . 2020; 22 - 28. 10.28955/alinterizbd.740369
Vancouver dogan a,Donmez F,ANUK Ö Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. . 2020; 22 - 28. 10.28955/alinterizbd.740369
IEEE dogan a,Donmez F,ANUK Ö "Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats." , ss.22 - 28, 2020. 10.28955/alinterizbd.740369
ISNAD dogan, abdulahad vd. "Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats". (2020), 22-28. https://doi.org/10.28955/alinterizbd.740369
APA dogan a, Donmez F, ANUK Ö (2020). Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. Alınteri Zirai Bilimler Dergisi, 35(1), 22 - 28. 10.28955/alinterizbd.740369
Chicago dogan abdulahad,Donmez Fatih,ANUK ÖZGÜR OZAN Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. Alınteri Zirai Bilimler Dergisi 35, no.1 (2020): 22 - 28. 10.28955/alinterizbd.740369
MLA dogan abdulahad,Donmez Fatih,ANUK ÖZGÜR OZAN Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. Alınteri Zirai Bilimler Dergisi, vol.35, no.1, 2020, ss.22 - 28. 10.28955/alinterizbd.740369
AMA dogan a,Donmez F,ANUK Ö Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. Alınteri Zirai Bilimler Dergisi. 2020; 35(1): 22 - 28. 10.28955/alinterizbd.740369
Vancouver dogan a,Donmez F,ANUK Ö Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats. Alınteri Zirai Bilimler Dergisi. 2020; 35(1): 22 - 28. 10.28955/alinterizbd.740369
IEEE dogan a,Donmez F,ANUK Ö "Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats." Alınteri Zirai Bilimler Dergisi, 35, ss.22 - 28, 2020. 10.28955/alinterizbd.740369
ISNAD dogan, abdulahad vd. "Evaluation of the Erythrocyte Fragility, Haematological Parameters and Antioxidant Properties of Platanus orientalis Leaf Infusion Against Ethanol Toxicity in Rats". Alınteri Zirai Bilimler Dergisi 35/1 (2020), 22-28. https://doi.org/10.28955/alinterizbd.740369
Sayfa Oluşturulma Tarihi
04-04-2024 7:10

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