The Diagnostic Value of Complete Blood Test Parameters in Acute Appendicitis: We Should not Only Take into Account WBC

OCAK ,Sönmez; BÜK ,Ömer Faruk; ÇİFTCİ ,Ahmet Burak

doi:10.31067/0.2020.283

Sönmez OCAK

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Ömer Faruk BÜK

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Ahmet Burak ÇİFTCİ

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Acıbadem Üniversitesi Sağlık Bilimleri Dergisi

Yıl: 2020Cilt: 11Sayı: 4ISSN: 1309-470X / 1309-5994Sayfa Aralığı: 696 - 700Metin Dili: İngilizce

DOI: https://doi.org/10.31067/0.2020.283

8 0

İngilizce
Türkçe

The Diagnostic Value of Complete Blood Test Parameters in Acute Appendicitis: We Should not Only Take into Account WBC

Abstract: Objective: Appendectomy is the most common urgent surgical procedure but a diagnosis of acute appendicitis still remains challenging. In this retrospective study, we aimed to evaluate the value of the complete blood count (CBC) test parameters in acute appendicitis. Materials and methods: Data of 131 patients who underwent appendectomy between January 2016 – December 2016 were collected retrospectively. Demographic features, CBC parameters and final histopathological results of the patients were recorded. The patients were divided into two groups according to the final pathological results (Group 1: Acute appendicitis group, Group 2: Normal appendices group) and were compared in terms of WBC (white blood cell), platelet count, hemoglobin level, RDW (red cell distribution width), MPV (mean platelet volume) and NLR (neutrophil to lymphocyte ratio) values. Results: 13 of 131 patients had normal appendices. WBC, platelet and NLR values were signifcantly higher in Group 1 compared to the Group 2 (p<0.001, p<0.017, p<0.001 respectively). MPV value was significantly lower in Group 1 compared to the Group 2 (p<0.041). The cut-off levels for WBC, platelet, MPV and NLR were ≥9200 µL (sensitivity: 84.7%, specificity: 69.2%), ≥244500 µL (sensitivity: 57.6% specificity: 84.6%), ≤8.15 fl (sensitivity: 69.2%, specificity: 64.4%) and ≥2.795 (sensitivity: 81.4% specificity: 76.9%) respectively. Conclusion: In addition to WBC, NLR, platelet and MPV levels can be helpful for acute appendicitis diagnosis with no extra costs.

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AKUT APANDISIT TANISINDA TAM KAN SAYIMI PARAMETRELERININ TANISAL DEĞERI: SADECE BEYAZ KÜRE DEĞERINI DIKKATE ALMAMALIYIZ

Öz:Amaç: Appendektomi en sık yapılan acil cerrahi girişim olmasına rağmen akut apandisit tanısını koymakta zorluklar görülebilmektedir. Bu retrospektif çalışmada tam kan sayımı (TKS) parametrelerinin akut apandisit tanısındaki öneminin araştırması hedeflenmiştir. Gereç ve Yöntem: Ocak 2016-Aralık 2016 yılları arasında appendektomi uygulanan 131 hastanın verileri retrospektif olarak incelenmiştir. Hastaların demografik özellikleri, TKS parametreleri ve histopatolojik inceleme sonuçları kaydedilmiştir. Hastalar patoloji sonuçlarına göre iki gruba ayrılmıştır (Grup 1: akut apandisit grubu, Grup 2: normal appendiks grubu). İki grubun beyaz küre, trombosit, hemoglobulin seviyeleri ile RDW (red cell distribution width), MPV (mean platelet volume) ve NLR (nötrofil/ lenfosit oranı) değerleri karşılaştırılmıştır. Sonuçlar: Yüz otuz bir hastanın 13’ü normal appendikse sahipti. Beyaz küre, platelet ve NLR değerleri Grup 1’de anlamlı olarak daha yüksek bulundu (p<0,001, p<0,017, p<0,001). MPV değeri Grup 1’de anlamlı olarak daha düşük saptandı (p<0,041). Beyaz küre, platelet, MPV ve NLR değerleri için cutt-off değerleri sırası ile were ≥9200 µL (sensitivite: %84,7, spesifisite: 69,2%), ≥244500 µL (sensitivite: %57,6, spesifisite: %84,6), ≤8,15 fl (sensitivite: %69,2, spesifisite: %64,4) ve ≥2,795 (sensitivite: %81,4 spesifisite: %76,9) olarak bulundu. Sonuç: Beyaz küre değerine ek olarak NLR, platelet ve MPV değerleri de herhangi bir maliyete neden olmadan akut apandisit tanısında faydalı olabilir.

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Belge Türü: DergiMakale Türü: Araştırma MakalesiErişim Formatı: Erişime Açık

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