The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats

Silici, Sibel; BAYDİLLİ, NUMAN; Ekmekcioglu, Oguz; Doğanyiğit, Züleyha; Akınsal, Emre Can

doi:10.14744/etd.2020.83097

The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats

Numan BAYDİLLİ, (Erciyes Üniversitesi, Tıp Fakültesi, Üroloji Bölümü, Kayseri, Türkiye)

Emre Can AKINSAL, (Erciyes Üniversitesi, Tıp Fakültesi, Üroloji Bölümü, Kayseri, Türkiye)

Züleyha DOĞANYİĞİT, (Yozgat Bozok Üniversitesi, Tıp Fakültesi, Histoloji ve Embriyoloji Bölümü, Yozgat, Türkiye)

Oğuz EKMEKÇİOĞLU, (Erciyes Üniversitesi, Tıp Fakültesi, Üroloji Bölümü, Kayseri, Türkiye)

Sibel SİLİCİ (Erciyes Üniversitesi, Seyrani Tarım Fakültesi, Tarımsal Biyoteknoloji Bölümü, Kayseri, Türkiye)

Erciyes Medical Journal

6 0

Yıl: 2020 Cilt: 42 Sayı: 2 Sayfa Aralığı: 132 - 138 Metin Dili: İngilizce DOI: 10.14744/etd.2020.83097 İndeks Tarihi: 19-10-2020

The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats

Öz:

Objective: This study evaluated the biochemical and histopathological effects of propolis oil extract on liver and testiculartissue in rats subjected to alcohol toxicity.Materials and Methods: Sixty Wistar albino rats were randomly assigned into 6 groups: Control, Ethanol (EtOH: 20%ethanol) Propolis-1 (PR1: 100 mg/kgbw) Propolis-2 (PR2: 200 mg/kgbw) EtOH+PR1, and EtOH+PR2. Rats were administered ethanol and propolis by gastric tube for 15 days. Hematological, biochemical, and histopathological (liver and testes)parameters were examined. In addition, sperm concentration and motility were determined.Results: Increased deterioration of complete blood count parameters was statistically significant in the EtOH group whencompared to the control group. Propolis was preventative for some effects of EtOH. The most pronounced preventive effectof propolis on ethanol-induced damage was observed in nucleated red blood cells (NRBC) and mean corpuscular hemoglobinconcentration (MCHC) parameters (p<0.01). Cholesterol and triglyceride levels were found to be highest in the EtOH group,and propolis was found to reduce these effects of ethanol (p<0.01). While the highest value for the testosterone hormonewas seen in the PR2 group, propolis was found to decrease the hormone level decline caused by ethanol especially in theEtOH+PR2 group. Although it was not statistically significant, giving rats ethanol showed reduced sperm motility and epididymal sperm concentration, whereas co-administering propolis and ethanol showed an increase in these values.Conclusion: It was found that ethanol caused negative effects on the biochemical parameters studied, and histopathologicalassessments also showed negative effects on liver and testicular tissue. Propolis (200 mg/kgbw), on the other hand, wasfound to have a mitigating effect on these values.

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APA	BAYDİLLİ N, Akınsal E, Doğanyiğit Z, Ekmekcioglu O, Silici S (2020). The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. , 132 - 138. 10.14744/etd.2020.83097
Chicago	BAYDİLLİ NUMAN,Akınsal Emre Can,Doğanyiğit Züleyha,Ekmekcioglu Oguz,Silici Sibel The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. (2020): 132 - 138. 10.14744/etd.2020.83097
MLA	BAYDİLLİ NUMAN,Akınsal Emre Can,Doğanyiğit Züleyha,Ekmekcioglu Oguz,Silici Sibel The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. , 2020, ss.132 - 138. 10.14744/etd.2020.83097
AMA	BAYDİLLİ N,Akınsal E,Doğanyiğit Z,Ekmekcioglu O,Silici S The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. . 2020; 132 - 138. 10.14744/etd.2020.83097
Vancouver	BAYDİLLİ N,Akınsal E,Doğanyiğit Z,Ekmekcioglu O,Silici S The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. . 2020; 132 - 138. 10.14744/etd.2020.83097
IEEE	BAYDİLLİ N,Akınsal E,Doğanyiğit Z,Ekmekcioglu O,Silici S "The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats." , ss.132 - 138, 2020. 10.14744/etd.2020.83097
ISNAD	BAYDİLLİ, NUMAN vd. "The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats". (2020), 132-138. https://doi.org/10.14744/etd.2020.83097

APA	BAYDİLLİ N, Akınsal E, Doğanyiğit Z, Ekmekcioglu O, Silici S (2020). The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. Erciyes Medical Journal, 42(2), 132 - 138. 10.14744/etd.2020.83097
Chicago	BAYDİLLİ NUMAN,Akınsal Emre Can,Doğanyiğit Züleyha,Ekmekcioglu Oguz,Silici Sibel The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. Erciyes Medical Journal 42, no.2 (2020): 132 - 138. 10.14744/etd.2020.83097
MLA	BAYDİLLİ NUMAN,Akınsal Emre Can,Doğanyiğit Züleyha,Ekmekcioglu Oguz,Silici Sibel The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. Erciyes Medical Journal, vol.42, no.2, 2020, ss.132 - 138. 10.14744/etd.2020.83097
AMA	BAYDİLLİ N,Akınsal E,Doğanyiğit Z,Ekmekcioglu O,Silici S The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. Erciyes Medical Journal. 2020; 42(2): 132 - 138. 10.14744/etd.2020.83097
Vancouver	BAYDİLLİ N,Akınsal E,Doğanyiğit Z,Ekmekcioglu O,Silici S The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats. Erciyes Medical Journal. 2020; 42(2): 132 - 138. 10.14744/etd.2020.83097
IEEE	BAYDİLLİ N,Akınsal E,Doğanyiğit Z,Ekmekcioglu O,Silici S "The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats." Erciyes Medical Journal, 42, ss.132 - 138, 2020. 10.14744/etd.2020.83097
ISNAD	BAYDİLLİ, NUMAN vd. "The Protective Role of Poplar Propolis Against Alcohol-Induced Biochemical and Histological Changes in Liver and Testes Tissues of Rats". Erciyes Medical Journal 42/2 (2020), 132-138. https://doi.org/10.14744/etd.2020.83097