Yıl: 2020 Cilt: 42 Sayı: 2 Sayfa Aralığı: 157 - 162 Metin Dili: İngilizce DOI: 10.14744/etd.2019.57355 İndeks Tarihi: 19-10-2020

Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?

Öz:
Objective: To investigate the relationship between subjective tinnitus and red cell distribution width (RDW), platelet distribution width (PDW), mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio(PLR) levels.Materials and Methods: This retrospective research included a total of 91 patients with subjective tinnitus and a controlgroup of gender- and age-matched 65 healthy volunteers. Ear, nose, throat examination followed by pure tone audiometry,tympanometry, complete blood count, and magnetic resonance imaging of the temporal bone was performed. The clinicalfeatures and duration of tinnitus were recorded for each patient. The MPV, NLR, PDW, PLR and RDW levels were comparedbetween tinnitus and control groups.Results: Mean RDW was 15.49±2.43% in the patient group and 15.42±2.04% in the control group (p=0.831). Mean PDWwas 16.13±2.51% in the patient group and 15.99±9.94% in the control group (p=0.901). Mean MPV was 8.95±0.77 fLin the patient group and 8.55±0.75 fL in the control group (p=0.002). Mean NLR was 1.89±0.63 in the patient group and1.88±0.75 in the control group (p=0.916). Mean PLR was 113.93±33.91 in the patient group and 120.90±33.23 in thecontrol group (p=0.204). Only MPV established a significant difference between tinnitus and control groups.Conclusion: Only MPV was found to have an important role in the clinical prognosis and diagnosis of tinnitus. ElevatedMPV indicates a possible role of thrombosis and vascular diseases in the etiology of subjective tinnitus, so increased MPV canbe used as a thrombosis marker in subjective tinnitus.
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  • 1. Nondahl DM, Cruickshanks KJ, Huang GH, Klein BE, Klein R, Nieto FJ, et al. Tinnitus and its risk factors in the Beaver Dam offspring study. Int J Audiol 2011; 50(5): 313–20.
  • 2. Bauer CA. Tinnitus and Hyperacusis. In: Richardson M, Flint P, Haughey B, Lund V, Niparko J, Robbins K, et al. editors. Cummings otolaryngology: head & neck surgery. 5th ed. St Louis (MO): ElsevierMosby; 2010.p.2131–9.
  • 3. Şahin Mİ, Kökoğlu K, Gülmez E. Mean platelet volume, neutrophil- and platelet to lymphocyte ratios are elevated in vestibular neuritis. J Clin Neurosci 2019; 67: 134–8.
  • 4. Bucak A, Ulu S, Oruc S, Yucedag F, Tekin MS, Karakaya F, et al. Neutrophil-to-lymphocyte ratio as a novel-potential marker for predicting prognosis of Bell palsy. Laryngoscope 2014; 124(7): 1678–81.
  • 5. Seo YJ, Jeong JH, Choi JY, Moon IS. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss. Dis Markers 2014; 2014: 702807.
  • 6. Ulusoy B, Bozdemir K, Mişe Hİ, Kutluhan A, Korkmaz MH. Effect of septoplasty on the mean platelet volume and inflammation markers. KBB-Forum 2018; 17(2): 40–8.
  • 7. Lippi G, Targher G, Salvagno GL, Guidi GC. Increased red blood cell distribution width (RDW) is associated with higher glycosylated hemoglobin (HbA1c) in the elderly. Clin Lab 2014; 60(12): 2095–8.
  • 8. Aksoy S, Firat Y, Alpar R. The Tinnitus Handicap Inventory: a study of validity and reliability. Int Tinnitus J 2007; 13(2): 94–8.
  • 9. Kim DK, Chung DY, Bae SC, Park KH, Yeo SW, Park SN. Diagnostic value and clinical significance of stress hormones in patients with tinnitus. Eur Arch Otorhinolaryngol 2014; 271(11): 2915–21.
  • 10. Yilmaz M, Tarakcioglu M, Bayazit N, Bayazit YA, Namiduru M, Kanlikama M. Serum cytokine levels in Bell’s palsy. J Neurol Sci 2002; 197(1-2): 69–72.
  • 11. Tefferi A, Hanson CA, Inwards DJ. How to interpret and pursue an abnormal complete blood cell count in adults. Mayo Clin Proc 2005; 80(7): 923–36.
  • 12. Azab B, Bhatt VR, Phookan J, Murukutla S, Kohn N, Terjanian T, et al. Usefulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients. Ann Surg Oncol 2012; 19(1): 217–24.
  • 13. Torun S, Tunc BD, Suvak B, Yildiz H, Tas A, Sayilir A, et al. Assessment of neutrophil-lymphocyte ratio in ulcerative colitis: a promising marker in predicting disease severity. Clin Res Hepatol Gastroenterol 2012; 36(5): 491–7.
  • 14. Rachidi S, Wallace K, Wrangle JM, Day TA, Alberg AJ, Li Z. Neutrophil-to-lymphocyte ratio and overall survival in all sites of head and neck squamous cell carcinoma. Head Neck 2016; 38 Suppl 1(Suppl 1): E1068–74.
  • 15. Ozbay I, Kahraman C, Balikci HH, Kucur C, Kahraman NK, Ozkaya DP, et al. Neutrophil-to-lymphocyte ratio in patients with severe tinnitus: prospective, controlled clinical study. J Laryngol Otol 2015; 129(6): 544–7.
  • 16. Chung JH, Lim J, Jeong JH, Kim KR, Park CW, Lee SH. The significance of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in vestibular neuritis. Laryngoscope 2015; 125(7): E257–61.
  • 17. Bayram A, Yaşar M, Doğan M, Güneri E, Özcan İ. Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus. ENT Updates 2015; 5(3): 103–6.
  • 18. Atan D, Apaydın E, Özcan KM, Dere H. New diagnostic indicators in chronic otitis media with effusion: neutrophil to lymphocyte ratio and thrombocyte lymphocyte ratio. ENT Updates 2016; 6(1): 12–5.
  • 19. Turkmen K, Erdur FM, Ozcicek F, Ozcicek A, Akbas EM, Ozbicer A, et al. Platelet-to-lymphocyte ratio better predicts inflammation than neutrophil-to-lymphocyte ratio in end-stage renal disease patients. Hemodial Int 2013; 17(3): 391–6.
  • 20. Que Y, Qiu H, Li Y, Chen Y, Xiao W, Zhou Z, et al. Preoperative platelet-lymphocyte ratio is superior to neutrophil-lymphocyte ratio as a prognostic factor for soft-tissue sarcoma. BMC Cancer 2015; 15: 648.
  • 21. Verdoia M, Camaro C, Barbieri L, Schaffer A, Marino P, Bellomo G, et al. Mean platelet volume and the risk of periprocedural myocardial infarction in patients undergoing coronary angioplasty. Atherosclerosis 2013; 228(1): 136–41.
  • 22. Han JS, Park TS, Cho SY, Joh JH, Ahn HJ. Increased mean platelet volume and mean platelet volume/platelet count ratio in Korean patients with deep vein thrombosis. Platelets 2013; 24(8): 590–93.
  • 23. Sarıkaya Y, Bayraktar C, Karataş M, Doğan S, Olt S, Kaskalan E, et al. Increased mean platelet volume in patients with idiopathic subjective tinnitus. Eur Arch Otorhinolaryngol 2016; 273(11): 3533–6.
  • 24. Akil F, Yollu U, Turgut F, Ayral M, Akil E. The Relationship between Tinnitus, Mean Platelet Volume and Neutrophile/Lymphocyte RatioInvestigation on the New Focus of the literature. Otlonline 2017; 7(1): 148.
  • 25. Salvagno GL, Sanchis-Gomar F, Picanza A, Lippi G. Red blood cell distribution width: A simple parameter with multiple clinical applications. Crit Rev Clin Lab Sci 2015; 52(2): 86–105.
  • 26. Nakashima K, Ohgami E, Kato K, Yoshitomi S, Maruyama T, Harada M. Prognostic significance of red cell distribution width in hospitalized older patients with heart failure or infection. Geriatr Gerontol Int 2019; 19(10): 988–92.
  • 27. Sahin C, Varim C, Karacaer C. Investigation of neutrophil-to-lymphocyte ratio and red cell distribution width in sudden senseurineural hearing loss. Int J Adv Med 2019; 6(2): 424–8.
  • 28. Yu J, Wang L, Peng Y, Xiong M, Cai X, Luo J, et al. Dynamic Monitoring of Erythrocyte Distribution Width (RDW) and Platelet Distribution Width (PDW) in Treatment of Acute Myocardial Infarction. Med Sci Monit 2017; 23: 5899–906.
  • 29. Düzenli U, Bozan N, Aslan M, Özkan H, Turan M, Kıroğlu AF. A retrospective analysis of haemotologic parameters in patients with bilateral tinnitus. East J Med 2018; 23(4): 264–8.
  • 30. Kemal O, Müderris T, Başar F, Kutlar G, Gül F. Prognostic value of mean platelet volume on tinnitus. J Laryngol Otol 2016; 130(2): 162–5.
APA AVCI D (2020). Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. , 157 - 162. 10.14744/etd.2019.57355
Chicago AVCI DENİZ Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. (2020): 157 - 162. 10.14744/etd.2019.57355
MLA AVCI DENİZ Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. , 2020, ss.157 - 162. 10.14744/etd.2019.57355
AMA AVCI D Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. . 2020; 157 - 162. 10.14744/etd.2019.57355
Vancouver AVCI D Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. . 2020; 157 - 162. 10.14744/etd.2019.57355
IEEE AVCI D "Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?." , ss.157 - 162, 2020. 10.14744/etd.2019.57355
ISNAD AVCI, DENİZ. "Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?". (2020), 157-162. https://doi.org/10.14744/etd.2019.57355
APA AVCI D (2020). Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. Erciyes Medical Journal, 42(2), 157 - 162. 10.14744/etd.2019.57355
Chicago AVCI DENİZ Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. Erciyes Medical Journal 42, no.2 (2020): 157 - 162. 10.14744/etd.2019.57355
MLA AVCI DENİZ Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. Erciyes Medical Journal, vol.42, no.2, 2020, ss.157 - 162. 10.14744/etd.2019.57355
AMA AVCI D Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. Erciyes Medical Journal. 2020; 42(2): 157 - 162. 10.14744/etd.2019.57355
Vancouver AVCI D Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?. Erciyes Medical Journal. 2020; 42(2): 157 - 162. 10.14744/etd.2019.57355
IEEE AVCI D "Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?." Erciyes Medical Journal, 42, ss.157 - 162, 2020. 10.14744/etd.2019.57355
ISNAD AVCI, DENİZ. "Can Mean Platelet Volume be Used as a Thrombosis Marker in Subjective Tinnitus?". Erciyes Medical Journal 42/2 (2020), 157-162. https://doi.org/10.14744/etd.2019.57355