New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio

DERE, YELDA; Bozkurt Koseoglu, Sezen

New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio

Sezen BOZKURT KÖSEOĞLU, (Muğla Sıtkı Koçman Üniversitesi, Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Bölümü ve Jinekoloji, Muğla, Türkiye)

Yelda DERE (Muğla Sıtkı Koçman Üniversitesi, Eğitim ve Araştırma Hastanesi, Patoloji Bölümü, Muğla, Türkiye)

Ege Klinikleri Tıp Dergisi

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Yıl: 2019 Cilt: 57 Sayı: 2 Sayfa Aralığı: 143 - 147 Metin Dili: İngilizce İndeks Tarihi: 24-10-2020

New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio

Öz:

Aim: Endometrial polyps (EP) and endometrial hyperplasia (EH) are the two ofthe most common causes of abnormal uterine bleeding. The aim of this study toevaluate the differentiation of EP and EH in patients by using neutrophil-tolymphocyte raito (NLR) and platelet-to-lymphocyte ratio (PLR) which areinflammatory markers.Methods: This retrospective study consists of 108 patients diagnosed with EPand 80 patients diagnosed with EH without atypia. Ten cc of venous bloodsample from every patient. Hemoglobin, MCV (mean corpuscular volume), RDW(red cell distrubution width), MPV (mean platelet volume), numbers oflymphocytes, neutrophils, platelets, plateletcrit. NLR end PLR values wererecorded.Results: NLR values were found as 2.82.79 in EP group and 2.21.30 in EHgroup. (P=0.022). PLR values were 157.7483.14 in EP group and 139.8759.20 inEH group (P=0.024). There were significcant differecnces in terms of PLR and NLRvalues.Conclucion: EH and EPs can be differentiated before the intervention with NLRand PLR which are simple, easily accessible, repeatable and inexpensivemethods.

Anahtar Kelime:

Bening Endometrial Lezyonlar İçin Yeni Öngörücü Parametreler: Platelet Lenfosit Oranı ve Nötrofil Lenfosit Oranı'

Öz:

Amaç: Endometrial polip (EP) ve endometrial hiperplazi (EH) anormal uterin kanamaların en sık sebeplerindendir. Bu çalışmanın amacı EP ve EH ayrımında inflamatuar belirteçler olan nötrofil-lenfosit oranı (NLO) ve platelet-lenfosit oranı (PLO) kullanımını değerlendirmektir. Yöntem: Bu çalışmaya 108 EP’li ve 80 atipisi olmayan EH’li hasta retrospektif olarak dahil edildi. Her hastadan 10 cc venöz kan örneği alındı. Hemoglobin, MCV (mean corpuscular volume), RDW (red cell distrubution width), MPV (mean platelet volume), lenfosit, platelet, nötrofil, plateletcrit NLO ve PLO değerleri kaydedildi. Sonuçlar: NLO, EP grubunda 2.82.79 bulunurken, EH grubunda 2.21.30 idi. (P=0.022). PLO değeri ise EP grubunda 157.7483.14 ve EH grubunda 139.8759.20 bulundu (P=0.024). PLO ve NLO oranı için gruplar arasında istatistiksel olarak anlamlı düzeyde farklılık saptandı. Sonuç: EH ve EP’yi patolojik tanı öncesi, kolay ulaşılabilen, basit, tekrarlanabilir ve ucuz bir metod olan NLO ve PLO ile ayırmak mümkündür.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Bozkurt Koseoglu S, DERE Y (2019). New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. , 143 - 147.
Chicago	Bozkurt Koseoglu Sezen,DERE YELDA New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. (2019): 143 - 147.
MLA	Bozkurt Koseoglu Sezen,DERE YELDA New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. , 2019, ss.143 - 147.
AMA	Bozkurt Koseoglu S,DERE Y New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. . 2019; 143 - 147.
Vancouver	Bozkurt Koseoglu S,DERE Y New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. . 2019; 143 - 147.
IEEE	Bozkurt Koseoglu S,DERE Y "New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio." , ss.143 - 147, 2019.
ISNAD	Bozkurt Koseoglu, Sezen - DERE, YELDA. "New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio". (2019), 143-147.

APA	Bozkurt Koseoglu S, DERE Y (2019). New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. Ege Klinikleri Tıp Dergisi, 57(2), 143 - 147.
Chicago	Bozkurt Koseoglu Sezen,DERE YELDA New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. Ege Klinikleri Tıp Dergisi 57, no.2 (2019): 143 - 147.
MLA	Bozkurt Koseoglu Sezen,DERE YELDA New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. Ege Klinikleri Tıp Dergisi, vol.57, no.2, 2019, ss.143 - 147.
AMA	Bozkurt Koseoglu S,DERE Y New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. Ege Klinikleri Tıp Dergisi. 2019; 57(2): 143 - 147.
Vancouver	Bozkurt Koseoglu S,DERE Y New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio. Ege Klinikleri Tıp Dergisi. 2019; 57(2): 143 - 147.
IEEE	Bozkurt Koseoglu S,DERE Y "New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio." Ege Klinikleri Tıp Dergisi, 57, ss.143 - 147, 2019.
ISNAD	Bozkurt Koseoglu, Sezen - DERE, YELDA. "New Predictive Markers For Benign Endometrial Lesions: Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratio". Ege Klinikleri Tıp Dergisi 57/2 (2019), 143-147.