Yıl: 2020 Cilt: 29 Sayı: 2 Sayfa Aralığı: 129 - 135 Metin Dili: İngilizce DOI: 10.5336/ophthal.2019-70114 İndeks Tarihi: 24-10-2020

The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking

Öz:
Objective: To assess the effectiveness of accelerated cross-linking (CXL) on cornea periphery by comparing stromal de- marcation line (SDL) depths in accelerated CXL with conventional CXL. Material and Methods: Patients with progressive keratoconus who were applied conventional 30 minutes CXL with 3 mW/cm2 (conventional group) or accelerated 10 minutes CXL with 9 mW/cm2 (accelerated group) were involved in the study. The SDL was mea- sured in central and 3 mm periphery at the postoperative first month by using anterior segment optical coherence tomography. The SDL in the periphery was calculated as the proportion of central for each group seperately (SDL in the periphery/SDL in the central*100). The proportions were compared between two groups. Results: The mean central SDL depths in conventional and standard group were 302±49 μm and 251±42 μm, respectively (p: 0.004). The mean SDL per- centages at 3-mm periphery ( superior, inferior, temporal, nazal) in conventional group were 84±14, 76±18, 77±12 ve 71±12, respec- tively. The same measurements in accelerated group were 74±12, 76±08, 70±12 and 70±12, respectively. Apart from the superior pe- ripheral cornea there was no difference between two groups (p: 0.079). The SDL percentage at superior cornea was lower in accel- erated group compared to conventional group (p: 0.044). Conclu- sion: The SDL percentage at superior cornea is lower in accelerated group compared to conventional group. It is a convenient advice to think again while deciding application of accelerated CXL in condi- tions effecting superior cornea.
Anahtar Kelime:

Periferal Korneal Stromal Demarkasyon Hat Derinliği Yüzdelerinin Standard ve Hızlandırılmış Kollajen Çapraz Bağlama Sonrası Kıyaslanması

Öz:
Amaç: Standard ve hızladırılmış protokol kollajen çapraz bağ- lama (KÇB) tedavisi sonrası santral ve periferik stromal demarkas- yon hat (SDH) derinliğini kıyaslayıp hızlandırılmış protokolün kornea periferindeki etkinliğini değerlendirmek. Gereç ve Yöntemler: Otuz dakika boyunca 3 mW/cm2 dozunda standard protokol (standard grup) veya 10 dakika boyunca 9 mW/cm2 dozunda hızlandırılmış protokol (hızlandırılmış grup) KÇB uygulanmış ilerleyici keratokonus hastalığı olan kişiler çalışmaya dâhil edildi. SDH santral ve 3 mm periferden ön segment optik koherens tomografi kullanılarak postoperatif birinci ayda ölçüldü. Perifer SDH santralin yüzdesi şeklinde her grup için hesaplandı (perifer SDH/ santral SDH* 100). Yüzdeler iki grup ara- sında kıyaslandı. Bulgular: Çalışmaya 26 hastanın 42 gözü dâhil edildi, 38 gözde SDH gözlenebildi. (Bunlardan 18’i standard grup, 20’si hızlandırılmış gruptaydı). Standard ve hızlandırılmış grupta santral SDH derinliği sırasıyla 302±49 μm ve 251±42 μm idi (p=0,004). Üç mm periferden (üst, alt, temporal, nazal) ölçülen orta- lama SDH yüzdeleri standard grupta sırasıyla 84±14, 76±18, 77±12 ve 71±12 idi. Aynı ölçümler hızlandırılmış grupta sırasıyla 74±12, 76±08, 70±12 ve 70±12 idi. Üst bölge hariç iki grup arasında fark yoktu (p>0,05). Üst korneada SDH yüzdesi hızlandırılmış grupta stan- dard gruba kıyasla daha düşük bulundu (p= 0,044). Sonuç: Üst ko- rneada SDH yüzdesel olarak hızlandırılmış grupta standard gruba kıyasla daha düşüktür. Klinik uygulamalarda korneanın üst bölgesini etkileyen durumlar için KÇB tedavisi yapılacak hastalarda hızlandırılmış protokol uygulama kararı alırken tekrar düşünülmesi yerinde olacaktır
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Çiçek A, ataş m, Ulusoy D, Duru N, Demircan S (2020). The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. , 129 - 135. 10.5336/ophthal.2019-70114
Chicago Çiçek Ayşe,ataş mustafa,Ulusoy Döndü Melek,Duru Necati,Demircan Suleyman The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. (2020): 129 - 135. 10.5336/ophthal.2019-70114
MLA Çiçek Ayşe,ataş mustafa,Ulusoy Döndü Melek,Duru Necati,Demircan Suleyman The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. , 2020, ss.129 - 135. 10.5336/ophthal.2019-70114
AMA Çiçek A,ataş m,Ulusoy D,Duru N,Demircan S The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. . 2020; 129 - 135. 10.5336/ophthal.2019-70114
Vancouver Çiçek A,ataş m,Ulusoy D,Duru N,Demircan S The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. . 2020; 129 - 135. 10.5336/ophthal.2019-70114
IEEE Çiçek A,ataş m,Ulusoy D,Duru N,Demircan S "The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking." , ss.129 - 135, 2020. 10.5336/ophthal.2019-70114
ISNAD Çiçek, Ayşe vd. "The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking". (2020), 129-135. https://doi.org/10.5336/ophthal.2019-70114
APA Çiçek A, ataş m, Ulusoy D, Duru N, Demircan S (2020). The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. Türkiye Klinikleri Oftalmoloji Dergisi, 29(2), 129 - 135. 10.5336/ophthal.2019-70114
Chicago Çiçek Ayşe,ataş mustafa,Ulusoy Döndü Melek,Duru Necati,Demircan Suleyman The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. Türkiye Klinikleri Oftalmoloji Dergisi 29, no.2 (2020): 129 - 135. 10.5336/ophthal.2019-70114
MLA Çiçek Ayşe,ataş mustafa,Ulusoy Döndü Melek,Duru Necati,Demircan Suleyman The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. Türkiye Klinikleri Oftalmoloji Dergisi, vol.29, no.2, 2020, ss.129 - 135. 10.5336/ophthal.2019-70114
AMA Çiçek A,ataş m,Ulusoy D,Duru N,Demircan S The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. Türkiye Klinikleri Oftalmoloji Dergisi. 2020; 29(2): 129 - 135. 10.5336/ophthal.2019-70114
Vancouver Çiçek A,ataş m,Ulusoy D,Duru N,Demircan S The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking. Türkiye Klinikleri Oftalmoloji Dergisi. 2020; 29(2): 129 - 135. 10.5336/ophthal.2019-70114
IEEE Çiçek A,ataş m,Ulusoy D,Duru N,Demircan S "The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking." Türkiye Klinikleri Oftalmoloji Dergisi, 29, ss.129 - 135, 2020. 10.5336/ophthal.2019-70114
ISNAD Çiçek, Ayşe vd. "The Comparison of Peripheral Corneal Stromal Demarcation Line Depth Percentages After Standard and Accelerated Collagen Crosslinking". Türkiye Klinikleri Oftalmoloji Dergisi 29/2 (2020), 129-135. https://doi.org/10.5336/ophthal.2019-70114