Yıl: 2020 Cilt: 21 Sayı: 2 Sayfa Aralığı: 110 - 115 Metin Dili: İngilizce DOI: 10.5152/TurkThoracJ.2019.18202 İndeks Tarihi: 06-10-2020

Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation

Öz:
OBJECTIVES: The aim of this study was to evaluate the effect of comprehensive, 8-week outpatient pulmonary rehabilitation (PR) programme consisting of 60-min sessions twice a week under supervision on dyspnea and exercise capacity of patients who were lungtransplantation (LTx) candidates.MATERIALS AND METHODS: Between March 2012 and December 2014, medical data of 23 patients on the waiting list for LTx whowere referred to our PR unit and completed 16-session outpatient under direct supervision were retrospectively analyzed. Data on exercise capacity as assessed by 6-minute walking test (6MWT) and the rate of perceived dyspnea as assessed by the Borg scale and MedicalResearch Council (MRC) dyspnea scale were recorded.RESULTS: Of 23 patients 57% were males; the mean age was 35±10 (range: 16–48) years. Four patients were operated early, as an appropriate donor was available. Diagnosis was as follows: bronchiectasis (n=10, 44%), silicosis (n=7, 30%), sarcoidosis (n=2, 9%), idiopathicpulmonary firosis (n=1, 4%), chronic obstructive pulmonary disease (n=1, 4%), and others (n=2, 9%). At the end of the program, therewas a signifiant improvement (median: 60 m) in 6MWT scores (360 [70–254] m vs. 300 [139–489] m; p=0.018). In addition, a clinicalimprovement was observed in Borg (p=0.000) and MRC scores (p=0.008).CONCLUSION: Our study results suggest that 8-week outpatient PR programme consisting of training twice a week is effective to decrease perceived dyspnea and to improve exercise capacity in patients who are on the waiting list for LTx.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Florian, J, Rubin A, Mattiello R, et al. Impact of pulmonary rehabilitation on quality of life and functional capacity in patients on waiting lists for lung transplantation. J Bras Pneumol 2013;39:349-56. [CrossRef]
  • 2. Hook JL, Lederer DJ. Selecting lung transplant candidates: where do current guidelines fall short? Expert Rev Respir Med 2012;6:51-61. [CrossRef]
  • 3. Rochester CL. Pulmonary rehabilitation for patients who undergo lung-volume-reduction surgery or lung transplantation. Respir Care 2008;53:1196-202.
  • 4. Foster S, Thomas HM 3rd. Pulmonary rehabilitation in lung disease other than chronic obstructive pulmonary disease. Am Rev Respir Dis 1990;141:601-4. [CrossRef]
  • 5. Pehlivan E, Balcı A, Kılıç L, et al. Preoperative Pulmonary Rehabilitation for Lung Transplant: Effects on Pulmonary Function, Exercise Capacity, and Quality of Life; First Results in Turkey. Exp Clin Transplant 2018;16:455-60.
  • 6. Ries AL, Bauldoff GS, Carlin BW, et al. Pulmonary Rehabilitation: Joint ACCP/AACVPR Evidence-Based Clinical Practice Guidelines. Chest 2007;131:4-42. [CrossRef]
  • 7. Nici L, Donner C, Wouters E, et al. American Thoracic Society/ European Respiratory Society statement on pulmonary rehabilitation. Am J Respir Crit Care Med 2006;173:1390-413. [CrossRef]
  • 8. Wijkstra PJ, Wempe JB. New tools in pulmonary rehabilitation. Eur Respir J 2011;38:1468-74. [CrossRef]
  • 9. Mathur S, Hornblower E, Levy RD. Exercise training before and after lung transplantation. Phys Sportsmed 2009;37:78-87. [CrossRef]
  • 10. Langer D. Rehabilitation in patients before and after lung transplantation. Respiration 2015;89:353-62. [CrossRef]
  • 11. Gloeckl R, Halle M, Kenn K. Interval versus continuous training in lung transplant candidates: a randomized trial. J Heart Lung Transplant 2012;31:934-41. [CrossRef]
  • 12. Li M, Mathur S, Chowdhury NA, et al. Pulmonary rehabilitation in lung transplant candidates. J Heart Lung Transplant 2013;32:626-32. [CrossRef]
  • 13. Rochester CL, Fairburn C, Crouch RH. Pulmonary rehabilitation for respiratory disorders other than chronic obstructive pulmonary disease. Clin Chest Med 2014;35:369-89. [CrossRef]
  • 14. Trojetto T, Elliott RJ, Rashid S, et al. Availability, characteristics, and barriers of rehabilitation programs in organ transplant populations across Canada. Clin Transplant 2011;25:E571-8. [CrossRef]
  • 15. Wickerson L, Rozenberg D, Janaudis-Ferreira T, et al. Physical rehabilitation for lung transplant candidates and recipients: An evidence-informed clinical approach. World J Transplant 2016;6:517-31. [CrossRef]
  • 16. Puente-Maestu L, Sánz ML, Sánz P, et al. Comparison of effects of supervised versus self-monitored training programmes in patients with chronic obstructive pulmonary disease. Eur Respir J 2000;15:517-25. [CrossRef]
  • 17. O'Neill B, McKevitt A, Rafferty S, et al. A comparison of twiceversus once-weekly supervision during pulmonary rehabilitation in chronic obstructive pulmonary disease. Arch Phys Med Rehabil 2007;88:167-72. [CrossRef]
  • 18. Spruit MA, Pitta F, Garvey C, et al. Differences in content and organisational aspects of pulmonary rehabilitation programmes. Eur Respir J 2014;43:1326-37. [CrossRef]
  • 19. Kenn K, Gloeckl R, Soennichsen A, et al. Predictors of success for pulmonary rehabilitation in patients awaiting lung transplantation. Transplantation 2015;99:1072-7. [CrossRef]
  • 20. Vivodtzev I, Pison C, Guerrero K, et al. Benefis of home-based endurance training in lung transplant recipients. Respir Physiol Neurobiol 2011;177:189-98. [CrossRef]
  • 21. Jastrzebski D, Gawlik R, Kozielski J, et al. Dyspnea and quality of life in patients with pulmonary firosis after six weeks of respiratory rehabilitation. J Physiol Pharmacol 2006;57:139- 48.
  • 22. Johnston CL, Maxwell LJ, Alison JA. Pulmonary rehabilitation in Australia: a national survey. Physiotherapy 2011;97:284-90. [CrossRef]
  • 23. International guidelines for the selection of lung transplant candidates. The American Society for Transplant Physicians (ASTP)/American Thoracic Society(ATS)/European Respiratory Society(ERS)/International Society for Heart and Lung Transplantation(ISHLT). Am J Respir Crit Care Med 1998;158:335-9. [CrossRef]
  • 24. Orens JB, Estenne M, Arcasoy S, et al. International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientifi Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant 2006;25:745-55. [CrossRef]
  • 25. Brooks D, Solway S, Gibbons WJ. ATS statement on six-minute walk test. Am J Respir Crit Care Med 2003;167:1287. [CrossRef]
  • 26. Holland AE, Spruit MA, Troosters T, et al. An offiial European Respiratory Society/American Thoracic Society technical standard: fild walking tests in chronic respiratory disease. Eur Respir J 2014;44:1428-46. [CrossRef]
  • 27. Fletcher CM, Elmes PC, Fairbairn AS, et al. The signifiance of respiratory symptoms and the diagnosis of chronic bronchitis in a working population. Br Med J 1959;2:257-66. [CrossRef]
  • 28. Antoniu SA. Descriptors of dyspnea in obstructive lung diseases. Multidiscip Respir Med 2010;5:216-9. [CrossRef]
  • 29. Pehlivan E, Mutluay F, Balcı A, et al. The effects of inspiratory muscle training on exercise capacity, dyspnea and respiratory functions in lung transplantation candidates: a randomized controlled trial. Clin Rehabil 2018;32:1328-39. [CrossRef]
  • 30. Büyükkale S, Bakan ND, Isgörücü Ö, et al. Late-breaking abstract: First 24 lung transplantations: Single center results from Turkey. Eur Respir J 2014;44:P2450.
  • 31. Dabak G, Dalar L, Taşçı E, et al. Lung transplantation in Turkey: lessons from surgeons and pulmonologists. Turk J Med Sci 2016;46:1434-42. [CrossRef]
  • 32. Beauchamp MK, Evans R, Janaudis-Ferreira T, et al. Systematic review of supervised exercise programs after pulmonary rehabilitation in individuals with COPD. Chest 2013;144:1124-33. [CrossRef]
  • 33. Ringbaek TJ, Broendum E, Hemmingsen L, et al. Rehabilitation of patients with chronic obstructive pulmonary disease. Exercise twice a week is not suffiient! Respir Med 2000;94:150-4. [CrossRef]
  • 34. British Thoracic Society Standards of Care Subcommittee on Pulmonary Rehabilitation. Pulmonary rehabilitation. Thorax 2001;56:827-34. [CrossRef]
  • 35. Holland AE, Hill CJ, Glaspole I, et al. Predictors of benefi following pulmonary rehabilitation for interstitial lung disease. Respir Med 2012;106:429-35. [CrossRef]
  • 36. Liddell F, Webber J. Pulmonary rehabilitation for chronic obstructive pulmonary disease: a pilot study evaluating a onceweekly versus twice-weekly supervised programme. Physiotherapy 2010;96:68-74. [CrossRef]
  • 37. Jastrzebski D, Ochman M, Ziora D, et al. Pulmonary rehabilitation in patients referred for lung transplantation. Adv Exp Med Biol 2013;755:19-25. [CrossRef]
APA Kılıç l, PEHLİVAN E, Balcı A, Bakan N (2020). Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. , 110 - 115. 10.5152/TurkThoracJ.2019.18202
Chicago Kılıç lütfiye,PEHLİVAN ESRA,Balcı Arif,Bakan Nur Dilek Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. (2020): 110 - 115. 10.5152/TurkThoracJ.2019.18202
MLA Kılıç lütfiye,PEHLİVAN ESRA,Balcı Arif,Bakan Nur Dilek Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. , 2020, ss.110 - 115. 10.5152/TurkThoracJ.2019.18202
AMA Kılıç l,PEHLİVAN E,Balcı A,Bakan N Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. . 2020; 110 - 115. 10.5152/TurkThoracJ.2019.18202
Vancouver Kılıç l,PEHLİVAN E,Balcı A,Bakan N Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. . 2020; 110 - 115. 10.5152/TurkThoracJ.2019.18202
IEEE Kılıç l,PEHLİVAN E,Balcı A,Bakan N "Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation." , ss.110 - 115, 2020. 10.5152/TurkThoracJ.2019.18202
ISNAD Kılıç, lütfiye vd. "Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation". (2020), 110-115. https://doi.org/10.5152/TurkThoracJ.2019.18202
APA Kılıç l, PEHLİVAN E, Balcı A, Bakan N (2020). Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. Turkish Thoracic Journal, 21(2), 110 - 115. 10.5152/TurkThoracJ.2019.18202
Chicago Kılıç lütfiye,PEHLİVAN ESRA,Balcı Arif,Bakan Nur Dilek Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. Turkish Thoracic Journal 21, no.2 (2020): 110 - 115. 10.5152/TurkThoracJ.2019.18202
MLA Kılıç lütfiye,PEHLİVAN ESRA,Balcı Arif,Bakan Nur Dilek Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. Turkish Thoracic Journal, vol.21, no.2, 2020, ss.110 - 115. 10.5152/TurkThoracJ.2019.18202
AMA Kılıç l,PEHLİVAN E,Balcı A,Bakan N Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. Turkish Thoracic Journal. 2020; 21(2): 110 - 115. 10.5152/TurkThoracJ.2019.18202
Vancouver Kılıç l,PEHLİVAN E,Balcı A,Bakan N Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation. Turkish Thoracic Journal. 2020; 21(2): 110 - 115. 10.5152/TurkThoracJ.2019.18202
IEEE Kılıç l,PEHLİVAN E,Balcı A,Bakan N "Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation." Turkish Thoracic Journal, 21, ss.110 - 115, 2020. 10.5152/TurkThoracJ.2019.18202
ISNAD Kılıç, lütfiye vd. "Effect of 8-week Pulmonary Rehabilitation Program on Dyspnea and Functional Capacity of Patients on Waiting List for Lung Transplantation". Turkish Thoracic Journal 21/2 (2020), 110-115. https://doi.org/10.5152/TurkThoracJ.2019.18202